Category	Term	Count	%	Pvalue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
KEGG_PATHWAY	hsa05200:Pathways in cancer	270	14.523937600860679	1.2139499546948859E-95	ARNT, RASSF5, ADCY9, CDKN2A, ARAF, CXCR4, CDKN2B, WNT5B, ADCY1, ADCY2, FZD2, MDM2, PLCG2, RUNX1T1, FZD5, LEF1, PRKACB, PDGFB, CASP9, GNA11, BAD, ROCK1, GNA13, BCL2L1, LAMA5, BAX, RHOA, RELA, EGF, BID, BDKRB1, TGFB1, CDKN1B, E2F3, COL4A3, CBL, PLCB1, PRKCA, CREBBP, ARHGEF12, GNG12, HSP90B1, ITGAV, AKT2, FGFR2, RAC3, FZD7, MYC, PPARG, FOS, RET, WNT3A, FGF13, GLI3, GLI2, PLCG1, JUP, MAPK3, CDK2, GNG3, RAF1, GNG5, PTK2, BRCA2, KRAS, EGFR, GNGT1, STAT3, NRAS, AKT1, TGFBR1, IGF1, GNG4, GNG10, AXIN1, PDGFRA, PLCB3, CTNNA1, COL4A5, GRB2, ADCY5, GNAI1, TCF7L2, TCF7L1, GNAS, PRKCB, TRAF4, JUN, TGFBR2, PGF, PIK3R2, F2R, CCDC6, VEGFC, VEGFB, MITF, GNAI2, HDAC1, AR, HSP90AA1, RARA, PIK3CD, GNB2, HGF, STAT5B, PAX8, RBX1, GNB5, FLT3, JAK1, EP300, PIK3R5, PRKCG, GNG8, GNAQ, NFKB1, LAMA1, CXCL8, CCND1, FZD4, TCF7, EPAS1, PRKACG, MMP9, FGF10, MAPK10, SMAD3, PLCB4, ITGA3, COL4A1, FGF2, BCR, RAC2, APC, CDKN1A, CKS2, MAP2K2, FZD9, CEBPA, GNB4, BRAF, BCL2, RB1, E2F1, ADCY7, ITGB1, CASP8, COL4A2, NFKBIA, PTGS2, CCNE1, RUNX1, ADCY4, GNG13, AXIN2, SOS1, PDGFA, TFG, CXCL12, HSP90AB1, MAPK9, DVL2, DVL1, SOS2, MAPK8, ARHGEF1, CDC42, IKBKB, CKS1B, MLH1, MAP2K1, SUFU, NOS2, TGFB2, IL6, TRAF5, CTNNB1, FGF1, AKT3, ITGA2, MAPK1, MTOR, GLI1, TRAF3, GNAI3, ADCY3, FGFR3, HIF1A, TRAF2, AGTR1, GNG7, BDKRB2, DVL3, ADCY6, CYCS, SMAD2, PIK3CB, CTNNA3, MMP2, PIK3CA, CDK4, FAS, FGF12, MMP1, CTNNA2, FZD6, FGF3, STAT1, CCNE2, HDAC2, PIK3CG, WNT10A, FOXO1, STAT5A, PIK3R1, CDH1, PIK3R3, DAPK1, CDK6, CSF3R, PRKACA, PLCB2, PIAS2, GSK3B, CBLB, FGF7, SPI1, ABL1, RAC1, TP53, FASLG, FGF18, COL4A6, IGF1R, VEGFA, PTEN, KITLG, FN1, CSF1R, RXRG, MET, BIRC3, GNG2, CHUK, GNB3, CRKL, BIRC2, CTBP1, NFKB2, RXRB, ERBB2, FADD, WNT1, NTRK1, LAMC1, TRAF6, FZD8, IKBKG, CRK, PPARD, NKX3-1, FZD10, ADCY8, KIT, CBLC, SMAD4, ZBTB16, CASP3, ITGA6, PML	1481	393	6910	3.205488348598791	3.156269882206703E-93	3.156269882206703E-93	1.58676489185602E-92
KEGG_PATHWAY	hsa04151:PI3K-Akt signaling pathway	233	12.533620225927919	2.0175125136689942E-79	PPP2R2D, TLR4, RPS6, MDM2, INS, PDGFB, CASP9, BAD, MCL1, BCL2L1, LAMA5, ITGA1, YWHAE, CRTC2, PPP2CA, RELA, IL3RA, EGF, TLR2, CDKN1B, NGF, IFNA8, COL4A3, PRKCA, EFNA1, GNG12, HSP90B1, ITGAV, AKT2, SYK, FGFR2, MYC, YWHAZ, FGF13, PPP2R3A, MAPK3, CDK2, GNG3, RAF1, OSMR, GNG5, PTK2, YWHAH, MYB, KRAS, IBSP, EGFR, GNGT1, AKT1, NRAS, ITGA5, IGF1, DDIT4, GNG4, PPP2CB, GNG10, NGFR, PPP2R1B, PDGFRA, PPP2R1A, YWHAB, SPP1, COL4A5, RELN, GRB2, CREB3L3, CREB3, PPP2R3C, CREB5, IFNAR1, ITGB3, COL1A2, CREB1, VWF, PGF, PIK3R2, IFNA4, F2R, IFNA16, IFNA6, IFNA10, VEGFC, IFNA21, IFNA5, VEGFB, CCND2, IFNA1, RPS6KB1, IL7R, YWHAG, HSP90AA1, PIK3CD, HGF, GNB2, IFNA14, IFNA17, CCND3, GNB5, JAK1, ATF4, PIK3R5, IFNB1, GNG8, EIF4EBP1, ATF2, NFKB1, LAMA1, PRLR, TCL1A, VTN, EFNA4, EFNA5, CCND1, PDGFD, CREB3L4, TSC2, FGF10, ITGA3, COL4A1, PPP2R2C, ITGB8, FGF2, PDPK1, COL2A1, ITGB7, CHRM2, CDKN1A, INSR, PHLPP2, MAP2K2, GNB4, BCL2, BCL2L11, ANGPT2, IL4R, ITGB1, COL6A3, COL4A2, CCNE1, GNG13, SOS1, PDGFA, PDGFC, FOXO3, HSP90AB1, IL2RB, SOS2, IL2RA, PPP2R5E, IKBKB, MAP2K1, IL6, FGF1, TNXB, AKT3, ITGA2, JAK2, MAPK1, MTOR, CREB3L2, PRKAA1, GYS2, PPP2R5A, FGFR3, COL1A1, ANGPT4, GNG7, PPP2R5B, IL2, CSF1, PIK3CB, PIK3CA, CDK4, IFNAR2, PKN1, FGF12, IL2RG, FGF3, PPP2R2A, CCNE2, PIK3CG, IRS1, JAK3, PIK3R1, CREB3L1, PIK3R3, RHEB, PPP2R2B, CDK6, CSF3R, GYS1, CSH2, ANGPT1, GSK3B, PHLPP1, FGFR4, FGF7, FLT1, RAC1, TP53, FASLG, TSC1, FGF18, COL4A6, IGF1R, KDR, VEGFA, PTEN, PRL, THBS2, FN1, KITLG, CSF1R, GHR, MET, GNG2, CHUK, GNB3, PPP2R5C, BRCA1, NOS3, PPP2R5D, LAMC1, NR4A1, THBS1, IKBKG, PCK1, EIF4E, KIT, ATF6B, EPOR, TNR, ITGA6	1481	345	6910	3.151082797561381	5.245532535539385E-77	2.6227662677696923E-77	2.6371087318626473E-76
KEGG_PATHWAY	hsa05166:HTLV-I infection	183	9.84400215169446	7.341668455548807E-68	FZD4, CCND1, ADCY9, ANAPC1, ELK1, RRAS2, MAP3K14, CDC20, PRKACG, CDKN2A, SMAD3, WNT5B, CDKN2B, ADCY2, ADCY1, EGR1, NFATC2, FDPS, FZD2, IL1R1, XBP1, FZD5, APC, HLA-DMB, CDKN1A, FZD9, PRKACB, PDGFB, RB1, E2F1, ADCY7, TLN1, NFKBIA, ADCY4, PDGFA, HLA-DRA, BCL2L1, RELB, IL2RB, BAX, CRTC2, RELA, DVL2, MAP2K4, DVL1, IL2RA, E2F3, TGFB1, LCK, IKBKB, VDAC2, IL1R2, CREBBP, POLD2, IL6, TGFB2, CTNNB1, ATM, AKT3, NFATC1, POLD1, AKT2, ETS2, FZD7, MYC, SRF, FOS, CREM, WNT3A, ADCY3, CD40, MAP3K1, ETS1, TBP, TBPL1, KAT5, SLC25A4, DVL3, ADCY6, IL2, SMAD2, PIK3CB, PIK3CA, CDK4, MYBL2, RRAS, MYB, KRAS, AKT1, NRAS, FZD6, IL2RG, TGFBR1, TERT, CDC16, PDGFRA, PPP3CA, PIK3CG, WNT10A, STAT5A, JAK3, PIK3R1, PIK3R3, POLE3, MRAS, ADCY5, CDC27, RAN, PRKACA, HLA-A, HLA-E, PPP3R1, ELK4, CHEK1, ANAPC10, ANAPC11, TCF3, POLE, GSK3B, POLB, SPI1, ITGB2, CREB1, TNFRSF1A, TP53, HLA-G, HLA-DPB1, JUN, TGFBR2, ITGAL, PIK3R2, FOSL1, CD3E, DLG1, VDAC3, ANAPC5, MAD2L1, ANAPC4, ANAPC2, CCND2, PTTG1, CALR, TNF, PTTG2, HLA-B, PPP3CB, CHUK, SLC25A5, PIK3CD, NFKB2, STAT5B, IL15RA, WNT1, NFATC3, CCND3, PCNA, FZD8, IKBKG, CDC26, VCAM1, ATF1, PPP3R2, BUB3, JAK1, HLA-F, PIK3R5, ATF4, EP300, ATF3, PPP3CC, ATF2, EGR2, CHEK2, HLA-DRB1, NFKB1, NFYB, FZD10, ADCY8, ATR, SMAD4, XPO1, NFATC4, MAP3K3	1481	256	6910	3.3352939314652263	1.90883379844269E-65	6.3627793281423E-66	9.596360795482417E-65
KEGG_PATHWAY	hsa05161:Hepatitis B	128	6.885422270037654	9.473290334452983E-67	CCND1, TBK1, PTK2B, ELK1, CREB3L4, TLR4, MMP9, MAPK10, NFATC2, TICAM2, CDKN1A, MAP2K2, HSPG2, CASP9, BCL2, RB1, E2F1, BAD, CASP8, NFKBIA, CCNE1, CCNA2, MAVS, TIRAP, STAT2, BAX, DDX58, RELA, MAPK9, MAP2K4, TLR2, CDKN1B, E2F3, TGFB1, MAPK8, IFNA8, MYD88, IKBKB, PRKCA, CREBBP, MAP2K1, IKBKE, TGFB2, IL6, IRF7, AKT3, NFATC1, AKT2, MAPK1, MYC, FOS, CREB3L2, YWHAZ, MAP3K1, CCNA1, MAPK3, CDK2, IRF3, CYCS, RAF1, PIK3CB, PIK3CA, CDK4, STAT4, FAS, KRAS, STAT3, AKT1, NRAS, TGFBR1, STAT1, CCNE2, SRC, PIK3CG, YWHAB, TICAM1, STAT6, STAT5A, PIK3R1, CREB3L1, CREB3L3, GRB2, PIK3R3, CREB3, CREB5, CDK6, IFIH1, IFNAR1, PRKCB, CREB1, FASLG, TP53, JUN, PIK3R2, PTEN, IFNA4, IFNA16, VDAC3, IFNA6, IFNA10, IFNA21, IFNA5, IFNA1, TNF, CHUK, PIK3CD, STAT5B, FADD, IFNA14, NFATC3, IFNA17, PCNA, IKBKG, JAK1, PIK3R5, ATF4, EP300, IFNB1, PRKCG, ATF2, EGR2, NFKB1, CASP10, ATF6B, SMAD4, NFATC4, CASP3, CXCL8	1481	145	6910	4.118745488835596	2.4630554869577757E-64	6.157638717394439E-65	1.2382622903797614E-63
KEGG_PATHWAY	hsa05205:Proteoglycans in cancer	150	8.068854222700377	7.66955039450032E-60	FZD4, CCND1, RRAS2, ELK1, CAV2, PRKACG, TLR4, MMP9, GPC1, MAPK12, RPS6, ARAF, WNT5B, FGF2, FZD2, MDM2, PDPK1, PLCG2, FZD5, CAMK2A, CDKN1A, CD63, FZD9, MAP2K2, PRKACB, HSPG2, SDC2, BRAF, PAK1, ITGB1, ROCK1, SOS1, FLNB, RHOA, CAMK2G, TWIST1, SOS2, MAPK14, TLR2, CAMK2B, CAV3, CAMK2D, TGFB1, ARHGEF1, CDC42, CBL, PRKCA, GPC3, ANK1, MAP2K1, TGFB2, ERBB4, ITPR1, ARHGEF12, CTNNB1, AKT3, ITGAV, ITGA2, AKT2, PTPN11, MAPK1, FZD7, MYC, MTOR, WNT3A, PLCE1, HIF1A, PLCG1, MAPK3, DCN, RAF1, RDX, PIK3CB, PTK2, PXN, MMP2, PIK3CA, ACTG1, RRAS, SDC4, FAS, KRAS, EGFR, STAT3, AKT1, NRAS, FZD6, ITGA5, IGF1, ITPR3, SRC, PIK3CG, ACTB, WNT10A, ANK2, CAV1, PPP1CA, PIK3R1, EZR, PTPN6, GRB2, PIK3R3, NUDT16L1, MRAS, MAPK11, PRKACA, TIMP3, MAPK13, SDC1, PPP1CB, MSN, CBLB, FLNA, PRKCB, PLAUR, ITGB3, RAC1, FASLG, TP53, IGF1R, KDR, ANK3, VEGFA, PIK3R2, PLAU, FN1, PPP1CC, RPS6KB1, MET, TNF, PIK3CD, HGF, ERBB2, WNT1, FRS2, THBS1, FZD8, PIK3R5, PRKCG, SLC9A1, TFAP4, FZD10, FLNC, GAB1, ESR1, CBLC, VTN, CASP3, ERBB3, CD44	1481	200	6910	3.49932478055368	1.994083102570083E-57	3.988166205140166E-58	1.0024938223563217E-56
KEGG_PATHWAY	hsa04510:Focal adhesion	142	7.638515330823023	3.7222939115875025E-49	CCND1, PDGFD, ELK1, CAV2, MAPK10, COL4A1, ITGA3, ITGB8, PDPK1, RAC2, COL2A1, ITGB7, ACTN4, PDGFB, BCL2, BRAF, SHC2, PAK1, COL6A3, TLN1, ITGB1, BAD, COL4A2, ROCK1, SOS1, PDGFA, FLNB, PDGFC, LAMA5, ITGA1, SHC3, SHC4, RHOA, MAPK9, EGF, SOS2, CAV3, MYL7, MAPK8, COL4A3, CDC42, PRKCA, MAP2K1, PAK6, CTNNB1, ACTN2, ACTN1, MYL12A, AKT3, TNXB, ITGAV, ITGA2, AKT2, MAPK1, RAC3, FYN, MYL10, RAP1A, RAP1B, COL1A1, RASGRF1, MAPK3, RAF1, MYL5, PIK3CB, PTK2, PXN, PIK3CA, ACTG1, IBSP, EGFR, AKT1, ITGA5, IGF1, SRC, PDGFRA, PIK3CG, ACTB, SPP1, COL4A5, RELN, CAV1, PPP1CA, PIK3R1, GRB2, PIK3R3, PAK3, SHC1, PPP1CB, GSK3B, VAV2, FLNA, FLT1, PRKCB, ITGB3, COL1A2, RAC1, MYL12B, COL4A6, IGF1R, JUN, KDR, VAV1, ILK, VWF, VEGFA, PGF, PIK3R2, PTEN, VEGFC, THBS2, FN1, VEGFB, MYL2, CCND2, PPP1CC, MET, BIRC3, PARVB, BCAR1, CRKL, BIRC2, PIK3CD, HGF, ERBB2, LAMC1, CCND3, THBS1, CRK, PIK3R5, PAK4, PRKCG, MYLPF, PAK2, LAMA1, FLNC, VASP, MYLK, MYL9, TNR, DOCK1, VTN, ITGA6	1481	206	6910	3.216207888923124	9.677964170127507E-47	1.6129940283545846E-47	4.865443812764902E-46
KEGG_PATHWAY	hsa04722:Neurotrophin signaling pathway	101	5.433028509951587	2.5350255004791178E-48	IRAK4, MAPK12, MAPK10, PSEN2, CALML5, CALM3, MAP3K5, PDPK1, PLCG2, CAMK2A, MAP2K2, BCL2, BRAF, MAPKAPK2, SHC2, BAD, NFKBIA, SOS1, IRAK2, FOXO3, YWHAE, BAX, SHC3, SHC4, RHOA, RELA, CAMK2G, MAPK9, SOS2, CAMK2B, MAPK14, CAMK2D, MAPK8, NGF, CDC42, IKBKB, ARHGDIA, MAP2K1, AKT3, MAGED1, PTPN11, AKT2, MAPK1, RAP1A, RAP1B, MAP3K1, PLCG1, MAPK3, RAF1, PIK3CB, PIK3CA, KRAS, TP73, RPS6KA5, MAP2K7, NRAS, AKT1, BDNF, NGFR, PIK3CG, IRS1, PIK3R1, CALML3, GRB2, PIK3R3, MAPK11, SHC1, MAPK13, GSK3B, ABL1, ZNF274, RAC1, TP53, FASLG, RPS6KA1, JUN, RPS6KA6, PIK3R2, PSEN1, RPS6KA2, MAPK7, MAP2K5, CRKL, CALML6, PIK3CD, IRAK1, NTRK1, FRS2, TRAF6, CRK, NFKBIE, ATF4, PIK3R5, RPS6KA3, NFKBIB, RIPK2, NFKB1, PRKCD, CAMK4, GAB1, MAP3K3	1481	120	6910	3.927020031510241	6.5910663012457065E-46	9.41580900177958E-47	3.313554606236641E-45
KEGG_PATHWAY	hsa04062:Chemokine signaling pathway	132	7.100591715976331	6.681009521128256E-48	ADCY9, PTK2B, PRKACG, CXCR4, ADCY2, ADCY1, PLCB4, GRK4, RAC2, CCL14, CXCR5, CCR10, CXCL5, PRKACB, GNB4, WASL, BRAF, SHC2, CCL5, ADCY7, PAK1, CCL2, NFKBIA, ROCK1, ADCY4, GNG13, SOS1, FOXO3, CXCL12, STAT2, SHC3, CCL1, SHC4, RHOA, RELA, SOS2, ARRB1, CDC42, PLCB1, IKBKB, MAP2K1, NCF1, CCL17, AKT3, GNG12, JAK2, AKT2, MAPK1, CXCL2, RAP1A, RAP1B, LYN, GNAI3, ADCY3, MAPK3, GRK5, GNG7, GNG3, ADCY6, RAF1, PIK3CB, GNG5, PTK2, PXN, PIK3CA, CCL26, KRAS, GNGT1, STAT3, AKT1, NRAS, PF4, STAT1, GNG4, SRC, GNG10, PPBP, PIK3CG, PLCB3, JAK3, PIK3R1, GRB2, PIK3R3, PREX1, CCL11, ADCY5, PRKACA, CCR3, GNAI1, SHC1, PLCB2, GSK3B, VAV2, RAC1, ITK, ARRB2, VAV1, CCL19, PIK3R2, CXCL1, GRK1, GNG2, GNAI2, CHUK, GNB3, CRKL, BCAR1, PIK3CD, GRK7, GNB2, STAT5B, HCK, GSK3A, IKBKG, CRK, GNB5, GRK6, PIK3R5, NFKBIB, GNG8, CCL4, PRKCD, NFKB1, ELMO1, ADCY8, CCL13, CCR5, CCR1, CCL3, CXCL8, CCL7, PRKCZ	1481	186	6910	3.311189039663697	1.7370624754933465E-45	2.171328094366683E-46	8.732807566969778E-45
KEGG_PATHWAY	hsa04014:Ras signaling pathway	147	7.907477138246369	3.963833316153972E-46	RASSF5, TBK1, PDGFD, RRAS2, ELK1, PRKACG, FGF10, MAPK10, FGF2, CALML5, CALM3, RAC2, PLCG2, INS, INSR, MAP2K2, PRKACB, PDGFB, GNB4, ANGPT2, SHC2, PAK1, BAD, HTR7, GNG13, SOS1, PDGFA, PDGFC, BCL2L1, SHC3, SHC4, RHOA, RELA, MAPK9, EGF, SOS2, NGF, MAPK8, BRAP, CDC42, PRKCA, IKBKB, GRIN1, EFNA1, MAP2K1, PAK6, RAB5B, FGF1, AKT3, GNG12, ZAP70, AKT2, PTPN11, FGFR2, MAPK1, ETS2, RAC3, RAP1A, RAP1B, FGF13, PLCE1, FGFR3, ETS1, RASGRF1, PLCG1, MAPK3, PLA2G10, PLD2, ANGPT4, GNG7, GNG3, RAF1, CSF1, PIK3CB, GNG5, PIK3CA, RRAS, NF1, GRIN2B, KRAS, EGFR, GNGT1, AKT1, FGF12, NRAS, FGF3, IGF1, GNG4, GNG10, NGFR, PDGFRA, PIK3CG, GRIN2A, PIK3R1, CALML3, GRB2, PIK3R3, MRAS, PRKACA, PAK3, SHC1, ANGPT1, REL, FGF7, FGFR4, FLT1, PRKCB, ABL1, RAC1, FASLG, FGF18, IGF1R, PLD1, KDR, VEGFA, PGF, PIK3R2, VEGFC, PLA2G2A, KITLG, VEGFB, CSF1R, MET, GNG2, CHUK, CALML6, GNB3, PIK3CD, HGF, GNB2, FOXO4, IKBKG, GNB5, GAB2, PIK3R5, PAK4, PRKCG, GNG8, PAK2, NFKB1, RAB5C, KIT, GAB1, RAB5A, ARF6, EFNA4, EFNA5	1481	226	6910	3.0348126415421297	1.0305966622000327E-43	1.1451074024444808E-44	5.181162138453387E-43
KEGG_PATHWAY	hsa04728:Dopaminergic synapse	103	5.540613232920926	9.048745738317599E-46	PPP2R2D, CREB3L4, PRKACG, MAPK12, MAPK10, GRIA2, GRIA3, PLCB4, PPP2R2C, CALML5, CALM3, CAMK2A, PRKACB, GNB4, GNG13, CLOCK, GRIA1, PPP2CA, CAMK2G, MAPK9, DRD2, CAMK2B, MAPK14, PPP2R5E, CAMK2D, MAPK8, PRKCA, PLCB1, CACNA1A, KCNJ9, ITPR1, AKT3, GNG12, AKT2, GNAL, FOS, CREB3L2, GNAI3, PPP2R5A, PPP2R3A, KIF5A, GNG7, PPP2R5B, GNG3, GNG5, GNAO1, GRIN2B, GNGT1, AKT1, ITPR3, PPP2R2A, PPP2CB, GNG4, GNG10, PPP2R1B, PPP2R1A, PPP3CA, PLCB3, GRIN2A, PPP1CA, CALML3, CREB3L1, CREB3L3, CREB3, PPP2R3C, CREB5, MAPK11, ADCY5, PPP2R2B, PRKACA, GNAI1, MAPK13, PLCB2, GNAS, PPP1CB, GSK3B, PRKCB, CREB1, PPP1CC, GNG2, GNAI2, PPP3CB, ARNTL, GNB3, CALML6, PPP2R5C, KCNJ6, PPP1R1B, GRIA4, GNB2, PPP2R5D, GSK3A, GNB5, ATF4, PPP3CC, PRKCG, GNAQ, CACNA1C, ATF2, GNG8, ATF6B, DRD3, DRD4	1481	128	6910	3.754483879135719	2.3526738919625757E-43	2.3526738919625755E-44	1.1827696848098605E-42
KEGG_PATHWAY	hsa04015:Rap1 signaling pathway	139	7.477138246369015	6.807071972448417E-45	RASSF5, ADCY9, PDGFD, FGF10, MAPK12, ADCY2, ADCY1, PLCB4, PFN1, FGF2, CALML5, CALM3, RAC2, CTNND1, INS, INSR, MAP2K2, PDGFB, BRAF, ANGPT2, ADCY7, TLN1, ITGB1, ADCY4, PDGFA, PDGFC, RHOA, EGF, DRD2, MAPK14, NGF, CDC42, MAGI1, MAP2K6, PLCB1, PRKCA, GRIN1, EFNA1, MAP2K1, MAGI3, FGF1, CTNNB1, AKT3, LCP2, PRKCI, AKT2, FGFR2, MAPK1, RAC3, ITGAM, MAP2K3, RAP1A, RAP1B, FGF13, GNAI3, PLCE1, ADCY3, FGFR3, PLCG1, MAPK3, ANGPT4, ADCY6, RAF1, CSF1, DOCK4, PIK3CB, GNAO1, PIK3CA, ACTG1, RRAS, GRIN2B, KRAS, EGFR, CNR1, AKT1, FGF12, NRAS, RAPGEF6, FGF3, IGF1, SRC, NGFR, PDGFRA, PIK3CG, ACTB, PLCB3, GRIN2A, PIK3R1, CDH1, CALML3, PIK3R3, MRAS, MAPK11, ADCY5, GNAI1, MAPK13, ANGPT1, PLCB2, GNAS, RGS14, FGF7, FGFR4, FLT1, PRKCB, ITGB2, ITGB3, RAC1, IGF1R, FGF18, KDR, ITGAL, PRKD2, VEGFA, PGF, PIK3R2, F2R, VEGFC, KITLG, VEGFB, CSF1R, MET, ADORA2A, GNAI2, CALML6, BCAR1, CRKL, PIK3CD, HGF, THBS1, CRK, PIK3R5, PRKCG, GNAQ, KIT, ADCY8, VASP, EFNA4, EFNA5, PRKCZ	1481	210	6910	3.088292980933089	1.7698387128365883E-42	1.6089442843968985E-43	8.897584929630016E-42
KEGG_PATHWAY	hsa04915:Estrogen signaling pathway	87	4.679935449166218	1.214226273653795E-44	ITPR3, ADCY9, SRC, CREB3L4, PRKACG, PIK3CG, MMP9, PLCB3, ADCY1, ADCY2, PLCB4, CALML5, HSPA8, CALM3, PIK3R1, CREB3L1, CALML3, CREB3L3, GRB2, PIK3R3, CREB3, CREB5, ADCY5, PRKACA, GNAI1, MAP2K2, PRKACB, SHC1, SHC2, ADCY7, PLCB2, GNAS, ADCY4, SOS1, CREB1, GABBR2, JUN, HSP90AB1, ESR2, SHC3, SHC4, GABBR1, SOS2, PIK3R2, HSPA1L, PLCB1, MAP2K1, KCNJ9, ITPR1, GNAI2, AKT3, HSP90AA1, CALML6, PIK3CD, KCNJ6, HSP90B1, NOS3, AKT2, MAPK1, OPRM1, FOS, HSPA6, CREB3L2, GNAI3, ADCY3, PIK3R5, ATF4, GNAQ, ATF2, HSPA2, MAPK3, PRKCD, ADCY6, ADCY8, RAF1, ESR1, ATF6B, PIK3CB, GNAO1, MMP2, HSPA1A, PIK3CA, KRAS, EGFR, SP1, NRAS, AKT1	1481	99	6910	4.1002189347901705	3.1569883114998666E-42	2.6308235929165558E-43	1.5871260708496478E-41
KEGG_PATHWAY	hsa05215:Prostate cancer	80	4.303388918773534	1.8404411201016247E-43	CCND1, IGF1, TCF7, CCNE2, PDGFD, CREB3L4, PDGFRA, PIK3CG, ARAF, FOXO1, PIK3R1, CREB3L1, CREB3L3, GRB2, PIK3R3, PDPK1, MDM2, CREB3, CREB5, INS, CDKN1A, LEF1, MAP2K2, PDGFB, CASP9, BCL2, BRAF, TCF7L2, RB1, TCF7L1, E2F1, GSK3B, BAD, NFKBIA, CCNE1, SOS1, PDGFA, PDGFC, CREB1, TP53, IGF1R, HSP90AB1, RELA, EGF, SOS2, PIK3R2, PTEN, E2F3, CDKN1B, IKBKB, MAP2K1, CREBBP, CTNNB1, CHUK, AR, AKT3, HSP90AA1, PIK3CD, HSP90B1, ERBB2, AKT2, MAPK1, FGFR2, MTOR, IKBKG, CREB3L2, PIK3R5, EP300, ATF4, MAPK3, NKX3-1, NFKB1, CDK2, RAF1, PIK3CB, PIK3CA, KRAS, EGFR, NRAS, AKT1	1481	88	6910	4.241605794610521	4.785146912264224E-41	3.68088224020325E-42	2.405657122528932E-40
KEGG_PATHWAY	hsa04010:MAPK signaling pathway	154	8.284023668639055	1.9189150297873693E-42	ELK1, RRAS2, MAP3K14, PRKACG, MAPK12, DUSP1, FGF10, MAPK10, FGF2, MAP3K7, HSPA8, IL1R1, MAP3K5, RAC2, MAP2K2, PRKACB, PDGFB, BRAF, MAPKAPK2, DUSP3, PAK1, MAP3K4, PDGFA, SOS1, FLNB, PPP5C, RELB, MAPK9, RELA, MAP2K4, EGF, SOS2, MAPK14, TAB2, ARRB1, TGFB1, NGF, MAPK8, IL1B, HSPA1L, CDC42, MAP2K6, PRKCA, IKBKB, MAP3K12, IL1R2, MAP2K1, CACNA1A, TGFB2, FGF1, GNG12, AKT3, NFATC1, AKT2, MAPK1, FGFR2, RAC3, MOS, MYC, SRF, FOS, MAP2K3, HSPA6, RAP1B, RAP1A, RPS6KA4, MAPT, FGF13, MAP3K1, FGFR3, MAP4K1, RASGRF1, MAPK3, TRAF2, RAF1, MEF2C, MAP3K2, RRAS, FAS, NF1, KRAS, RPS6KA5, EGFR, MAP2K7, AKT1, NRAS, FGF12, BDNF, TGFBR1, FGF3, GADD45B, PDGFRA, PPP3CA, STK3, GRB2, MAPK8IP2, MAPK11, MRAS, PRKACA, PPP3R1, ELK4, MAPK13, ECSIT, FGFR4, FGF7, FLNA, PRKCB, MAP3K11, RAC1, TNFRSF1A, FASLG, TP53, FGF18, RPS6KA1, JUN, TGFBR2, ARRB2, STMN1, RPS6KA6, DDIT3, HSPB1, RPS6KA2, TNF, MAPK7, MAP2K5, PPP3CB, CHUK, CRKL, NFKB2, NTRK1, JUND, NFATC3, MAPKAPK5, NR4A1, TRAF6, CRK, IKBKG, MAP3K8, PPP3R2, ATF4, RPS6KA3, PPP3CC, PRKCG, HSPA2, ATF2, CACNA1C, PAK2, NFKB1, TAB1, FLNC, HSPA1A, IL1A, CASP3, MAP3K3	1481	255	6910	2.817756947478519	4.9891790774471604E-40	3.563699341033686E-41	2.5082310748854086E-39
KEGG_PATHWAY	hsa05142:Chagas disease (American trypanosomiasis)	88	4.733727810650888	2.2089436516521796E-42	PPP2R2D, PPP2R2A, TGFBR1, PPP2CB, IRAK4, PPP2R1B, PPP2R1A, PIK3CG, TLR4, MAPK12, PLCB3, MAPK10, TICAM1, SMAD3, ADCY1, PLCB4, PPP2R2C, PIK3R1, PIK3R3, MAPK11, PPP2R2B, GNAI1, MAPK13, GNA11, CCL5, CFLAR, PLCB2, GNAS, CASP8, CCL2, NFKBIA, TLR9, FASLG, TNFRSF1A, JUN, TGFBR2, PPP2CA, RELA, MAPK9, MAP2K4, PIK3R2, TLR2, MAPK14, CD3E, TGFB1, MAPK8, IL1B, CD247, MYD88, PLCB1, IKBKB, GNA15, CALR, TNF, NOS2, TGFB2, IL6, GNAI2, CHUK, AKT3, PIK3CD, IRAK1, AKT2, FADD, IL10, MAPK1, GNAL, FOS, IL12A, TRAF6, IKBKG, GNAI3, IFNG, PIK3R5, IFNB1, GNAQ, MAPK3, NFKB1, BDKRB2, IL2, SMAD2, PIK3CB, GNAO1, PIK3CA, FAS, CCL3, CXCL8, AKT1	1481	104	6910	3.9479561626759465	5.743253494295667E-40	3.8288356628637776E-41	2.8873300921296036E-39
KEGG_PATHWAY	hsa04380:Osteoclast differentiation	99	5.325443786982249	1.1147450640016674E-39	JUNB, MAP3K14, TNFRSF11A, TNFSF11, MAPK12, MAPK10, SOCS1, NFATC2, MAP3K7, IL1R1, PLCG2, SIRPA, NFKBIA, BLNK, RELB, STAT2, MAPK9, RELA, MAPK14, TAB2, TGFB1, IL1B, MAPK8, LCK, MAP2K6, IKBKB, MAP2K1, NCF1, TGFB2, AKT3, LCP2, NFATC1, SYK, AKT2, MAPK1, FYN, PPARG, FOS, SQSTM1, MAPK3, TRAF2, CSF1, NCF4, PIK3CB, PIK3CA, IFNAR2, TYROBP, MAP2K7, AKT1, TGFBR1, LILRB4, STAT1, PIK3CG, PPP3CA, BTK, FHL2, PIK3R1, PIK3R3, GRB2, MAPK11, MAPK13, PPP3R1, IFNAR1, SPI1, ITGB3, CREB1, RAC1, TNFRSF1A, FOSL2, JUN, TGFBR2, PIK3R2, FOSB, SOCS3, FOSL1, CSF1R, TNF, MITF, PPP3CB, CHUK, TEC, PIK3CD, NFKB2, JUND, TRAF6, IKBKG, IFNG, GAB2, JAK1, PPP3R2, PIK3R5, PPP3CC, IFNB1, TAB1, NFKB1, CAMK4, TYK2, IL1A, CYLD	1481	131	6910	3.52603718345867	2.8983371664043354E-37	1.8114607290027096E-38	1.4570932879784305E-36
KEGG_PATHWAY	hsa04114:Oocyte meiosis	88	4.733727810650888	3.117323499242805E-39	ITPR3, IGF1, ADCY9, PPP2CB, CDC16, ANAPC1, CCNE2, PPP2R1B, CDC20, PPP2R1A, PPP3CA, PRKACG, YWHAB, ADCY1, ADCY2, PPP1CA, CALML5, CALM3, PLK1, CALML3, ESPL1, CAMK2A, ADCY5, CUL1, CDC27, INS, PRKACA, PKMYT1, SMC3, PRKACB, PPP3R1, CDC25C, FBXW11, PGR, ANAPC10, ANAPC11, ADCY7, PPP1CB, CCNE1, ADCY4, IGF1R, RPS6KA1, YWHAE, PPP2CA, SMC1A, RPS6KA6, CAMK2G, CAMK2B, PPP2R5E, CAMK2D, ANAPC5, ANAPC4, MAD2L1, ANAPC2, PPP1CC, BTRC, PTTG1, RPS6KA2, MAP2K1, CDK1, PTTG2, ITPR1, YWHAG, PPP3CB, AR, PPP2R5C, CALML6, SKP1, RBX1, MAPK1, PPP2R5D, MAD2L2, MOS, CDC26, YWHAZ, SMC1B, PPP2R5A, ADCY3, PPP3R2, BUB1, RPS6KA3, PPP3CC, MAPK3, CDK2, PPP2R5B, ADCY6, ADCY8, YWHAH	1481	109	6910	3.7668572561311784	8.105041098031293E-37	4.767671234136055E-38	4.074681551760907E-36
KEGG_PATHWAY	hsa04024:cAMP signaling pathway	127	6.831629908552986	8.510599798255165E-39	ADCY9, RRAS2, PDE4A, CREB3L4, PRKACG, MAPK10, GRIA2, GRIA3, HTR1E, ADCY1, ADCY2, CALML5, CALM3, NPY, GRIN2D, RAC2, CAMK2A, CHRM2, MAP2K2, PRKACB, BRAF, ADCY7, PAK1, ATP2B4, BAD, NFKBIA, ROCK1, ADCY4, RYR2, GRIA1, GABBR2, RHOA, RELA, CAMK2G, MAPK9, DRD2, CAMK2B, CAMK2D, MAPK8, GRIN1, CREBBP, MAP2K1, AKT3, CFTR, ATP1A2, NFATC1, AKT2, MAPK1, RAC3, GLI1, FOS, CREB3L2, RAP1A, RAP1B, HTR1D, GNAI3, ADCY3, PLCE1, GLI3, PLN, HTR1B, MAPK3, PLD2, ADCY6, RAF1, ADRB2, PIK3CB, PDE4B, PIK3CA, FSHR, RRAS, GRIN2B, AKT1, BDNF, PIK3CG, GRIN2A, PPP1CA, PIK3R1, ADCYAP1R1, CALML3, CREB3L1, CREB3L3, PIK3R3, CREB3, CREB5, FXYD2, ADCY5, PRKACA, GNAI1, PPARA, ATP1A1, ATP1B1, GNAS, PPP1CB, ORAI1, VAV2, CREB1, RAC1, JUN, PLD1, VAV1, GABBR1, PIK3R2, F2R, PPP1CC, ADRB1, ADORA2A, GNAI2, NPR1, CALML6, PIK3CD, GRIA4, PPP1R1B, HTR1F, FSHB, PIK3R5, EP300, CACNA1C, SLC9A1, NFKB1, CAMK4, ADCY8, TSHR, HTR1A, MYL9, PDE3B, ATP1A3	1481	198	6910	2.99268853286409	2.212755947546343E-36	1.2293088597479683E-37	1.112428145516295E-35
KEGG_PATHWAY	hsa05162:Measles	99	5.325443786982249	1.0423446206992328E-38	CCND1, TBK1, IRAK4, TLR4, MAP3K7, HSPA8, NFKBIA, CCNE1, MAVS, TLR9, IL2RB, STAT2, DDX58, RELA, IL2RA, TLR2, TAB2, CDKN1B, IL1B, IFNA8, MYD88, HSPA1L, BBC3, IKBKE, IL6, IRF7, AKT3, JAK2, AKT2, FYN, IL12A, HSPA6, EIF2AK2, CDK2, IRF3, IL2, PIK3CB, CDK4, PIK3CA, FAS, IFNAR2, EIF2S1, TP73, AKT1, STAT3, IL2RG, STAT1, CCNE2, PIK3CG, STAT5A, JAK3, PIK3R1, PIK3R3, EIF2AK1, EIF2AK4, CDK6, IFIH1, GSK3B, MSN, IFNAR1, CD209, TP53, FASLG, PIK3R2, IFNA4, IFNA16, CD3E, IFNA6, IFNA10, CSNK2A2, TNFRSF10B, IFNA21, IFNA5, CCND2, IFNA1, CSNK2B, CSNK2A1, CHUK, PIK3CD, IRAK1, STAT5B, IFNA14, IFNA17, CCND3, TRAF6, TNFRSF10A, IFNG, JAK1, PIK3R5, NFKBIB, IFNB1, HSPA2, NFKB1, PRKCQ, EIF2AK3, TYK2, HSPA1A, IL1A, CLEC4M	1481	133	6910	3.473014067917938	2.7100960138180054E-36	1.4263663230621081E-37	1.3624580180953405E-35
KEGG_PATHWAY	hsa04668:TNF signaling pathway	86	4.626143087681549	1.2193704540438046E-38	JUNB, MAP3K14, CREB3L4, PIK3CG, MMP9, MAPK12, SELE, MAPK10, MAP3K7, PIK3R1, CREB3L1, CREB3L3, PIK3R3, MAP3K5, CREB3, CREB5, MAPK11, MMP14, CASP7, ITCH, MAPK13, CCL5, CFLAR, CASP8, CCL2, PTGS2, NFKBIA, CREB1, TNFRSF1A, JUN, TRADD, RELA, MAPK9, MAP2K4, PIK3R2, MAPK14, TAB2, SOCS3, MAPK8, IL1B, CXCL1, MAP2K6, IKBKB, TNF, BIRC3, MAP2K1, IL6, TRAF5, CHUK, AKT3, RIPK1, BIRC2, PIK3CD, AKT2, FADD, DNM1L, MAPK1, CXCL2, FOS, IKBKG, MAP2K3, TRAF3, CREB3L2, RPS6KA4, MAP3K8, VCAM1, PIK3R5, ATF4, ATF2, MAPK3, TAB1, NFKB1, TRAF2, CASP10, CSF1, ATF6B, PIK3CB, MMP3, PIK3CA, FAS, CEBPB, CASP3, RPS6KA5, TNFRSF1B, MAP2K7, AKT1	1481	106	6910	3.785433095944861	3.170363180513892E-36	1.585181590256946E-37	1.5938500752525255E-35
KEGG_PATHWAY	hsa04914:Progesterone-mediated oocyte maturation	76	4.088219472834857	1.59961488015186E-38	CCNB2, IGF1, ADCY9, CDC16, ANAPC1, PRKACG, PIK3CG, MAPK12, ARAF, MAPK10, ADCY1, ADCY2, PLK1, PIK3R1, PIK3R3, MAPK11, ADCY5, CDC27, CDC25A, INS, PRKACA, PKMYT1, GNAI1, PRKACB, CDC25C, MAPK13, BRAF, PGR, ANAPC10, ANAPC11, ADCY7, FZR1, ADCY4, CCNA2, IGF1R, RPS6KA1, CCNB1, HSP90AB1, RPS6KA6, MAPK9, MAPK14, PIK3R2, MAPK8, ANAPC5, MAD2L1, ANAPC4, ANAPC2, RPS6KA2, MAP2K1, CDK1, GNAI2, AKT3, HSP90AA1, PIK3CD, AKT2, MAPK1, MAD2L2, MOS, CDC26, GNAI3, ADCY3, MAD1L1, PIK3R5, BUB1, RPS6KA3, CCNA1, MAPK3, CDK2, ADCY6, ADCY8, RAF1, PDE3B, PIK3CB, PIK3CA, KRAS, AKT1	1481	87	6910	4.0758418899935585	4.158998688394836E-36	1.980475565902303E-37	2.090870980717983E-35
KEGG_PATHWAY	hsa04660:T cell receptor signaling pathway	84	4.518558364712211	4.719776199461244E-38	MAP3K14, PPP3CA, PIK3CG, MAPK12, NFATC2, MAP3K7, PIK3R1, PTPN6, GRB2, PIK3R3, PDPK1, MAPK11, PAK3, MAP2K2, PPP3R1, MAPK13, PAK1, PTPRC, GSK3B, CBLB, NFKBIA, VAV2, SOS1, IL5, ITK, JUN, VAV1, RHOA, RELA, SOS2, PIK3R2, MAPK14, CD3E, DLG1, CD247, LCK, CDC42, BCL10, CBL, CD4, IKBKB, TNF, MAP2K1, PAK6, MALT1, PPP3CB, CHUK, TEC, AKT3, LCP2, PIK3CD, ZAP70, NFATC1, AKT2, IL10, MAPK1, FYN, NFATC3, FOS, IKBKG, NFKBIE, MAP3K8, IFNG, PPP3R2, PIK3R5, NFKBIB, PAK4, PPP3CC, PLCG1, MAPK3, PAK2, NFKB1, RAF1, IL2, PRKCQ, CBLC, PIK3CB, CDK4, PIK3CA, KRAS, NCK1, MAP2K7, NRAS, AKT1	1481	103	6910	3.8050910235146813	1.2271418118599235E-35	5.577917326636016E-37	6.169261872582768E-35
KEGG_PATHWAY	hsa05220:Chronic myeloid leukemia	67	3.604088219472835	8.289218543681483E-38	CCND1, TGFBR1, HDAC2, PIK3CG, CDKN2A, ARAF, STAT5A, PIK3R1, BCR, GRB2, PIK3R3, MDM2, CDK6, CDKN1A, MAP2K2, SHC1, BRAF, RB1, SHC2, E2F1, BAD, CBLB, NFKBIA, RUNX1, ABL1, SOS1, TP53, BCL2L1, TGFBR2, SHC3, SHC4, RELA, SOS2, PIK3R2, TGFB1, E2F3, CDKN1B, CBL, IKBKB, MAP2K1, TGFB2, CHUK, HDAC1, AKT3, CRKL, CTBP1, PIK3CD, STAT5B, AKT2, PTPN11, MAPK1, MYC, CRK, IKBKG, GAB2, PIK3R5, MAPK3, NFKB1, RAF1, CBLC, PIK3CB, SMAD4, CDK4, PIK3CA, KRAS, NRAS, AKT1	1481	72	6910	4.341754820316603	2.1551968213571857E-35	9.370420962422546E-37	1.0834912028429994E-34
KEGG_PATHWAY	hsa05169:Epstein-Barr virus infection	122	6.56266810112964	2.5483087343854068E-37	TBK1, MAP3K14, SNW1, PRKACG, MAPK12, MAPK10, MAP3K7, HSPA8, RBPJL, MDM2, PLCG2, CDKN1A, PRKACB, BCL2, RB1, NFKBIA, CCNA2, USP7, RELB, HDAC5, YWHAE, DDX58, RELA, MAPK9, MAP2K4, MAPK14, TAB2, CDKN1B, MAPK8, PSMC2, GTF2B, HSPA1L, MAP2K6, IKBKB, CREBBP, TRAF5, AKT3, AKT2, SYK, IL10, PSMC3, MYC, MAP2K3, TRAF3, HSPA6, LYN, YWHAZ, CD40, NCOR2, TBP, EIF2AK2, CCNA1, PLCG1, TBPL1, CDK2, TRAF2, IRF3, PIK3CB, PIK3CA, YWHAH, MAP2K7, STAT3, AKT1, PSMD3, HDAC2, PTMA, PIK3CG, YWHAB, JAK3, PIK3R1, PIK3R3, EIF2AK1, MAPK11, EIF2AK4, RAN, PRKACA, HLA-A, HLA-E, MAPK13, GSK3B, SPI1, TP53, HLA-G, JUN, ITGAL, TRADD, PSMD7, PIK3R2, HSPB1, CSNK2A2, CSNK2B, CDK1, CSNK2A1, HLA-B, YWHAG, CHUK, HDAC1, RIPK1, PIK3CD, NFKB2, VIM, IRAK1, IL10RB, TRAF6, IKBKG, NFKBIE, IFNG, JAK1, HLA-F, PIK3R5, EP300, NFKBIB, HSPA2, ATF2, TAB1, NFKB1, PSMD13, EIF2AK3, TYK2, HSPA1A, XPO1, CD44	1481	190	6910	2.995913145456484	6.625602709402057E-35	2.7606677955841908E-36	3.330917240611555E-34
KEGG_PATHWAY	hsa04620:Toll-like receptor signaling pathway	84	4.518558364712211	2.580805066020967E-36	TBK1, STAT1, IRAK4, PIK3CG, TLR4, MAPK12, MAPK10, TICAM1, SPP1, MAP3K7, PIK3R1, PIK3R3, MAPK11, TICAM2, TOLLIP, MAP2K2, IRF5, MAPK13, CCL5, CASP8, NFKBIA, IFNAR1, TLR9, RAC1, JUN, TIRAP, RELA, MAPK9, MAP2K4, PIK3R2, MAPK14, TLR2, TAB2, IFNA4, TLR1, IFNA16, IFNA6, MAPK8, IL1B, IFNA8, IFNA10, MYD88, IFNA21, IFNA5, IFNA1, MAP2K6, IKBKB, TNF, MAP2K1, IKBKE, IRF7, IL6, CHUK, RIPK1, AKT3, PIK3CD, IRAK1, AKT2, FADD, MAPK1, IFNA14, IFNA17, FOS, IL12A, TRAF6, IKBKG, MAP2K3, TRAF3, MAP3K8, PIK3R5, CD40, IFNB1, CCL4, MAPK3, TAB1, NFKB1, IRF3, PIK3CB, PIK3CA, IFNAR2, CCL3, MAP2K7, CXCL8, AKT1	1481	106	6910	3.69739976813219	6.710093171654514E-34	2.684037268661806E-35	3.373393487638046E-33
KEGG_PATHWAY	hsa04910:Insulin signaling pathway	98	5.27165142549758	1.8280598860213228E-35	PHKB, ELK1, TSC2, PRKACG, RPS6, MAPK10, ARAF, SOCS1, CALML5, CALM3, RHOQ, SOCS4, PDPK1, IRS4, INS, PPP1R3A, INSR, MAP2K2, PRKACB, BRAF, SHC2, BAD, PPP1R3E, SOS1, SHC3, SHC4, MAPK9, SOS2, SOCS2, MAPK8, CBL, IKBKB, MAP2K1, PRKAR2A, PRKAR1A, AKT3, PRKCI, PTPRF, PYGM, AKT2, MAPK1, PYGB, MTOR, GYS2, PRKAA1, FASN, MAPK3, PTPN1, IRS2, RAF1, PIK3CB, PIK3CA, KRAS, NRAS, AKT1, PHKA2, PIK3CG, PYGL, FOXO1, IRS1, INPPL1, PPP1CA, PIK3R1, CALML3, SREBF1, PIK3R3, GRB2, PPP1R3F, RHEB, PRKACA, GYS1, SHC1, PPP1CB, GSK3B, CBLB, TSC1, PIK3R2, SOCS3, PPP1CC, RPS6KB1, TRIP10, PPP1R3B, PPP1R3C, CRKL, CALML6, PIK3CD, CRK, PIK3R5, PPP1R3D, EIF4EBP1, PCK1, EIF4E, SLC2A4, PHKG1, CBLC, PDE3B, PHKG2, PRKCZ	1481	138	6910	3.313370323616045	4.752955703655439E-33	1.8280598860213227E-34	2.3894735002300937E-32
KEGG_PATHWAY	hsa05164:Influenza A	113	6.078536847767617	3.182552522403302E-35	TBK1, IRAK4, TLR4, MAPK12, MAPK10, FDPS, HSPA8, HLA-DMB, MAP2K2, CASP9, CCL5, CCL2, NFKBIA, NLRP3, MAVS, HLA-DRA, STAT2, DDX58, RELA, MAPK9, MAP2K4, MAPK14, IL1B, MAPK8, IFNA8, CASP1, MYD88, HSPA1L, MAP2K6, IKBKB, PRKCA, CREBBP, MAP2K1, IKBKE, IL6, IRF7, AKT3, JAK2, AKT2, MAPK1, IL12A, MAP2K3, DNAJC3, HSPA6, EIF2AK2, MAPK3, IRF3, CYCS, RAF1, PIK3CB, PIK3CA, ACTG1, FAS, IFNAR2, EIF2S1, MAP2K7, AKT1, STAT1, ACTB, PIK3CG, TICAM1, PIK3R1, PIK3R3, EIF2AK1, MAPK11, EIF2AK4, IFIH1, MAPK13, GSK3B, IFNAR1, PRKCB, FASLG, TNFRSF1A, HLA-DPB1, JUN, PIK3R2, IFNA4, IFNA16, SOCS3, IFNA6, IFNA10, TNFRSF10B, IFNA21, IFNA5, IFNA1, TNF, DNAJB1, RSAD2, PIK3CD, KPNA2, IFNA14, IFNA17, TNFRSF10A, PABPN1, IFNG, CIITA, JAK1, PIK3R5, EP300, NFKBIB, IFNB1, ATF2, HSPA2, HLA-DRB1, NFKB1, NUP98, EIF2AK3, TYK2, HSPA1A, XPO1, IL1A, CXCL8, PML	1481	174	6910	3.0300666682188955	8.274636558248585E-33	3.0646802067587354E-34	4.1599429939487387E-32
KEGG_PATHWAY	hsa04012:ErbB signaling pathway	73	3.9268423883808503	1.3547621377019053E-34	SRC, ELK1, PIK3CG, ARAF, MAPK10, STAT5A, PIK3R1, GRB2, PIK3R3, PLCG2, CAMK2A, CDKN1A, PAK3, MAP2K2, SHC1, BRAF, SHC2, PAK1, GSK3B, BAD, CBLB, ABL1, PRKCB, SOS1, JUN, SHC3, SHC4, MAPK9, CAMK2G, MAP2K4, EGF, SOS2, PIK3R2, CAMK2B, CAMK2D, CDKN1B, MAPK8, RPS6KB1, CBL, PRKCA, MAP2K1, PAK6, ERBB4, AKT3, CRKL, PIK3CD, STAT5B, ERBB2, AKT2, MAPK1, MYC, MTOR, CRK, PIK3R5, PAK4, PRKCG, PLCG1, EIF4EBP1, MAPK3, PAK2, GAB1, RAF1, CBLC, PTK2, PIK3CB, PIK3CA, ERBB3, KRAS, NCK1, EGFR, MAP2K7, NRAS, AKT1	1481	87	6910	3.914953394335918	3.5223815580249535E-32	1.2579934135803408E-33	1.7708217613151089E-31
KEGG_PATHWAY	hsa04713:Circadian entrainment	77	4.142011834319527	1.66559063901907E-34	RASD1, ITPR3, ADCY9, PRKG2, GNG4, GNG10, PRKACG, NOS1AP, PLCB3, GRIA2, GRIA3, GRIN2A, ADCY1, ADCY2, PLCB4, CALML5, ADCYAP1R1, CALM3, CALML3, GRIN2D, CAMK2A, ADCY5, PRKACA, GNAI1, PRKACB, PER3, GNB4, ADCY7, PLCB2, GNAS, ADCY4, GNG13, PRKCB, RYR2, CREB1, GRIA1, CAMK2G, CAMK2B, CAMK2D, PRKCA, PLCB1, GRIN1, KCNJ9, MTNR1B, ITPR1, GNG2, GNAI2, GNG12, CALML6, PER2, GNB3, KCNJ6, GRIA4, GNB2, NOS1, MAPK1, FOS, GNAI3, GNB5, ADCY3, PRKCG, GNG8, CACNA1C, GNAQ, MTNR1A, MAPK3, PRKG1, GNG7, PER1, ADCY6, ADCY8, GNG3, GNG5, GNAO1, GRIN2B, RPS6KA5, GNGT1	1481	95	6910	3.781726429510644	4.330535661449582E-32	1.4932881591205454E-33	2.1771084878567012E-31
KEGG_PATHWAY	hsa04630:Jak-STAT signaling pathway	100	5.3792361484669176	1.7745930055751441E-34	CCND1, CSF2RB, SOCS1, SOCS7, SOCS4, IL4R, PIAS4, SOS1, CISH, LIFR, BCL2L1, IL12RB1, IL2RB, STAT2, IL3RA, IL2RA, SOS2, SOCS2, IFNA8, IL9R, CNTFR, IL21R, IL21, CREBBP, IL6, AKT3, JAK2, IL12RB2, STAM2, PTPN11, AKT2, IL10, MYC, IL12A, STAM, CRLF2, IL13RA1, IL2, OSMR, PIK3CB, PIK3CA, STAT4, IFNAR2, IL6ST, AKT1, STAT3, PIM1, IL2RG, STAT1, IL22RA2, IL13RA2, IL11, PIK3CG, STAT6, SOCS5, STAT5A, JAK3, PIK3R1, PTPN6, PIK3R3, GRB2, PIAS3, CSF3R, CSH2, PIAS2, IFNAR1, IL5, IFNLR1, IL5RA, IFNL1, PIK3R2, IFNA4, IFNA16, PIAS1, SOCS3, IFNA6, IFNA10, PRL, IFNA21, IFNA5, IFNA1, CCND2, GHR, IL7R, PIK3CD, STAT5B, IFNA14, IL15RA, IL10RB, IFNA17, CCND3, IFNG, JAK1, EP300, PIK3R5, IFNB1, IFNL3, PRLR, EPOR, TYK2	1481	145	6910	3.217769913152809	4.6139418144953747E-32	1.5379806048317914E-33	2.3195864604547325E-31
KEGG_PATHWAY	hsa05152:Tuberculosis	113	6.078536847767617	3.350022027007357E-34	IRAK4, TLR4, MAPK12, MAPK10, CALML5, MRC1, CALM3, CAMK2A, HLA-DMB, CASP9, CTSS, RFXANK, BCL2, BAD, CASP8, IRAK2, TLR9, HLA-DRA, CD74, TIRAP, BAX, RHOA, RELA, CAMK2G, MAPK9, BID, TLR2, CAMK2B, MAPK14, TGFB1, CAMK2D, IL1B, MAPK8, IFNA8, MYD88, CREBBP, NOS2, IL6, TGFB2, MALT1, RAB5B, ARHGEF12, AKT3, JAK2, SYK, PLA2R1, AKT2, IL10, MAPK1, ITGAM, IL12A, MAPK3, CEBPG, CYCS, RAF1, CEBPB, AKT1, STAT1, SRC, PPP3CA, CALML3, MAPK11, PPP3R1, MAPK13, CD209, ITGB2, HSPA9, CREB1, TNFRSF1A, HLA-DPB1, HSPD1, PIK3C3, TRADD, TLR1, IFNA4, IFNA16, IFNA6, IFNA10, IFNA21, IFNA5, IFNA1, BCL10, TNF, PPP3CB, ATP6V0A1, CALML6, IRAK1, FADD, IFNA14, IL10RB, IFNA17, TRAF6, RFX5, IFNG, CIITA, PPP3R2, JAK1, EP300, PPP3CC, IFNB1, VDR, RIPK2, HLA-DRB1, NFKB1, RAB7A, NFYB, CASP10, RAB5C, RAB5A, IL1A, CASP3, CLEC4M, NFYA	1481	177	6910	2.978709606045694	8.710057270219128E-32	2.8096958936190736E-33	4.378843887955548E-31
KEGG_PATHWAY	hsa04810:Regulation of actin cytoskeleton	125	6.724045185583647	3.635577485496919E-33	PDGFD, RRAS2, FGF10, ARAF, CFL1, ITGA3, PFN1, FGF2, ITGB8, RAC2, APC, ITGB7, CHRM4, CHRM2, INS, ACTN4, MAP2K2, PDGFB, WASL, BRAF, PAK1, ITGB1, ROCK1, ARPC5, PDGFA, SOS1, PDGFC, GNA13, ITGA1, RHOA, ITGAD, EGF, SOS2, BDKRB1, MYL7, ARHGEF1, CDC42, MAP2K1, PAK6, ARHGEF12, FGF1, ACTN2, ACTN1, MYL12A, GNG12, ITGAV, ITGA2, FGFR2, MAPK1, RAC3, MOS, ITGAM, MYL10, FGF13, FGFR3, ARPC1B, MAPK3, ARHGEF7, BDKRB2, RAF1, RDX, GSN, MYL5, PIK3CB, PTK2, PXN, PIK3CA, ACTG1, FGD3, RRAS, KRAS, EGFR, FGF12, NRAS, IQGAP2, FGF3, ITGA5, SRC, PDGFRA, PIK3CG, ACTB, WASF2, PPP1CA, PIK3R1, EZR, PIK3R3, TMSB4X, LIMK1, MRAS, GIT1, PAK3, F2, PPP1CB, MSN, VAV2, FGF7, SSH1, FGFR4, ITGB2, ITGB3, MYL12B, RAC1, FGF18, VAV1, ITGAL, PIK3R2, F2R, LIMK2, FN1, MYL2, PPP1CC, BCAR1, CRKL, PIK3CD, ARHGEF6, CRK, PIK3R5, PAK4, MYLPF, SLC9A1, PAK2, WASF1, MYLK, MYL9, DOCK1, ITGA6	1481	211	6910	2.7640796054926384	9.452501462291989E-31	2.9539067069662464E-32	4.7520959931652465E-30
KEGG_PATHWAY	hsa05168:Herpes simplex infection	114	6.132329209252286	4.607678275236299E-33	TBK1, EEF1D, MAPK10, MAP3K7, HLA-DMB, HNRNPK, PER3, SRPK1, CCL5, CASP8, CCL2, NFKBIA, USP7, CLOCK, MAVS, TLR9, MCRS1, HLA-DRA, CD74, STAT2, DDX58, RELA, MAPK9, TLR2, TAB2, IL1B, MAPK8, IFNA8, MYD88, IKBKB, CREBBP, IKBKE, IL6, IRF7, TRAF5, JAK2, SKP1, PTPN11, FOS, IL12A, TRAF3, TBP, EIF2AK2, TBPL1, CDK2, TRAF2, PER1, IRF3, CYCS, FAS, IFNAR2, EIF2S1, SRSF2, STAT1, C1QBP, TICAM1, PPP1CA, EIF2AK1, EIF2AK4, CUL1, SRSF9, HLA-A, HLA-E, IFIH1, TAF6, PPP1CB, IFNAR1, TP53, FASLG, TNFRSF1A, HMGN1, HLA-G, HLA-DPB1, JUN, IFNA4, IFNA16, SOCS3, IFNA6, IFNA10, CSNK2A2, IFNA21, IFNA5, PPP1CC, IFNA1, TNF, CSNK2B, CDK1, TAP1, CSNK2A1, HLA-B, HCFC1, CHUK, TAF10, ARNTL, PER2, FADD, IFNA14, IFNA17, TRAF6, IKBKG, IFNG, JAK1, EP300, HLA-F, NFKBIB, IFNB1, HLA-DRB1, TAB1, NFKB1, MED8, EIF2AK3, TYK2, CASP3, PML	1481	183	6910	2.906542987126554	1.1979963515614378E-30	3.6302919744285994E-32	6.022737668745399E-30
KEGG_PATHWAY	hsa05160:Hepatitis C	93	5.002689618074233	8.482465349071222E-33	EIF3E, PPP2R2D, PPP2R2A, TBK1, STAT1, PPP2CB, LDLR, PPP2R1B, PPP2R1A, PIK3CG, MAPK12, ARAF, MAPK10, TICAM1, PPP2R2C, PIK3R1, GRB2, PIK3R3, PDPK1, EIF2AK1, EIF2AK4, MAPK11, PPP2R2B, CDKN1A, PPARA, MAPK13, BRAF, GSK3B, BAD, NFKBIA, IFNAR1, SOS1, MAVS, TP53, TNFRSF1A, STAT2, DDX58, PPP2CA, TRADD, RELA, MAPK9, EGF, SOS2, PIK3R2, MAPK14, IFNA4, IFNA16, SOCS3, PIAS1, MAPK8, IFNA8, IFNA6, IFNA10, IRF1, IFNA21, IFNA5, IFNA1, IKBKB, TNF, IKBKE, IRF7, CHUK, AKT3, RIPK1, PIK3CD, AKT2, MAPK1, IFNA14, IFNA17, TRAF6, IKBKG, TRAF3, JAK1, PIK3R5, IFNB1, EIF2AK2, MAPK3, NFKB1, TRAF2, IRF3, RAF1, PIK3CB, TYK2, EIF2AK3, PIK3CA, IFNAR2, EIF2S1, KRAS, EGFR, CXCL8, STAT3, NRAS, AKT1	1481	133	6910	3.262528366832002	2.2054409907585176E-30	6.486591149289758E-32	1.1087506663875934E-29
KEGG_PATHWAY	hsa04110:Cell cycle	89	4.787520172135556	9.228698503916217E-33	CCNB2, CCND1, CDC16, CCNE2, ANAPC1, HDAC2, GADD45B, CDC20, SFN, CDKN2A, YWHAB, SMAD3, CDKN2B, CDC6, PLK1, MDM2, ESPL1, CUL1, CDC27, CDC25A, CDKN1A, CDK6, PKMYT1, SMC3, CDC25C, MCM6, RB1, ANAPC11, CHEK1, E2F1, ZBTB17, ANAPC10, FZR1, GSK3B, CCNE1, ABL1, CCNA2, TP53, CCNB1, YWHAE, SMC1A, ORC2, CDKN1B, TGFB1, E2F3, ANAPC5, ANAPC4, MAD2L1, ANAPC2, E2F4, CCND2, ORC4, PTTG1, CREBBP, CDK1, PTTG2, TGFB2, CDK7, YWHAG, PRKDC, HDAC1, ATM, SKP1, RBX1, MAD2L2, RBL1, MYC, CDC14A, CCND3, PCNA, CDC26, YWHAZ, SMC1B, BUB3, MAD1L1, BUB1, EP300, CCNA1, CHEK2, CDK2, SMAD2, ATR, SMAD4, CDC14B, CDK4, ORC5, TFDP1, YWHAH, TFDP2	1481	124	6910	3.3488161878416935	2.3994616110182166E-30	6.85560460290919E-32	1.206291472470049E-29
KEGG_PATHWAY	hsa05221:Acute myeloid leukemia	54	2.9047875201721354	2.227773591443041E-32	CCND1, TCF7, PIK3CG, ARAF, STAT5A, PIK3R1, PIK3R3, GRB2, RUNX1T1, LEF1, MAP2K2, CEBPA, BRAF, TCF7L2, TCF7L1, BAD, RUNX1, SPI1, SOS1, RELA, SOS2, PIM2, PIK3R2, RPS6KB1, IKBKB, MAP2K1, CHUK, AKT3, RARA, PIK3CD, STAT5B, AKT2, MAPK1, MYC, MTOR, IKBKG, FLT3, PIK3R5, PPARD, EIF4EBP1, MAPK3, JUP, NFKB1, KIT, RAF1, PIK3CB, PIK3CA, ZBTB16, KRAS, NRAS, AKT1, STAT3, PML, PIM1	1481	56	6910	4.499131860711874	5.7922113377519066E-30	1.6089475938199742E-31	2.91194287559761E-29
KEGG_PATHWAY	hsa04261:Adrenergic signaling in cardiomyocytes	98	5.27165142549758	2.74317059363359E-32	PPP2R2D, PPP2R2A, ADCY9, PPP2CB, CREB3L4, PPP2R1B, PPP2R1A, PIK3CG, PRKACG, PLCB3, MAPK12, ADCY2, ADCY1, PLCB4, PPP1CA, PPP2R2C, CALML5, PIK3R1, CALM3, CREB3L1, CALML3, PPP1R1A, CREB3L3, PIK3R3, PPP2R3C, CREB3, MAPK11, CAMK2A, CREB5, FXYD2, ADCY5, PPP2R2B, PRKACA, ATP1A1, GNAI1, PRKACB, MAPK13, ATP1B1, BCL2, PLCB2, ADCY7, GNAS, PPP1CB, ATP2B4, ADCY4, SCN1B, MYH7, RYR2, CREB1, PPP2CA, CAMK2G, PIK3R2, MAPK14, CAMK2B, PPP2R5E, CAMK2D, MYL2, PPP1CC, PLCB1, PRKCA, ADRB1, GNAI2, AKT3, PPP2R5C, CALML6, PIK3CD, ATP1A2, AKT2, MAPK1, ACTC1, PPP2R5D, CREB3L2, CREM, GNAI3, PPP2R5A, KCNQ1, ADCY3, PIK3R5, ATF4, PLN, KCNE1, ATF2, CACNA1C, GNAQ, PPP2R3A, MAPK3, SLC9A1, AGTR1, PPP2R5B, ADCY8, ADCY6, ADRB2, ATF6B, PIK3CB, ATP1A3, PIK3CA, RPS6KA5, AKT1	1481	146	6910	3.131815785335714	7.132243543447335E-30	1.9276333901209013E-31	3.5856229274654427E-29
KEGG_PATHWAY	hsa05214:Glioma	59	3.1737493275954813	8.578737451180345E-32	CCND1, IGF1, PDGFRA, PIK3CG, CDKN2A, ARAF, CALML5, CALM3, PIK3R1, CALML3, GRB2, PIK3R3, MDM2, PLCG2, CAMK2A, CDK6, CDKN1A, MAP2K2, PDGFB, SHC1, BRAF, RB1, E2F1, SHC2, PRKCB, PDGFA, SOS1, TP53, IGF1R, SHC3, SHC4, CAMK2G, EGF, SOS2, PTEN, CAMK2B, PIK3R2, E2F3, CAMK2D, PRKCA, MAP2K1, AKT3, CALML6, PIK3CD, AKT2, MAPK1, MTOR, PIK3R5, PRKCG, PLCG1, MAPK3, RAF1, PIK3CB, CDK4, PIK3CA, KRAS, EGFR, NRAS, AKT1	1481	65	6910	4.235080247234197	2.2304717373068899E-29	5.869662466597079E-31	1.1213344793447206E-28
KEGG_PATHWAY	hsa04725:Cholinergic synapse	82	4.410973641742872	1.244315162429064E-31	ITPR3, ADCY9, GNG4, CREB3L4, GNG10, PRKACG, PIK3CG, PLCB3, ADCY1, ADCY2, PLCB4, PIK3R1, CREB3L1, CREB3L3, PIK3R3, CREB3, CREB5, CAMK2A, ADCY5, CHRM4, CHRM2, PRKACA, GNAI1, PRKACB, GNB4, GNA11, BCL2, ADCY7, PLCB2, ADCY4, GNG13, PRKCB, KCNQ2, CREB1, CAMK2G, CAMK2B, PIK3R2, CAMK2D, PRKCA, PLCB1, KCNJ12, MAP2K1, CACNA1A, GNG2, ITPR1, GNAI2, GNG12, AKT3, GNB3, KCNJ6, PIK3CD, JAK2, GNB2, AKT2, MAPK1, FYN, FOS, CREB3L2, GNAI3, GNB5, KCNQ1, ADCY3, PIK3R5, ATF4, PRKCG, GNG8, GNAQ, CACNA1C, MAPK3, CAMK4, GNG7, ADCY6, ADCY8, GNG3, PIK3CB, GNG5, GNAO1, PIK3CA, KRAS, GNGT1, NRAS, AKT1	1481	111	6910	3.4467823664312522	3.2352194223155666E-29	8.295434416193762E-31	1.6264555276850886E-28
KEGG_PATHWAY	hsa05145:Toxoplasmosis	85	4.57235072619688	1.8010255224811815E-31	STAT1, LDLR, IRAK4, PIK3CG, TLR4, MAPK12, MAPK10, SOCS1, MAP3K7, PIK3R1, HSPA8, PIK3R3, PDPK1, MAPK11, HLA-DMB, GNAI1, CASP9, MAPK13, BCL2, ITGB1, CASP8, BAD, NFKBIA, TNFRSF1A, HLA-DRA, BCL2L1, HLA-DPB1, LAMA5, MAPK9, RELA, PIK3R2, TLR2, MAPK14, TAB2, TGFB1, MAPK8, MYD88, HSPA1L, MAP2K6, IKBKB, TNF, BIRC3, NOS2, TGFB2, GNAI2, CHUK, AKT3, BIRC2, PIK3CD, JAK2, IRAK1, AKT2, IL10, MAPK1, IL10RB, LAMC1, IL12A, TRAF6, IKBKG, MAP2K3, HSPA6, GNAI3, IFNG, CIITA, JAK1, PIK3R5, CD40, NFKBIB, HSPA2, MAPK3, HLA-DRB1, TAB1, NFKB1, LAMA1, CYCS, CCR5, PIK3CB, TYK2, GNAO1, HSPA1A, PIK3CA, CASP3, ITGA6, STAT3, AKT1	1481	118	6910	3.360933405051557	4.682666358451072E-29	1.170666589612768E-30	2.354136640771212E-28
KEGG_PATHWAY	hsa04022:cGMP-PKG signaling pathway	105	5.6481979558902635	2.8933428183925177E-31	ADCY9, CREB3L4, ADCY1, ADCY2, PLCB4, NFATC2, CALML5, CALM3, IRS4, INS, INSR, MAP2K2, GNA11, MEF2D, ADCY7, ATP2B4, BAD, ROCK1, ADCY4, GNA13, RHOA, PLCB1, VDAC2, MAP2K1, ITPR1, ATP2A2, RGS2, AKT3, ATP1A2, NFATC1, AKT2, MAPK1, SRF, CREB3L2, GNAI3, ADCY3, PLN, MAPK3, PRKG1, AGTR1, BDKRB2, SLC25A4, ADCY6, IRS2, RAF1, ADRB2, MEF2C, PIK3CB, SLC8A1, PIK3CA, AKT1, ITPR3, PRKG2, PIK3CG, PPP3CA, PLCB3, IRS1, PPP1CA, PRKCE, PIK3R1, CALML3, CREB3L1, CREB3L3, PIK3R3, CREB3, CREB5, FXYD2, ADCY5, GNAI1, ATP1A1, PPP3R1, ATP1B1, PLCB2, PPP1CB, CREB1, PIK3R2, VDAC3, PPP1CC, ADRB1, GNAI2, PPP3CB, NPR1, SLC25A5, CALML6, PIK3CD, NOS3, NFATC3, PPP3R2, ATF4, PIK3R5, NPPB, PPP3CC, TRPC6, GNAQ, CACNA1C, ATF2, ATP2A3, ADCY8, MYLK, VASP, ATF6B, PDE3B, MYL9, ATP1A3, NFATC4	1481	166	6910	2.951237766732019	7.522691327820546E-29	1.83480276288306E-30	3.7819143915886644E-28
KEGG_PATHWAY	hsa04912:GnRH signaling pathway	72	3.8730500268961805	5.122555584571685E-31	ITPR3, ADCY9, SRC, ELK1, PTK2B, PRKACG, MAPK12, PLCB3, MAPK10, ADCY1, ADCY2, PLCB4, CALML5, CALM3, CALML3, GRB2, CAMK2A, MAPK11, ADCY5, PRKACA, MAP2K2, MMP14, PRKACB, MAPK13, GNA11, ADCY7, PLCB2, GNAS, MAP3K4, ADCY4, PRKCB, SOS1, JUN, PLD1, MAPK9, CAMK2G, MAP2K4, SOS2, CGA, CAMK2B, MAPK14, CAMK2D, MAPK8, CDC42, MAP2K6, PLCB1, PRKCA, MAP2K1, MAPK7, ITPR1, CALML6, MAPK1, MAP2K3, ADCY3, FSHB, ATF4, MAP3K1, GNAQ, CACNA1C, MAPK3, PRKCD, PLD2, ADCY6, ADCY8, RAF1, MAP3K2, MMP2, KRAS, MAP2K7, EGFR, MAP3K3, NRAS	1481	91	6910	3.691595372891794	1.3318644519886383E-28	3.171105838068186E-30	6.69573842541335E-28
KEGG_PATHWAY	hsa05203:Viral carcinogenesis	119	6.401291016675632	2.0434890232041617E-30	CCND1, CREB3L4, SNW1, CDC20, PRKACG, CDKN2A, CDKN2B, RBPJL, MDM2, CDKN1A, ACTN4, HNRNPK, PRKACB, MAPKAPK2, RB1, HDAC7, BAD, CASP8, NFKBIA, CCNE1, CCNA2, USP7, GTF2H1, BAX, HDAC5, YWHAE, RHOA, RELA, CDKN1B, GTF2B, CDC42, CREBBP, IRF7, TRAF5, ACTN2, ACTN1, SYK, MAPK1, RBL1, SRF, PMAIP1, TRAF3, CREB3L2, LYN, YWHAZ, TBP, EIF2AK2, CCNA1, TBPL1, MAPK3, CDK2, TRAF2, IRF3, GSN, PXN, PIK3CB, CDK4, PIK3CA, IL6ST, YWHAH, KRAS, STAT3, NRAS, SRC, CCNE2, HDAC2, PIK3CG, YWHAB, STAT5A, JAK3, PIK3R1, CREB3L1, CREB3L3, GRB2, PIK3R3, CREB3, CREB5, CDK6, CCR3, PRKACA, HLA-A, HLA-E, REL, CHEK1, POLB, CREB1, RAC1, TP53, HLA-G, JUN, HDAC8, TRADD, PIK3R2, VDAC3, DLG1, CCND2, HDAC3, CDK1, HLA-B, YWHAG, HDAC1, PIK3CD, NFKB2, STAT5B, CCND3, IKBKG, JAK1, MAD1L1, HLA-F, PIK3R5, EP300, ATF4, ATF2, EGR2, NFKB1, BAK1, ATF6B, CCR5, CASP3	1481	205	6910	2.7084204805586203	5.31307146033082E-28	1.2355980140304234E-29	2.6710628608479127E-27
KEGG_PATHWAY	hsa04919:Thyroid hormone signaling pathway	82	4.410973641742872	2.747277914329393E-30	CCND1, STAT1, SRC, HDAC2, PIK3CG, TSC2, PRKACG, ACTB, PLCB3, FOXO1, PLCB4, NCOA3, PIK3R1, NOTCH2, PIK3R3, PDPK1, MDM2, PLCG2, FXYD2, RHEB, PRKACA, MAP2K2, ATP1A1, PRKACB, CASP9, ATP1B1, PLCB2, TBC1D4, GSK3B, SIN3A, BAD, PRKCB, ITGB3, MED14, TP53, NOTCH4, MED13L, PIK3R2, RXRG, PLCB1, NCOR1, PRKCA, HDAC3, NCOA2, MAP2K1, CREBBP, CTNNB1, HDAC1, NOTCH1, AKT3, PIK3CD, ITGAV, ATP1A2, RXRB, AKT2, MAPK1, MYC, MTOR, NOTCH3, PLCE1, PIK3R5, EP300, THRB, PLN, THRA, HIF1A, PRKCG, PLCG1, MAPK3, SLC9A1, RAF1, ESR1, RCAN2, PIK3CB, ATP1A3, RCAN1, PIK3CA, ACTG1, KRAS, MED1, NRAS, AKT1	1481	114	6910	3.35607756731464	7.142922577256422E-28	1.623391494831005E-29	3.59099164324692E-27
KEGG_PATHWAY	hsa04917:Prolactin signaling pathway	61	3.28133405056482	5.366742943351575E-30	CCND1, STAT1, SRC, TNFRSF11A, TNFSF11, PIK3CG, MAPK12, MAPK10, STAT5A, SOCS5, SOCS1, PIK3R1, SOCS4, SOCS7, GRB2, PIK3R3, MAPK11, INS, MAP2K2, SHC1, MAPK13, SHC2, GSK3B, SOS1, CISH, FOXO3, ESR2, SHC3, SHC4, RELA, MAPK9, SOS2, CGA, MAPK14, PIK3R2, SOCS2, SOCS3, MAPK8, PRL, IRF1, CCND2, MAP2K1, AKT3, PIK3CD, JAK2, STAT5B, AKT2, MAPK1, FOS, PIK3R5, MAPK3, NFKB1, PRLR, RAF1, ESR1, PIK3CB, PIK3CA, KRAS, STAT3, NRAS, AKT1	1481	71	6910	4.008616180540366	1.3953531652714095E-27	3.100784811714243E-29	7.014917915843302E-27
KEGG_PATHWAY	hsa05213:Endometrial cancer	50	2.6896180742334588	9.400347102621893E-30	CCND1, TCF7, ELK1, AXIN1, MLH1, PIK3CG, MAP2K1, CTNNA1, ARAF, CTNNB1, AKT3, PIK3R1, CDH1, PIK3CD, GRB2, PIK3R3, PDPK1, ERBB2, AKT2, APC, MAPK1, MYC, LEF1, MAP2K2, CASP9, TCF7L2, BRAF, TCF7L1, PIK3R5, GSK3B, BAD, MAPK3, AXIN2, SOS1, FOXO3, TP53, RAF1, PIK3CB, CTNNA3, ILK, PIK3CA, EGF, SOS2, KRAS, PIK3R2, PTEN, EGFR, NRAS, AKT1, CTNNA2	1481	52	6910	4.486313821222667	2.444090246681692E-27	5.313239666699331E-29	1.228727815015233E-26
KEGG_PATHWAY	hsa04720:Long-term potentiation	58	3.1199569661108124	1.3768403163179424E-29	ITPR3, PRKACG, PPP3CA, PLCB3, ARAF, GRIA2, GRIN2A, ADCY1, PPP1CA, PLCB4, CALML5, CALM3, CALML3, PPP1R1A, GRIN2D, CAMK2A, PRKACA, MAP2K2, PRKACB, PPP3R1, BRAF, PLCB2, PPP1CB, PRKCB, GRIA1, RPS6KA1, RPS6KA6, CAMK2G, CAMK2B, CAMK2D, PPP1CC, RPS6KA2, PRKCA, PLCB1, GRIN1, MAP2K1, CREBBP, ITPR1, PPP3CB, CALML6, MAPK1, RAP1B, RAP1A, PPP3R2, EP300, ATF4, RPS6KA3, PPP3CC, PRKCG, CACNA1C, GNAQ, MAPK3, CAMK4, ADCY8, RAF1, GRIN2B, KRAS, NRAS	1481	66	6910	4.1002189347901705	3.57978482242665E-27	7.616563451971596E-29	1.7996803469335407E-26
KEGG_PATHWAY	hsa05212:Pancreatic cancer	57	3.066164604626143	5.715812287406723E-29	CCND1, TGFBR1, STAT1, PIK3CG, CDKN2A, MAPK10, ARAF, SMAD3, PIK3R1, PIK3R3, RAC2, CDK6, CASP9, BRAF, RB1, E2F1, BAD, RAC1, TP53, BCL2L1, TGFBR2, RELA, MAPK9, EGF, VEGFA, PIK3R2, TGFB1, E2F3, MAPK8, CDC42, IKBKB, MAP2K1, TGFB2, CHUK, AKT3, PIK3CD, ARHGEF6, ERBB2, AKT2, MAPK1, RAC3, IKBKG, JAK1, PIK3R5, MAPK3, NFKB1, RAF1, SMAD2, PIK3CB, SMAD4, CDK4, PIK3CA, BRCA2, KRAS, EGFR, AKT1, STAT3	1481	65	6910	4.091518204955072	1.486111194725748E-26	3.0960649890119755E-28	7.471189591481806E-26
KEGG_PATHWAY	hsa04068:FoxO signaling pathway	88	4.733727810650888	6.004827215672451E-28	CCNB2, CCND1, IGF1, TGFBR1, GADD45B, PIK3CG, ATG12, MAPK12, BCL6, ARAF, MAPK10, SMAD3, FOXO1, IRS1, CDKN2B, PIK3R1, PLK1, GRB2, PIK3R3, PDPK1, MDM2, MAPK11, IRS4, INS, CDKN1A, INSR, GABARAP, MAP2K2, MAPK13, BRAF, BCL2L11, PRMT1, SOS1, USP7, FOXO3, FASLG, IGF1R, CCNB1, TGFBR2, KLF2, MAPK9, EGF, SOS2, PIK3R2, MAPK14, PTEN, CDKN1B, TGFB1, FOXO6, MAPK8, CCND2, IKBKB, IL7R, GABARAPL2, MAP2K1, CREBBP, TGFB2, IL6, RAG1, CHUK, FBXO32, ATM, AKT3, GABARAPL1, PIK3CD, AKT2, CSNK1E, IL10, MAPK1, FOXO4, PRKAA1, PIK3R5, EP300, PCK1, MAPK3, CDK2, IRS2, RAF1, SLC2A4, SMAD2, PIK3CB, SMAD4, PIK3CA, KRAS, EGFR, STAT3, NRAS, AKT1	1481	134	6910	3.064085379987302	1.5612550760748373E-25	3.1862348491323206E-27	7.848963600715659E-25
KEGG_PATHWAY	hsa04916:Melanogenesis	73	3.9268423883808503	1.2711954473603934E-27	FZD6, FZD4, ADCY9, TCF7, CREB3L4, PRKACG, PLCB3, WNT10A, WNT5B, ADCY1, ADCY2, PLCB4, FZD2, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, FZD5, CREB3, CAMK2A, ADCY5, PRKACA, LEF1, GNAI1, MAP2K2, FZD9, PRKACB, TCF7L2, TCF7L1, ADCY7, PLCB2, GNAS, GSK3B, ADCY4, PRKCB, CREB1, CAMK2G, DVL2, DVL1, CAMK2B, CAMK2D, KITLG, PLCB1, PRKCA, MAP2K1, CREBBP, CTNNB1, GNAI2, MITF, POMC, CALML6, MAPK1, WNT1, FZD7, FZD8, CREB3L2, WNT3A, GNAI3, ADCY3, EP300, PRKCG, GNAQ, MAPK3, FZD10, DVL3, ADCY6, ADCY8, KIT, RAF1, GNAO1, KRAS, NRAS	1481	100	6910	3.4060094530722487	3.3051081631370226E-25	6.610216326274046E-27	1.6615909896101564E-24
KEGG_PATHWAY	hsa05210:Colorectal cancer	53	2.850995158687466	8.079011657088143E-26	CCND1, TGFBR1, TCF7, AXIN1, PIK3CG, MAPK10, ARAF, SMAD3, PIK3R1, PIK3R3, RAC2, APC, LEF1, CASP9, BCL2, BRAF, TCF7L2, TCF7L1, BAD, GSK3B, AXIN2, RAC1, TP53, JUN, TGFBR2, BAX, RHOA, MAPK9, PIK3R2, TGFB1, MAPK8, MLH1, MAP2K1, TGFB2, CTNNB1, AKT3, PIK3CD, AKT2, MAPK1, RAC3, MYC, FOS, PIK3R5, MAPK3, CYCS, RAF1, SMAD2, PIK3CB, SMAD4, PIK3CA, CASP3, KRAS, AKT1	1481	62	6910	3.988477706867635	2.1005430308429172E-23	4.1187118251821902E-25	1.0560148718474185E-22
KEGG_PATHWAY	hsa04071:Sphingolipid signaling pathway	79	4.249596557288865	3.2633362382692092E-25	PPP2R2D, PPP2R2A, PPP2CB, PPP2R1B, PPP2R1A, PIK3CG, PLCB3, MAPK12, MAPK10, PLCB4, PRKCE, PPP2R2C, PIK3R1, PIK3R3, MAP3K5, PDPK1, RAC2, PPP2R3C, MAPK11, PPP2R2B, GNAI1, MAP2K2, MAPK13, BCL2, PLCB2, ROCK1, PRKCB, RAC1, TP53, TNFRSF1A, GNA13, PLD1, BAX, PPP2CA, RHOA, TRADD, RELA, MAPK9, PTEN, MAPK14, PIK3R2, BID, PPP2R5E, MAPK8, PRKCA, PLCB1, TNF, MAP2K1, GNAI2, AKT3, PPP2R5C, PIK3CD, NOS3, AKT2, MAPK1, PPP2R5D, FYN, RAC3, GNAI3, PPP2R5A, GAB2, PIK3R5, PRKCG, GNAQ, PPP2R3A, MAPK3, S1PR3, NFKB1, TRAF2, PLD2, PPP2R5B, BDKRB2, RAF1, PIK3CB, PIK3CA, KRAS, NRAS, AKT1, PRKCZ	1481	120	6910	3.0716295295971188	8.484674219499944E-23	1.6316681191346046E-24	4.265536114714505E-22
KEGG_PATHWAY	hsa04650:Natural killer cell mediated cytotoxicity	79	4.249596557288865	1.6031895459161496E-24	PTK2B, PPP3CA, PIK3CG, ARAF, NFATC2, PIK3R1, PTPN6, GRB2, PIK3R3, RAC2, PLCG2, MAP2K2, PPP3R1, SHC1, BRAF, SHC2, PAK1, VAV2, IFNAR1, PRKCB, KIR2DL5A, ITGB2, SOS1, RAC1, FASLG, ICAM2, VAV1, ITGAL, SHC3, SHC4, SOS2, BID, PIK3R2, IFNA4, IFNA16, IFNA8, IFNA6, IFNA10, CD247, IFNA21, TNFRSF10B, LCK, IFNA5, IFNA1, PRKCA, TNF, MAP2K1, PPP3CB, LCP2, PIK3CD, NFATC1, ZAP70, SYK, PTPN11, MAPK1, IFNA14, FYN, RAC3, IFNA17, TNFRSF10A, IFNG, KIR2DL2, PPP3R2, PIK3R5, PPP3CC, IFNB1, PRKCG, PLCG1, KIR2DL4, MAPK3, RAF1, PIK3CB, PIK3CA, FAS, IFNAR2, CASP3, TYROBP, KRAS, NRAS	1481	122	6910	3.021274947144707	4.168292819381989E-22	7.864703432796205E-24	2.0955434584531295E-21
KEGG_PATHWAY	hsa05222:Small cell lung cancer	63	3.388918773534158	1.9172711586389342E-24	CCND1, CCNE2, PIK3CG, CDKN2B, COL4A5, ITGA3, COL4A1, PIK3R1, PIK3R3, CDK6, CKS2, CASP9, BCL2, RB1, E2F1, PIAS2, ITGB1, COL4A2, NFKBIA, PTGS2, CCNE1, TP53, TRAF4, COL4A6, BCL2L1, LAMA5, RELA, PTEN, PIK3R2, E2F3, COL4A3, FN1, RXRG, IKBKB, CKS1B, BIRC3, NOS2, TRAF5, CHUK, AKT3, BIRC2, PIK3CD, ITGAV, ITGA2, RXRB, AKT2, MYC, LAMC1, TRAF6, IKBKG, TRAF3, PIK3R5, NFKB1, CDK2, TRAF2, LAMA1, CYCS, PTK2, PIK3CB, CDK4, PIK3CA, ITGA6, AKT1	1481	85	6910	3.4581562537236366	4.984905012461229E-22	9.231305578631905E-24	2.506082356138821E-21
KEGG_PATHWAY	hsa04931:Insulin resistance	73	3.9268423883808503	2.3158303850429597E-24	CREB3L4, PIK3CG, MAPK10, PYGL, FOXO1, IRS1, PPP1CA, PRKCE, PIK3R1, SREBF1, CREB3L1, CREB3L3, PIK3R3, PDPK1, CREB3, CREB5, PPP1R3A, INS, INSR, PPARA, GYS1, TBC1D4, PPP1CB, GSK3B, NFKBIA, PPP1R3E, CREB1, TNFRSF1A, RPS6KA1, CRTC2, RPS6KA6, MAPK9, RELA, PIK3R2, PTEN, SOCS3, MAPK8, PPP1CC, RPS6KB1, IKBKB, RPS6KA2, TNF, PPP1R3B, PPP1R3C, IL6, AKT3, PTPRF, PIK3CD, PYGM, NOS3, AKT2, PTPN11, PYGB, MTOR, CREB3L2, GYS2, PRKAA1, PIK3R5, RPS6KA3, PPP1R3D, PCK1, NFKB1, PRKCD, PTPN1, IRS2, SLC2A4, PRKCQ, PIK3CB, CPT1A, PIK3CA, STAT3, AKT1, PRKCZ	1481	108	6910	3.153712456548378	6.021159001111695E-22	1.0947561820203083E-23	3.027042701610521E-21
KEGG_PATHWAY	hsa04662:B cell receptor signaling pathway	55	2.9585798816568047	5.7556678212273065E-24	PIK3CG, PPP3CA, INPPL1, BTK, NFATC2, PIK3R1, PTPN6, PIK3R3, GRB2, RAC2, PLCG2, MAP2K2, PPP3R1, GSK3B, NFKBIA, VAV2, SOS1, BLNK, RAC1, JUN, INPP5D, VAV1, RELA, SOS2, PIK3R2, BCL10, IKBKB, MAP2K1, MALT1, PPP3CB, CHUK, AKT3, PIK3CD, NFATC1, SYK, AKT2, MAPK1, RAC3, NFATC3, FOS, NFKBIE, IKBKG, LYN, PPP3R2, PIK3R5, NFKBIB, PPP3CC, MAPK3, NFKB1, RAF1, PIK3CB, PIK3CA, KRAS, NRAS, AKT1	1481	69	6910	3.719089138752704	1.4964736335190996E-21	2.672274345569821E-23	7.523285117799095E-21
KEGG_PATHWAY	hsa04064:NF-kappa B signaling pathway	63	3.388918773534158	1.5005163425258986E-23	IRAK4, MAP3K14, TNFRSF11A, TNFSF11, TLR4, TICAM1, BTK, MAP3K7, IL1R1, PLCG2, TICAM2, BCL2, CFLAR, NFKBIA, PTGS2, PIAS4, BLNK, TNFRSF1A, BCL2L1, TIRAP, RELB, CXCL12, DDX58, CCL19, TRADD, RELA, PLAU, TAB2, IL1B, CSNK2A2, MYD88, LCK, BCL10, IKBKB, CSNK2B, BIRC3, TNF, MALT1, CSNK2A1, TRAF5, CHUK, ATM, RIPK1, BIRC2, NFKB2, ZAP70, IRAK1, SYK, TRAF6, IKBKG, UBE2I, TRAF3, LYN, VCAM1, CD40, PLCG1, CCL4, TAB1, NFKB1, TRAF2, CCL13, PRKCQ, CXCL8	1481	87	6910	3.3786584088104497	3.901342490567336E-21	6.844460509767257E-23	1.9613383918900763E-20
KEGG_PATHWAY	hsa04210:Apoptosis	51	2.743410435718128	2.3329637708940516E-23	CSF2RB, MAP3K14, PIK3CG, PIK3R1, PIK3R3, CASP7, CASP9, CASP6, BCL2, CFLAR, CASP8, BAD, NFKBIA, TP53, TNFRSF1A, FASLG, BCL2L1, BAX, RELA, IL3RA, TRADD, PIK3R2, BID, NGF, TNFRSF10B, IKBKB, DFFA, BIRC3, TNF, CHUK, ATM, RIPK1, AKT3, BIRC2, PIK3CD, FADD, AKT2, NTRK1, IKBKG, TNFRSF10A, PIK3R5, NFKB1, CAPN1, TRAF2, CASP10, CYCS, PIK3CB, PIK3CA, FAS, CASP3, AKT1	1481	62	6910	3.8379691141556487	6.0657058043245344E-21	1.0458113455731955E-22	3.0494379041820874E-20
KEGG_PATHWAY	hsa04540:Gap junction	63	3.388918773534158	4.0231884979768654E-23	TUBB, TUBB4A, ITPR3, ADCY9, TUBA1A, PRKG2, SRC, PDGFD, PDGFRA, PRKACG, PLCB3, ADCY1, TUBB4B, ADCY2, CSNK1D, PLCB4, GRB2, TUBA4A, TUBA1C, ADCY5, PRKACA, GNAI1, MAP2K2, PDGFB, PRKACB, GNA11, ADCY7, PLCB2, GNAS, ADCY4, PRKCB, PDGFA, SOS1, PDGFC, SOS2, EGF, DRD2, PRKCA, PLCB1, MAP2K1, CDK1, MAPK7, ITPR1, ADRB1, MAP2K5, GNAI2, MAPK1, TJP1, GNAI3, TUBB3, ADCY3, PRKCG, GNAQ, MAPK3, PRKG1, ADCY6, ADCY8, RAF1, MAP3K2, TUBB2A, KRAS, EGFR, NRAS	1481	88	6910	3.3402645632557855	1.046029009473985E-20	1.772930524532178E-22	5.2587458298584984E-20
KEGG_PATHWAY	hsa04921:Oxytocin signaling pathway	91	4.895104895104895	5.712855730832268E-23	CCND1, ITPR3, ADCY9, SRC, ELK1, PPP3CA, PIK3CG, PRKACG, ACTB, PLCB3, ADCY1, ADCY2, PPP1CA, PLCB4, NFATC2, CALML5, PIK3R1, CALM3, CALML3, PIK3R3, CAMK2A, ADCY5, CDKN1A, PRKACA, GNAI1, MAP2K2, PRKACB, PPP3R1, ADCY7, PLCB2, GNAS, PPP1CB, PTGS2, ROCK1, ADCY4, PRKCB, RYR2, JUN, RHOA, CAMK2G, PIK3R2, CAMK2B, CAMK2D, PPP1CC, PLCB1, PRKCA, KCNJ12, MAP2K1, MAPK7, KCNJ9, MAP2K5, ITPR1, GNAI2, PPP3CB, RGS2, NPR1, CALML6, PIK3CD, KCNJ6, NFATC1, NOS3, MAPK1, NFATC3, FOS, GNAI3, PRKAA1, ADCY3, PPP3R2, PIK3R5, PPP3CC, PRKCG, GNAQ, CACNA1C, MAPK3, CAMK4, CAMKK2, ADCY6, ADCY8, RAF1, MEF2C, MYLK, PIK3CB, MYL9, GNAO1, RCAN1, PIK3CA, NFATC4, ACTG1, KRAS, EGFR, NRAS	1481	158	6910	2.6872451901298304	1.4853424900163896E-20	2.4755708166939827E-22	7.467325049821758E-20
KEGG_PATHWAY	hsa04370:VEGF signaling pathway	50	2.6896180742334588	9.004795240608695E-23	SRC, PIK3CG, PPP3CA, MAPK12, NFATC2, PIK3R1, PIK3R3, RAC2, PLCG2, MAPK11, MAP2K2, CASP9, MAPK13, PPP3R1, MAPKAPK2, SHC2, BAD, PTGS2, PRKCB, RAC1, KDR, VEGFA, MAPK14, PIK3R2, HSPB1, CDC42, PRKCA, MAP2K1, PPP3CB, AKT3, PIK3CD, NOS3, AKT2, MAPK1, RAC3, SH2D2A, PPP3R2, PIK3R5, PPP3CC, PRKCG, PLCG1, MAPK3, RAF1, PTK2, PXN, PIK3CB, PIK3CA, KRAS, NRAS, AKT1	1481	61	6910	3.824398667271782	2.3412467625582606E-20	3.8381094468168214E-22	1.1770248757693913E-19
KEGG_PATHWAY	hsa04611:Platelet activation	80	4.303388918773534	9.316270157123612E-23	ITPR3, ADCY9, SRC, PRKG2, PIK3CG, PRKACG, ACTB, MAPK12, PLCB3, BTK, ADCY1, ADCY2, PPP1CA, PLCB4, PIK3R1, PIK3R3, COL2A1, VAMP8, PLCG2, MAPK11, ADCY5, PRKACA, GNAI1, PRKACB, MAPK13, ADCY7, PLCB2, GNAS, PPP1CB, ITGB1, TLN1, ORAI1, ROCK1, ADCY4, ITGB3, COL1A2, MYL12B, GNA13, RHOA, VWF, PIK3R2, MAPK14, F2R, GP1BA, ARHGEF1, PPP1CC, PLCB1, ITPR1, ARHGEF12, GNAI2, AKT3, MYL12A, PRKCI, LCP2, PIK3CD, ITGA2, NOS3, AKT2, SYK, MAPK1, FYN, STIM1, RAP1A, LYN, RAP1B, GNAI3, ADCY3, PIK3R5, COL1A1, GNAQ, MAPK3, PRKG1, ADCY6, ADCY8, MYLK, VASP, PIK3CB, PIK3CA, ACTG1, AKT1, PRKCZ	1481	130	6910	2.8712408455825065	2.422230240852139E-20	3.906822969116353E-22	1.2177380419347852E-19
KEGG_PATHWAY	hsa04310:Wnt signaling pathway	83	4.464766003227542	1.1348649227963942E-22	FZD6, CCND1, FZD4, SFRP2, TCF7, AXIN1, PPP3CA, PRKACG, PLCB3, MAPK10, WNT10A, LRP5, WNT5B, PLCB4, NFATC2, MAP3K7, FZD2, RAC2, FZD5, APC, CAMK2A, CUL1, PRKACA, LEF1, FZD9, RUVBL1, PRKACB, PPP3R1, TCF7L2, FBXW11, TCF7L1, PLCB2, GSK3B, PRKCB, AXIN2, RAC1, TP53, JUN, RHOA, CAMK2G, MAPK9, DVL2, DVL1, CAMK2B, CAMK2D, FOSL1, MAPK8, CSNK2A2, CCND2, PSEN1, BTRC, PLCB1, PRKCA, CSNK2B, CREBBP, CSNK2A1, CTNNB1, PPP3CB, CTBP1, NFATC1, SKP1, RBX1, CSNK1E, WNT1, FZD7, RAC3, MYC, NFATC3, CCND3, FZD8, WNT3A, PPP3R2, EP300, PPARD, PPP3CC, PRKCG, CSNK1A1, MMP7, FZD10, DVL3, SMAD4, NFATC4, LRP6	1481	138	6910	2.806221804695222	2.950648799270625E-20	4.683569522651786E-22	1.4833921361649664E-19
KEGG_PATHWAY	hsa04622:RIG-I-like receptor signaling pathway	54	2.9047875201721354	2.4021037768225834E-22	TBK1, MAPK12, ATG12, MAPK10, MAP3K7, SIKE1, RNF125, MAPK11, PIN1, TMEM173, IFIH1, MAPK13, CASP8, NFKBIA, MAVS, DDX58, RELA, MAPK9, TRADD, MAPK14, IFNA4, IFNA16, IFNA8, MAPK8, IFNA6, IFNA10, IFNA21, IFNA5, IFNA1, IKBKB, TNF, IKBKE, TANK, IRF7, CHUK, RIPK1, FADD, IFNA14, ATG5, IFNA17, IL12A, ISG15, IKBKG, TRAF6, TRAF3, MAP3K1, NFKBIB, IFNB1, NFKB1, TRAF2, CASP10, IRF3, CXCL8, CYLD	1481	70	6910	3.5993054885694993	6.245469819738716E-20	9.758546593341744E-22	3.13981142708212E-19
KEGG_PATHWAY	hsa05223:Non-small cell lung cancer	47	2.5282409897794516	3.2164509292594395E-22	RASSF5, CCND1, RXRG, PRKCA, ALK, PIK3CG, CDKN2A, MAP2K1, ARAF, AKT3, PIK3R1, PIK3CD, GRB2, PIK3R3, PDPK1, PLCG2, RXRB, ERBB2, AKT2, MAPK1, CDK6, MAP2K2, CASP9, BRAF, RB1, E2F1, PIK3R5, BAD, PRKCG, PLCG1, MAPK3, PRKCB, SOS1, FOXO3, TP53, RAF1, PIK3CB, PIK3CA, CDK4, EGF, SOS2, KRAS, PIK3R2, EGFR, E2F3, NRAS, AKT1	1481	56	6910	3.9159110639529273	8.362772416074542E-20	1.2865803717037758E-21	4.2042519060922296E-19
KEGG_PATHWAY	hsa04750:Inflammatory mediator regulation of TRP channels	66	3.5502958579881656	6.372536229800346E-22	IGF1, ITPR3, ADCY9, SRC, PRKACG, PIK3CG, MAPK12, PLCB3, MAPK10, ADCY1, ADCY2, PPP1CA, PLCB4, PRKCE, CALML5, IL1R1, CALM3, PIK3R1, CALML3, PIK3R3, PLCG2, CAMK2A, MAPK11, ADCY5, PRKACA, PRKACB, MAPK13, ADCY7, PLCB2, GNAS, PPP1CB, ADCY4, PRKCB, CAMK2G, MAPK9, PIK3R2, CAMK2B, MAPK14, BDKRB1, PRKCH, CAMK2D, MAPK8, IL1B, NGF, PPP1CC, MAP2K6, PLCB1, PRKCA, ITPR1, CALML6, PIK3CD, TRPV4, NTRK1, MAP2K3, ADCY3, PIK3R5, PRKCG, GNAQ, PLCG1, PRKCD, BDKRB2, ADCY6, ADCY8, PRKCQ, PIK3CB, PIK3CA	1481	98	6910	3.142250823354325	1.6568594197480897E-19	2.5103930602243787E-21	8.329599356564245E-19
KEGG_PATHWAY	hsa05218:Melanoma	53	2.850995158687466	7.927046105989878E-21	CCND1, IGF1, FGF3, PDGFD, PDGFRA, PIK3CG, CDKN2A, FGF10, ARAF, FGF2, PIK3R1, CDH1, MDM2, PIK3R3, CDKN1A, CDK6, MAP2K2, PDGFB, BRAF, RB1, E2F1, BAD, FGF7, PDGFA, PDGFC, TP53, FGF18, IGF1R, EGF, PTEN, PIK3R2, E2F3, MET, MAP2K1, FGF1, MITF, AKT3, PIK3CD, HGF, AKT2, MAPK1, FGF13, PIK3R5, MAPK3, RAF1, PIK3CB, PIK3CA, CDK4, KRAS, EGFR, AKT1, NRAS, FGF12	1481	71	6910	3.4828960257153994	2.0610319875573684E-18	3.0761671456080126E-20	1.0361513181381649E-17
KEGG_PATHWAY	hsa04390:Hippo signaling pathway	85	4.57235072619688	1.3262484415500698E-20	FZD6, CCND1, FZD4, PPP2R2D, PPP2R2A, TGFBR1, TCF7, PPP2CB, AXIN1, PPP2R1B, PPP2R1A, ACTB, SMAD1, CTNNA1, YWHAB, WNT10A, SMAD3, STK3, WNT5B, CSNK1D, PPP1CA, PPP2R2C, FZD2, CDH1, LATS1, AJUBA, FZD5, APC, PPP2R2B, LEF1, FZD9, TCF7L2, FBXW11, TCF7L1, TEAD4, SOX2, PPP1CB, GSK3B, LLGL2, YAP1, ITGB2, AXIN2, TGFBR2, TP53BP2, YWHAE, PPP2CA, DVL2, DVL1, TGFB1, DLG1, CCND2, PPP1CC, BTRC, BBC3, CTGF, WWTR1, TGFB2, FGF1, CTNNB1, YWHAG, PRKCI, CSNK1E, WNT1, FZD7, MYC, BMPR2, CCND3, FZD8, YWHAZ, WNT3A, DLG4, TEAD3, GLI2, FZD10, TEAD1, DVL3, SMAD2, NF2, CTNNA3, SMAD4, ACTG1, YWHAH, TP73, CTNNA2, PRKCZ	1481	151	6910	2.6264247801065146	3.4482459480301815E-18	5.0709499235737963E-20	1.7335512529092213E-17
KEGG_PATHWAY	hsa04664:Fc epsilon RI signaling pathway	51	2.743410435718128	3.371830487919632E-20	PIK3CG, MAPK12, MAPK10, BTK, PIK3R1, GRB2, PDPK1, PIK3R3, RAC2, PLCG2, MAPK11, MAP2K2, MAPK13, VAV2, PRKCB, SOS1, RAC1, IL5, INPP5D, VAV1, MAPK9, MAP2K4, SOS2, MAPK14, PIK3R2, MAPK8, MAP2K6, PRKCA, TNF, MAP2K1, AKT3, LCP2, PIK3CD, SYK, AKT2, MAPK1, FYN, RAC3, MAP2K3, LYN, GAB2, PIK3R5, PLCG1, MAPK3, RAF1, PIK3CB, PIK3CA, KRAS, MAP2K7, NRAS, AKT1	1481	68	6910	3.4993247805536796	8.766759268591042E-18	1.2705448215349336E-19	4.407349923140259E-17
KEGG_PATHWAY	hsa05211:Renal cell carcinoma	49	2.63582571274879	1.4291768941672196E-19	ARNT, EPAS1, PIK3CG, ARAF, PIK3R1, PIK3R3, GRB2, MAP2K2, PAK3, PDGFB, BRAF, PAK1, SOS1, RAC1, JUN, VEGFA, SOS2, PIK3R2, TGFB1, CDC42, MET, CREBBP, MAP2K1, PAK6, TGFB2, AKT3, CRKL, PIK3CD, HGF, PTPN11, RBX1, AKT2, MAPK1, CRK, RAP1B, RAP1A, EP300, PIK3R5, PAK4, HIF1A, MAPK3, PAK2, GAB1, RAF1, PIK3CB, PIK3CA, KRAS, AKT1, NRAS	1481	65	6910	3.5172700358385707	3.715859924834771E-17	5.30837132119253E-19	1.868089958029902E-16
KEGG_PATHWAY	hsa04670:Leukocyte transendothelial migration	71	3.8192576654115116	1.7967300370545417E-19	RASSF5, PTK2B, ACTB, PIK3CG, MMP9, CTNNA1, MAPK12, CXCR4, PIK3R1, EZR, PIK3R3, RAC2, CTNND1, PLCG2, MAPK11, JAM2, ACTN4, GNAI1, MAPK13, ITGB1, MSN, ROCK1, VAV2, PRKCB, ITGB2, RAC1, MYL12B, ITK, CXCL12, VAV1, ITGAL, RHOA, PIK3R2, MAPK14, MYL7, MYL2, CDC42, PRKCA, NCF1, CTNNB1, GNAI2, ACTN2, ACTN1, TXK, MYL12A, BCAR1, PIK3CD, PTPN11, ITGAM, MYL10, RAP1A, RAP1B, GNAI3, VCAM1, PIK3R5, JAM3, PRKCG, MYLPF, PLCG1, VASP, MYL5, NCF4, PXN, PTK2, CTNNA3, MYL9, PIK3CB, MMP2, PIK3CA, ACTG1, F11R, CTNNA2	1481	118	6910	2.8073679030430654	4.671498096341808E-17	6.579574783580012E-19	2.3485219731795946E-16
KEGG_PATHWAY	hsa05146:Amoebiasis	66	3.5502958579881656	3.1192153341765884E-19	C8B, TLR4, PRKACG, PIK3CG, PLCB3, COL4A5, ADCY1, PLCB4, COL4A1, IL1R1, PIK3R1, PIK3R3, COL2A1, PRKACA, ACTN4, PRKACB, GNA11, PLCB2, GNAS, C9, COL4A2, PRKCB, ITGB2, COL1A2, COL4A6, LAMA5, RELA, TLR2, PIK3R2, HSPB1, TGFB1, IL1B, COL4A3, FN1, PRKCA, PLCB1, IL1R2, GNA15, TNF, NOS2, IL6, RAB5B, TGFB2, ACTN2, ACTN1, PIK3CD, IL10, GNAL, LAMC1, ITGAM, IL12A, IFNG, PIK3R5, PRKCG, COL1A1, GNAQ, NFKB1, LAMA1, RAB7A, RAB5C, RAB5A, PTK2, PIK3CB, PIK3CA, CASP3, CXCL8	1481	106	6910	2.9050998178181495	8.10995986885913E-17	1.1263833151193236E-18	4.0771543861990193E-16
KEGG_PATHWAY	hsa05031:Amphetamine addiction	49	2.63582571274879	4.144021417489339E-19	PPP1CC, PRKCA, CREB3L4, GRIN1, PRKACG, PPP3CA, GRIA2, GRIA3, GRIN2A, PPP3CB, PPP1CA, STX1A, CALML5, CALML6, CALM3, CREB3L1, CALML3, PPP1R1B, CREB3L3, GRIA4, GRIN2D, CREB3, CREB5, CAMK2A, ADCY5, PRKACA, FOS, PRKACB, PPP3R1, CREB3L2, PPP3R2, GNAS, ATF4, PPP1CB, PPP3CC, PRKCG, ATF2, CACNA1C, PRKCB, CAMK4, CREB1, GRIA1, JUN, ATF6B, CAMK2G, GRIN2B, CAMK2B, FOSB, CAMK2D	1481	66	6910	3.463978065598593	1.077445568547228E-16	1.47595283362634E-18	5.41668762451102E-16
KEGG_PATHWAY	hsa04060:Cytokine-cytokine receptor interaction	108	5.809575040344271	3.9691894741725046E-18	CSF2RB, TNFRSF11A, TNFSF11, CXCR4, TNFRSF12A, IL1R1, ACVR1, CXCR5, CCR10, PDGFB, IL4R, CCL5, CCL2, PDGFA, PDGFC, LIFR, IL12RB1, CXCL12, IL2RB, IL3RA, EGF, IL2RA, TGFB1, IL1B, IFNA8, IL21R, IL9R, CNTFR, IL21, IL1R2, IL6, TGFB2, TNFRSF17, IL12RB2, TNFSF13, IL10, IL12A, CD40, CRLF2, IL13RA1, IL2, OSMR, CSF1, IL6ST, FAS, IFNAR2, EGFR, PF4, IL2RG, TGFBR1, IL22RA2, PPBP, IL11, PDGFRA, NGFR, CCL11, CSF3R, CCR3, IFNAR1, FLT1, TNFRSF1A, IL5, FASLG, IFNLR1, KDR, TGFBR2, IL5RA, CCL19, VEGFA, IFNA4, IFNA16, IFNA6, IFNA10, VEGFC, PRL, KITLG, IFNA21, VEGFB, IFNA5, IFNA1, CSF1R, GHR, IL7R, MET, TNF, IL17A, IL17RA, HGF, IL15RA, IFNA14, IL10RB, IFNA17, BMPR2, IFNG, FLT3, IFNB1, CCL4, KIT, PRLR, CCL13, CCR5, EPOR, IL1A, CCR1, CCL3, TNFRSF1B, CXCL8, CCL7	1481	230	6910	2.190881601737956	1.0319892632848513E-15	1.3945800855200692E-17	5.188163220718905E-15
KEGG_PATHWAY	hsa04066:HIF-1 signaling pathway	61	3.28133405056482	8.360072258607667E-18	ARNT, IGF1, GAPDH, ENO1, TLR4, PIK3CG, RPS6, PIK3R1, PIK3R3, PLCG2, CAMK2A, CDKN1A, INS, INSR, MAP2K2, BCL2, ANGPT1, ANGPT2, TFRC, FLT1, PRKCB, IGF1R, PDHB, CAMK2G, RELA, EGF, VEGFA, PIK3R2, CAMK2B, CAMK2D, CDKN1B, RPS6KB1, PRKCA, MAP2K1, CREBBP, NOS2, IL6, AKT3, PIK3CD, NOS3, ERBB2, AKT2, RBX1, MAPK1, MTOR, IFNG, PIK3R5, EP300, PRKCG, HIF1A, PLCG1, EIF4EBP1, MAPK3, NFKB1, ANGPT4, EIF4E, PIK3CB, PIK3CA, EGFR, STAT3, AKT1	1481	98	6910	2.9042015185547547	2.1736187872379935E-15	2.898158382983991E-17	1.0927525555756745E-14
KEGG_PATHWAY	hsa04666:Fc gamma R-mediated phagocytosis	55	2.9585798816568047	1.6422417322671824E-17	PIK3CG, WASF2, CFL1, INPPL1, PRKCE, PIK3R1, PIK3R3, RAC2, LIMK1, PLCG2, WASL, PAK1, PTPRC, VAV2, ARPC5, PRKCB, RAC1, PLD1, INPP5D, VAV1, PIK3R2, LIMK2, CDC42, RPS6KB1, PRKCA, MAP2K1, NCF1, AKT3, CRKL, PIK3CD, SYK, AKT2, MAPK1, MARCKS, HCK, CRK, LYN, WASF3, GAB2, PIK3R5, ASAP1, ARPC1B, PRKCG, PLCG1, MAPK3, PRKCD, PLD2, RAF1, WASF1, VASP, GSN, PIK3CB, PIK3CA, ARF6, AKT1	1481	84	6910	3.0549660782611494	4.2698285038946746E-15	5.618195399861414E-17	2.146588922075732E-14
KEGG_PATHWAY	hsa04550:Signaling pathways regulating pluripotency of stem cells	76	4.088219472834857	2.774634082105712E-17	FZD6, FZD4, IGF1, AXIN1, PIK3CG, MAPK12, SMAD1, WNT10A, SMAD5, SMAD3, WNT5B, JAK3, FZD2, FGF2, PIK3R1, GRB2, PIK3R3, ACVR1, FZD5, APC, MAPK11, MAP2K2, FZD9, MAPK13, INHBA, SOX2, TCF3, GSK3B, FGFR4, AXIN2, KLF4, IGF1R, LIFR, DVL2, DVL1, PIK3R2, MAPK14, ESRRB, ID3, MAP2K1, SKIL, CTNNB1, INHBB, MEIS1, AKT3, PIK3CD, JAK2, AKT2, MAPK1, WNT1, FGFR2, FZD7, MYC, BMPR2, FZD8, SMAD9, WNT3A, JAK1, PIK3R5, PAX6, FGFR3, MAPK3, FZD10, DVL3, RAF1, SETDB1, SMAD2, PIK3CB, SMAD4, PIK3CA, IL6ST, DLX5, KRAS, STAT3, NRAS, AKT1	1481	140	6910	2.5328446030674256	7.214048613474852E-15	9.368894303214092E-17	3.626749135913984E-14
KEGG_PATHWAY	hsa04152:AMPK signaling pathway	69	3.7116729424421733	5.628293965754769E-17	CCND1, PPP2R2D, PPP2R2A, IGF1, PPP2CB, CREB3L4, PPP2R1B, PPP2R1A, TSC2, PIK3CG, IRS1, FOXO1, PFKL, PPP2R2C, MAP3K7, PIK3R1, CREB3L1, SREBF1, CREB3L3, PIK3R3, PDPK1, PPP2R3C, CREB3, CREB5, RHEB, IRS4, PPP2R2B, INS, INSR, GYS1, CCNA2, CREB1, FOXO3, TSC1, IGF1R, CRTC2, PPP2CA, PIK3R2, PPP2R5E, PFKP, RPS6KB1, AKT1S1, CFTR, AKT3, PPP2R5C, PIK3CD, AKT2, PPP2R5D, RAB11B, MTOR, PPARG, CREB3L2, GYS2, PRKAA1, PPP2R5A, PIK3R5, CCNA1, PCK1, FASN, EIF4EBP1, PPP2R3A, PPP2R5B, CAMKK2, IRS2, SLC2A4, PIK3CB, CPT1A, PIK3CA, AKT1	1481	122	6910	2.6388350804175293	2.886579864025407E-14	3.3306690738754696E-16	1.4432899320127035E-13
KEGG_PATHWAY	hsa04923:Regulation of lipolysis in adipocytes	42	2.2592791823561056	1.1186475098319005E-16	ADCY9, PRKG2, PRKACG, PIK3CG, ADRB1, IRS1, ADCY1, GNAI2, ADCY2, AKT3, NPR1, PIK3R1, PIK3CD, PIK3R3, NPY, AKT2, IRS4, ADCY5, INS, PRKACA, INSR, GNAI1, PRKACB, GNAI3, ADCY7, ADCY3, GNAS, PIK3R5, PTGS2, ADCY4, PRKG1, ADCY6, ADCY8, IRS2, ADRB2, TSHR, PDE3B, PIK3CB, PIK3CA, CGA, PIK3R2, AKT1	1481	56	6910	3.49932478055368	2.886579864025407E-14	3.3306690738754696E-16	1.4432899320127035E-13
KEGG_PATHWAY	hsa05133:Pertussis	50	2.6896180742334588	1.9576641184717858E-16	ITGA5, IRAK4, TLR4, MAPK12, MAPK10, TICAM1, CFL1, CALML5, CALM3, CALML3, MAPK11, TICAM2, CXCL5, GNAI1, CASP7, MAPK13, ITGB1, NLRP3, ITGB2, NOD1, TIRAP, JUN, RHOA, RELA, MAPK9, MAPK14, MAPK8, IL1B, CASP1, IRF1, MYD88, TNF, NOS2, IL6, GNAI2, CALML6, IRAK1, IL10, MAPK1, ITGAM, FOS, TRAF6, IL12A, GNAI3, MAPK3, NFKB1, IRF3, IL1A, CASP3, CXCL8	1481	75	6910	3.110510916047716	5.773159728050814E-14	6.661338147750939E-16	2.886579864025407E-13
KEGG_PATHWAY	hsa05100:Bacterial invasion of epithelial cells	51	2.743410435718128	3.0946413819943647E-16	ITGA5, SRC, CAV2, ACTB, PIK3CG, CTNNA1, WASF2, CAV1, PIK3R1, CDH1, PIK3R3, SHC1, WASL, SHC2, ITGB1, CBLB, ARPC5, RAC1, SHC3, SHC4, RHOA, ILK, PIK3R2, CAV3, FN1, CDC42, CBL, MET, CTNNB1, CRKL, BCAR1, PIK3CD, RHOG, MAD2L2, CLTC, ARHGAP10, CRK, PIK3R5, ARPC1B, ELMO1, GAB1, WASF1, CBLC, CTNNA3, PTK2, PXN, PIK3CB, PIK3CA, DOCK1, ACTG1, CTNNA2	1481	78	6910	3.050693398431413	8.659739592076221E-14	1.1102230246251565E-15	4.3298697960381105E-13
KEGG_PATHWAY	hsa04723:Retrograde endocannabinoid signaling	60	3.2275416890801503	4.621374446140841E-16	ITPR3, ADCY9, GNG4, GNG10, PRKACG, PLCB3, MAPK12, MAPK10, GRIA2, GRIA3, ADCY1, ADCY2, PLCB4, MAPK11, ADCY5, PRKACA, GNAI1, PRKACB, GNB4, MAPK13, ADCY7, PLCB2, PTGS2, ADCY4, GNG13, PRKCB, GRIA1, MAPK9, MAPK14, MAPK8, PRKCA, PLCB1, CACNA1A, KCNJ9, ITPR1, GNG2, GNAI2, GNG12, GNB3, KCNJ6, GRIA4, GNB2, MAPK1, GNAI3, GNB5, ADCY3, GABRG2, PRKCG, GNG8, CACNA1C, GNAQ, MAPK3, GNG7, ADCY6, ADCY8, GNG3, GNG5, GNAO1, CNR1, GNGT1	1481	101	6910	2.7717424004385585	1.1546319456101628E-13	1.4432899320127035E-15	5.773159728050814E-13
KEGG_PATHWAY	hsa04520:Adherens junction	48	2.5820333512641205	4.850199765574877E-16	CSNK2A2, TGFBR1, TCF7, SRC, CDC42, MET, ACTB, CSNK2B, CREBBP, WASF2, CTNNA1, CSNK2A1, SMAD3, CTNNB1, ACTN2, ACTN1, MAP3K7, PTPRF, CDH1, PTPN6, RAC2, CTNND1, ERBB2, MAPK1, RAC3, FYN, INSR, ACTN4, LEF1, TJP1, WASL, TCF7L2, TCF7L1, WASF3, EP300, MAPK3, PTPN1, RAC1, IGF1R, WASF1, SMAD2, TGFBR2, CTNNA3, SMAD4, RHOA, ACTG1, EGFR, CTNNA2	1481	71	6910	3.154320928949796	1.1546319456101628E-13	1.4432899320127035E-15	5.773159728050814E-13
KEGG_PATHWAY	hsa04925:Aldosterone synthesis and secretion	52	2.797202797202797	5.783644447556626E-16	ITPR3, ADCY9, LDLR, CREB3L4, PRKACG, PLCB3, ADCY2, ADCY1, PLCB4, PRKCE, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, CREB3, CAMK2A, CREB5, ADCY5, PRKACA, PRKACB, GNA11, ADCY7, PLCB2, GNAS, ORAI1, ADCY4, PRKCB, CREB1, CAMK2G, PRKD2, CAMK2B, CAMK2D, PRKCA, PLCB1, ITPR1, NPR1, CALML6, NR4A1, CREB3L2, ATF1, ADCY3, ATF4, PRKCG, ATF2, CACNA1C, GNAQ, AGTR1, CAMK4, ADCY6, ADCY8, ATF6B	1481	81	6910	2.995306808045948	1.4432899320127035E-13	1.6653345369377348E-15	7.216449660063518E-13
KEGG_PATHWAY	hsa04730:Long-term depression	43	2.3130715438407745	7.7039058363384E-16	IGF1, ITPR3, PPP2CB, PRKG2, PRKCA, PLCB1, PPP1R17, PPP2R1B, PPP2R1A, PLCB3, MAP2K1, CACNA1A, ARAF, ITPR1, GRIA2, GRIA3, GNAI2, PLCB4, CRHR1, NOS1, MAPK1, MAP2K2, GNAI1, GNA11, BRAF, LYN, GNAI3, PLCB2, GNAS, PRKCG, GNAQ, MAPK3, PRKCB, PRKG1, GRIA1, IGF1R, RAF1, GNA13, GNAO1, PPP2CA, CRH, KRAS, NRAS	1481	60	6910	3.3437992347512937	2.020605904817785E-13	2.3314683517128287E-15	1.0103029524088925E-12
KEGG_PATHWAY	hsa05131:Shigellosis	44	2.366863905325444	3.4787378073414904E-15	ITGA5, SRC, CDC42, BTRC, IKBKB, ACTB, MAPK12, WASF2, MAPK10, CHUK, PFN1, CRKL, RHOG, MAPK11, MAPK1, ATG5, MAD2L2, CRK, IKBKG, MAPK13, WASL, FBXW11, ITGB1, NFKBIB, NFKBIA, ARPC1B, ROCK1, RIPK2, MAPK3, ARPC5, NFKB1, ABL1, RAC1, NOD1, ELMO1, WASF1, DOCK1, RELA, ACTG1, MAPK9, MAPK14, CD44, CXCL8, MAPK8	1481	64	6910	3.2077143821742067	8.948397578478762E-13	1.0436096431476471E-14	4.496403249731884E-12
KEGG_PATHWAY	hsa05219:Bladder cancer	33	1.7751479289940828	1.3291518814114022E-14	CCND1, SRC, MMP9, MAP2K1, CDKN2A, ARAF, CDH1, MDM2, ERBB2, DAPK1, MAPK1, CDKN1A, MYC, MAP2K2, THBS1, BRAF, RB1, E2F1, FGFR3, MAPK3, TP53, RAF1, MMP2, CDK4, VEGFA, EGF, KRAS, RPS6KA5, EGFR, CXCL8, E2F3, NRAS, MMP1	1481	41	6910	3.755372935228339	3.4638958368304884E-12	3.985700658404312E-14	1.7419399256368706E-11
KEGG_PATHWAY	hsa04922:Glucagon signaling pathway	57	3.066164604626143	1.7007506487658917E-14	PHKB, ITPR3, CREB3L4, PRKACG, PPP3CA, PLCB3, FOXO1, PYGL, ADCY2, PLCB4, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, CREB3, CREB5, CAMK2A, PRKACA, PPARA, PRKACB, PPP3R1, GYS1, PLCB2, GNAS, PRMT1, CREB1, PDHB, CRTC2, CAMK2G, CAMK2B, CAMK2D, PLCB1, CREBBP, ITPR1, PPP3CB, AKT3, CALML6, PYGM, AKT2, PYGB, CREB3L2, GYS2, PRKAA1, PPP3R2, EP300, ATF4, PPP3CC, ATF2, GNAQ, PCK1, PHKG1, PDE3B, CPT1A, PHKG2, AKT1, PHKA2	1481	99	6910	2.6863503365866634	4.416467191958873E-12	5.0182080713057076E-14	2.220446049250313E-11
KEGG_PATHWAY	hsa04918:Thyroid hormone synthesis	45	2.4206562668101133	6.28737633083118E-14	ITPR3, ADCY9, PRKCA, CREB3L4, PLCB1, PRKACG, PLCB3, ITPR1, ADCY2, ADCY1, PLCB4, PDIA4, CREB3L1, CREB3L3, ATP1A2, HSP90B1, CREB3, PAX8, CREB5, FXYD2, ADCY5, HSPA5, PRKACA, ATP1A1, PRKACB, CREB3L2, ATP1B1, PLCB2, ADCY7, ADCY3, GNAS, ATF4, PRKCG, ATF2, ADCY4, GNAQ, PRKCB, TG, CREB1, ADCY6, ADCY8, TSHR, ATF6B, ATP1A3, CGA	1481	70	6910	2.999421240474583	1.6338042030383804E-11	1.8351986597053838E-13	8.213429936176908E-11
KEGG_PATHWAY	hsa05140:Leishmaniasis	45	2.4206562668101133	1.3154887700735998E-13	MYD88, STAT1, IRAK4, ELK1, TLR4, TNF, MAPK12, NCF1, NOS2, TGFB2, MAP3K7, PTPN6, JAK2, IRAK1, MAPK11, IL10, MAPK1, HLA-DMB, ITGAM, FOS, IL12A, TRAF6, MAPK13, IFNG, JAK1, ITGB1, NFKBIB, NFKBIA, PTGS2, MAPK3, NFKB1, HLA-DRB1, TAB1, ITGB2, HLA-DRA, JUN, HLA-DPB1, NCF4, RELA, IL1A, TLR2, MAPK14, TAB2, TGFB1, IL1B	1481	71	6910	2.957175870890434	3.420597138870107E-11	3.800293413291911E-13	1.719624442841905E-10
KEGG_PATHWAY	hsa04724:Glutamatergic synapse	61	3.28133405056482	1.5721661706053692E-13	ITPR3, ADCY9, GNG4, GNG10, PRKACG, PPP3CA, PLCB3, GRIA2, GRIA3, GRIN2A, ADCY2, ADCY1, PLCB4, GRIN2D, ADCY5, PRKACA, GNAI1, PRKACB, PPP3R1, GNB4, ADCY7, PLCB2, GNAS, ADCY4, GNG13, PRKCB, GRIA1, PLD1, PLCB1, PRKCA, GRIN1, CACNA1A, ITPR1, GNG2, GNAI2, PPP3CB, GNG12, GNB3, GRIA4, GNB2, MAPK1, GNAI3, GNB5, DLG4, ADCY3, PPP3R2, PPP3CC, PRKCG, CACNA1C, GNAQ, GNG8, MAPK3, PLD2, GNG7, ADCY6, ADCY8, GNG3, GNG5, GNAO1, GRIN2B, GNGT1	1481	114	6910	2.496594287880403	4.087397087459976E-11	4.4919623576333834E-13	2.0549117962787022E-10
KEGG_PATHWAY	hsa05014:Amyotrophic lateral sclerosis (ALS)	36	1.9365250134480902	2.0090573564558349E-13	CASP1, MAP2K6, GRIN1, TNF, PPP3CA, MAPK12, GRIA2, GRIN2A, TOMM40, PPP3CB, MAP3K5, GRIN2D, MAPK11, NOS1, MAP2K3, CASP9, MAPK13, PPP3R1, BCL2, PPP3R2, BAD, PPP3CC, NEFL, RAC1, TP53, TNFRSF1A, GRIA1, CYCS, BCL2L1, RAB5A, BAX, CASP3, GRIN2B, BID, MAPK14, TNFRSF1B	1481	50	6910	3.359351789331533	5.224709553885987E-11	5.678790770957676E-13	2.626676653960658E-10
KEGG_PATHWAY	hsa05231:Choline metabolism in cancer	56	3.012372243141474	2.557257714797529E-13	PDGFD, PDGFRA, TSC2, PIK3CG, WASF2, MAPK10, PIK3R1, GRB2, PIK3R3, PDPK1, RAC2, RHEB, MAP2K2, PDGFB, WASL, PRKCB, PDGFA, SOS1, PDGFC, RAC1, TSC1, JUN, PLD1, MAPK9, EGF, SOS2, PIK3R2, MAPK8, RPS6KB1, PRKCA, MAP2K1, AKT3, PIK3CD, AKT2, MAPK1, RAC3, MTOR, FOS, WASF3, PIK3R5, SLC22A1, PRKCG, HIF1A, PLCG1, EIF4EBP1, MAPK3, PLD2, RAF1, WASF1, PIK3CB, PIK3CA, KRAS, SP1, EGFR, NRAS, AKT1	1481	101	6910	2.5869595737426545	6.647793426850512E-11	7.147615832536758E-13	3.3421043710291087E-10
KEGG_PATHWAY	hsa04621:NOD-like receptor signaling pathway	38	2.0441097364174285	2.854770308303765E-13	CASP1, IKBKB, BIRC3, TNF, MAPK12, MAPK10, IL6, CHUK, MAP3K7, HSP90AA1, BIRC2, HSP90B1, MAPK11, MAPK1, IKBKG, TRAF6, MAPK13, NLRP1, CCL5, CASP8, NFKBIB, CCL2, NFKBIA, SUGT1, RIPK2, MAPK3, NFKB1, TAB1, NLRP3, NOD1, HSP90AB1, MAPK9, RELA, MAPK14, TAB2, CXCL8, IL1B, MAPK8	1481	55	6910	3.2236204039039964	7.421396830409321E-11	7.894795928109488E-13	3.731015496555301E-10
KEGG_PATHWAY	hsa04150:mTOR signaling pathway	39	2.097902097902098	4.860048372175229E-13	IGF1, DDIT4, RPS6KB1, PRKCA, RPS6KA2, IKBKB, TSC2, PIK3CG, TNF, RPS6, IRS1, AKT1S1, AKT3, PIK3R1, PIK3CD, PIK3R3, PDPK1, AKT2, MAPK1, RHEB, INS, MTOR, BRAF, PRKAA1, PIK3R5, RPS6KA3, PRKCG, EIF4EBP1, MAPK3, PRKCB, TSC1, EIF4E, RPS6KA1, PIK3CB, RPS6KA6, PIK3CA, PTEN, PIK3R2, AKT1	1481	58	6910	3.1373256653239894	1.2637446644703232E-10	1.3302692281058626E-12	6.353251258417458E-10
KEGG_PATHWAY	hsa04020:Calcium signaling pathway	81	4.357181280258203	1.457962791592735E-12	PHKB, ITPR3, ADCY9, PTK2B, PDGFRA, PPP3CA, PRKACG, PLCB3, GRIN2A, ADCY1, ADCY2, PLCB4, CALML5, CALM3, CALML3, GRIN2D, PLCG2, CAMK2A, CHRM2, PRKACA, PRKACB, PPP3R1, GNA11, ADCY7, PLCB2, GNAS, ATP2B4, ORAI1, HTR7, ADCY4, PRKCB, RYR2, CAMK2G, CAMK2B, BDKRB1, F2R, CAMK2D, VDAC3, PLCB1, PRKCA, GRIN1, GNA15, VDAC2, NOS2, CACNA1A, ADRB1, ERBB4, ITPR1, ATP2A2, ADORA2A, PPP3CB, SLC25A5, CALML6, NOS3, ERBB2, NOS1, GNAL, STIM1, ADCY3, PLCE1, PPP3R2, PLN, PPP3CC, PRKCG, GNAQ, CACNA1C, PLCG1, AGTR1, CAMK4, ATP2A3, BDKRB2, SLC25A4, ADCY8, ADRB2, PHKG1, MYLK, SLC8A1, PHKG2, ERBB3, EGFR, PHKA2	1481	179	6910	2.11132444860222	3.7906566774381645E-10	3.948619209381832E-12	1.905697821769081E-9
KEGG_PATHWAY	hsa04971:Gastric acid secretion	44	2.366863905325444	3.006009530218516E-12	ITPR3, ADCY9, PRKCA, PLCB1, PRKACG, PLCB3, ITPR1, ADCY1, ADCY2, GNAI2, PLCB4, CFTR, CALML5, CALM3, CALML6, EZR, CALML3, ATP1A2, CAMK2A, ADCY5, PRKACA, ATP1A1, GNAI1, PRKACB, ATP1B1, GNAI3, KCNQ1, PLCB2, ADCY7, KCNE2, ADCY3, GNAS, PRKCG, ADCY4, GNAQ, SLC9A1, PRKCB, ADCY6, ADCY8, MYLK, ATP1A3, CAMK2G, CAMK2B, CAMK2D	1481	73	6910	2.812242746015743	7.815703639835192E-10	8.057443601217074E-12	3.92922361314163E-9
KEGG_PATHWAY	hsa04911:Insulin secretion	48	2.5820333512641205	6.874008205563167E-12	ITPR3, ADCY9, PRKCA, CREB3L4, PLCB1, PRKACG, PLCB3, ADCY1, ADCY2, PLCB4, STX1A, ADCYAP1R1, CREB3L1, CREB3L3, ATP1A2, CREB3, CREB5, CAMK2A, FXYD2, ADCY5, INS, PRKACA, ATP1A1, PRKACB, CREB3L2, ATP1B1, GNA11, VAMP2, PLCB2, ADCY7, ADCY3, GNAS, ATF4, PRKCG, ATF2, ADCY4, CACNA1C, GNAQ, PRKCB, RYR2, CREB1, ADCY6, ADCY8, ATF6B, ATP1A3, CAMK2G, CAMK2B, CAMK2D	1481	85	6910	2.634785717122771	1.787254788609971E-9	1.823730055861006E-11	8.985145960593854E-9
KEGG_PATHWAY	hsa04530:Tight junction	65	3.4965034965034967	2.5339232408354814E-11	PPP2R2D, PPP2R2A, PPP2CB, SRC, RRAS2, PPP2R1B, PPP2R1A, ACTB, CTNNA1, EPB41, PRKCE, PPP2R2C, MRAS, JAM2, PPP2R2B, ACTN4, GNAI1, IGSF5, LLGL2, PRKCB, MYH7, MYH9, MYL12B, MYH10, PPP2CA, RHOA, PTEN, MYL7, PRKCH, CSNK2A2, MYL2, CDC42, MAGI1, PRKCA, CSNK2B, MAGI3, CSNK2A1, CTNNB1, GNAI2, ACTN2, ACTN1, AKT3, MYL12A, PRKCI, AKT2, TJP1, MYL10, GNAI3, JAM3, PRKCG, MYLPF, PRKCD, MPDZ, PRKCQ, MYL5, CTNNA3, MYL9, CDK4, ACTG1, RRAS, KRAS, NRAS, AKT1, F11R, PRKCZ, CTNNA2	1481	137	6910	2.2136847760193596	6.588214418457028E-9	6.654765627445158E-11	3.312120577803057E-8
KEGG_PATHWAY	hsa04144:Endocytosis	102	5.486820871436256	3.2428215590980166E-11	TSG101, VPS4B, LDLR, SMURF2, CAV2, CYTH2, CHMP4B, RAB11FIP5, CXCR4, SMAD3, GRK4, HSPA8, MDM2, ITCH, WASL, ARPC5, SNX5, USP8, IL2RB, RHOA, IL2RA, EGF, CAV3, ARRB1, TGFB1, HSPA1L, CHMP2A, CDC42, CBL, TGFB2, ERBB4, RAB5B, CAPZA1, PRKCI, STAM2, FGFR2, CLTC, RAB11B, HSPA6, RET, IST1, LDLRAP1, ASAP1, FGFR3, ARPC1B, STAM, KIF5A, GRK5, PLD2, IQSEC1, SMAD2, ADRB2, EGFR, IL2RG, TGFBR1, SRC, PDGFRA, CAV1, GIT1, HLA-A, HLA-E, TFRC, CBLB, PDCD6IP, FGFR4, SNX4, FLT1, IGF1R, HLA-G, PLD1, KDR, TGFBR2, ARRB2, NEDD4L, F2R, CSF1R, GRK1, MET, CHMP6, ADRB1, HLA-B, SMURF1, GRK7, RNF41, NTRK1, TRAF6, GRK6, HLA-F, ZFYVE27, HSPA2, RAB7A, RAB5C, KIT, RAB5A, CBLC, CCR5, HSPA1A, ARF6, ERBB3, SNF8, PML, PRKCZ	1481	258	6910	1.8446053106794589	8.43132452743589E-9	8.431322306989841E-11	4.238714934601262E-8
KEGG_PATHWAY	hsa05032:Morphine addiction	49	2.63582571274879	3.958439658644042E-11	ADCY9, GNG4, PDE4A, PRKCA, GNG10, PRKACG, CACNA1A, KCNJ9, GNG2, ADCY1, ADCY2, GNAI2, GRK4, GNG12, GNB3, KCNJ6, GNB2, ADCY5, PRKACA, OPRM1, GNAI1, PRKACB, GNB4, GNAI3, GNB5, GRK6, ADCY7, ADCY3, GABRG2, GNAS, PRKCG, ADCY4, GNG8, GNG13, PRKCB, GRK5, GNG7, ADCY6, ADCY8, GNG3, GABBR2, ARRB2, PDE3B, GNG5, GNAO1, PDE4B, GABBR1, GNGT1, ARRB1	1481	91	6910	2.5123357398846933	1.0291956176189387E-8	1.019005990698929E-10	5.1741189110998675E-8
KEGG_PATHWAY	hsa05030:Cocaine addiction	33	1.7751479289940828	3.967067321196506E-11	CREB3L4, GRIN1, PRKACG, GRIA2, GNAI2, GRIN2A, CREB3L1, PPP1R1B, CREB3L3, GRIN2D, CREB3, CREB5, ADCY5, CDK5, PRKACA, CDK5R1, GNAI1, PRKACB, CREB3L2, GNAI3, DLG4, GNAS, ATF4, ATF2, NFKB1, CREB1, JUN, ATF6B, RELA, DRD2, GRIN2B, FOSB, BDNF	1481	49	6910	3.142250823354325	1.0314384901732865E-8	1.0112144455121097E-10	5.1853943361379606E-8
KEGG_PATHWAY	hsa05216:Thyroid cancer	24	1.2910166756320602	4.326614224553734E-11	TCF7L1, CCND1, TCF7, RXRG, MAP2K1, MAPK3, CTNNB1, TP53, TFG, CDH1, RXRB, PAX8, MAPK1, NTRK1, MYC, LEF1, PPARG, KRAS, MAP2K2, CCDC6, RET, NRAS, TCF7L2, BRAF	1481	29	6910	3.861323895783371	1.124920367967519E-8	1.0921552551224067E-10	5.655359514022962E-8
KEGG_PATHWAY	hsa04115:p53 signaling pathway	40	2.151694459386767	5.199956942068782E-11	CCNB2, CCND1, MDM4, IGF1, CCND2, CCNE2, GADD45B, BBC3, SFN, TSC2, CDKN2A, CDK1, RRM2, IGFBP3, ATM, MDM2, CDKN1A, CDK6, PMAIP1, CCND3, THBS1, CASP9, CHEK1, CASP8, CCNE1, CHEK2, SESN2, CDK2, TP53, CYCS, CCNB1, ATR, BAX, CDK4, FAS, CCNG1, CASP3, TP73, PTEN, BID	1481	67	6910	2.78553216362482	1.3519873998113496E-8	1.2999878951092114E-10	6.796903040395819E-8
KEGG_PATHWAY	hsa05202:Transcriptional misregulation in cancer	74	3.9806347498655192	7.2982299860115E-11	LDB1, IGF1, HDAC2, NGFR, MMP9, SMAD1, BCL6, FOXO1, GRIA3, MDM2, RUNX1T1, ITGB7, CDKN1A, CEBPA, ELK4, REL, ZBTB17, TCF3, ETV6, SIN3A, RUNX1, FLT1, SPI1, EWSR1, PDGFA, TP53, IGF1R, BCL2L1, TGFBR2, IL2RB, FUS, DDIT3, RELA, MEN1, PLAU, AFF1, CDKN1B, MLLT1, CSF1R, CCND2, RXRG, MET, NCOR1, IL1R2, CCNT1, CDK9, IL6, IGFBP3, MEIS1, ATM, HDAC1, RARA, RXRB, PAX8, NTRK1, MYC, PPARG, ITGAM, FLT3, ATF1, CD40, JMJD1C, JUP, NFKB1, MEF2C, TFE3, CEBPE, PTK2, MMP3, CEBPB, ZBTB16, SP1, CXCL8, PML	1481	168	6910	2.055158998102955	1.8975394366904652E-8	1.8071799612329187E-10	9.539580236861411E-8
KEGG_PATHWAY	hsa04270:Vascular smooth muscle contraction	58	3.1199569661108124	9.231652520817918E-11	ITPR3, ADCY9, PRKACG, PLCB3, ARAF, ADCY1, ADCY2, PPP1R14A, PLCB4, PPP1CA, PRKCE, CALML5, CALM3, CALML3, ADCY5, PRKACA, MAP2K2, PRKACB, GNA11, BRAF, ADCY7, PLCB2, GNAS, PPP1CB, ROCK1, ADCY4, PRKCB, GNA13, RHOA, PRKCH, PLA2G2A, ARHGEF1, PPP1CC, PRKCA, PLCB1, MAP2K1, ITPR1, ADORA2A, ARHGEF12, NPR1, CALML6, MAPK1, ADCY3, PRKCG, CACNA1C, GNAQ, MAPK3, PLA2G10, PRKCD, PRKG1, AGTR1, ADCY6, ADCY8, RAF1, PRKCQ, MYLK, MYL9, ACTG2	1481	119	6910	2.2740710058500104	2.4002286491686675E-8	2.2643664721044843E-10	1.2066770915808434E-7
KEGG_PATHWAY	hsa04960:Aldosterone-regulated sodium reabsorption	28	1.506186121570737	1.8081909381709593E-10	IGF1, PRKCA, SFN, PIK3CG, IRS1, PIK3R1, PIK3CD, ATP1A2, PDPK1, PIK3R3, MAPK1, FXYD2, INS, INSR, ATP1A1, ATP1B1, PIK3R5, PRKCG, MAPK3, PRKCB, PIK3CB, NEDD4L, ATP1A3, NR3C2, PIK3CA, PIK3R2, KRAS, SCNN1G	1481	39	6910	3.3497809865129247	4.701297462439413E-8	4.3937364857526973E-10	2.3635031709545729E-7
KEGG_PATHWAY	hsa05120:Epithelial cell signaling in Helicobacter pylori infection	39	2.097902097902098	2.657105378665636E-10	SRC, CDC42, MAP3K14, IKBKB, MET, CSK, MAPK12, MAPK10, CHUK, ATP6V0A1, PLCG2, PTPN11, MAPK11, JAM2, GIT1, IKBKG, MAPK13, LYN, TJP1, CCL5, IGSF5, PAK1, NFKBIA, JAM3, PLCG1, NFKB1, RAC1, ADAM17, NOD1, JUN, RELA, MAPK9, MAP2K4, CASP3, MAPK14, EGFR, CXCL8, F11R, MAPK8	1481	67	6910	2.7158938595341997	6.908474448064084E-8	6.396735363622952E-10	3.473126675146432E-7
KEGG_PATHWAY	hsa04726:Serotonergic synapse	54	2.9047875201721354	4.916876790504074E-10	ITPR3, GNG4, GNG10, PRKACG, PLCB3, ARAF, HTR1E, PLCB4, ADCY5, PRKACA, GNAI1, PRKACB, GNB4, BRAF, PLCB2, GNAS, PTGS2, HTR7, GNG13, PRKCB, PRKCA, PLCB1, MAP2K1, KCNJ9, CACNA1A, ITPR1, GNG2, GNAI2, GNG12, GNB3, KCNJ6, GNB2, MAPK1, HTR1F, GNAI3, HTR1D, GNB5, HTR1B, PRKCG, GNG8, CACNA1C, GNAQ, MAPK3, APP, GNG7, GNG3, RAF1, HTR1A, GNG5, GNAO1, CASP3, KRAS, GNGT1, NRAS	1481	111	6910	2.2698322900888734	1.278387914416257E-7	1.17283305289817E-9	6.426893905953079E-7
KEGG_PATHWAY	hsa04930:Type II diabetes mellitus	31	1.6675632060247445	8.048715645985729E-10	IKBKB, PIK3CG, TNF, CACNA1A, MAPK10, IRS1, SOCS1, PRKCE, PIK3R1, PIK3CD, SOCS4, PIK3R3, MAPK1, IRS4, INS, INSR, MTOR, PIK3R5, CACNA1C, MAPK3, PRKCD, IRS2, SLC2A4, PIK3CB, PIK3CA, MAPK9, PIK3R2, SOCS2, SOCS3, PRKCZ, MAPK8	1481	48	6910	3.0133074499212245	2.092665978281616E-7	1.9024237740694616E-9	1.0520549098558263E-6
KEGG_PATHWAY	hsa05132:Salmonella infection	44	2.366863905325444	8.770860455433255E-10	CASP1, CXCL1, MYD88, CDC42, ACTB, TLR4, MAPK12, WASF2, MAPK10, NOS2, IL6, PFN1, RHOG, MAPK11, MAPK1, CXCL2, FOS, MAPK13, TJP1, WASL, IFNG, ARPC1B, ROCK1, FLNA, CCL4, MAPK3, ARPC5, NFKB1, RAB7A, FLNB, RAC1, FLNC, JUN, WASF1, IL1A, RELA, ACTG1, MAPK9, PKN1, CCL3, MAPK14, CXCL8, MAPK8, IL1B	1481	83	6910	2.4734183187849306	2.2804235244588966E-7	2.0544358436680454E-9	1.1464470817124095E-6
KEGG_PATHWAY	hsa05230:Central carbon metabolism in cancer	37	1.9903173749327596	1.0786986104168025E-9	SLC16A3, PFKP, MET, PDGFRA, PIK3CG, MAP2K1, PFKL, AKT3, PIK3R1, PIK3CD, PIK3R3, ERBB2, AKT2, MAPK1, FGFR2, NTRK1, MYC, MTOR, MAP2K2, RET, FLT3, PIK3R5, FGFR3, HIF1A, MAPK3, TP53, KIT, RAF1, PDHB, PIK3CB, PIK3CA, PTEN, KRAS, PIK3R2, EGFR, NRAS, AKT1	1481	64	6910	2.6973961850101285	2.804615902851637E-7	2.5041216877852435E-9	1.4099765910380313E-6
KEGG_PATHWAY	hsa04350:TGF-beta signaling pathway	44	2.366863905325444	1.4298915170118759E-9	TGFBR1, E2F4, PPP2CB, SMURF2, RPS6KB1, PPP2R1B, PPP2R1A, TNF, ID3, CREBBP, SMAD1, TGFB2, SMAD3, SMAD5, CDKN2B, INHBB, SMURF1, SMAD7, ACVR1, SKP1, RBX1, MAPK1, CUL1, RBL1, MYC, BMPR2, THBS1, SMAD9, IFNG, INHBA, EP300, ROCK1, MAPK3, SMAD6, DCN, SMAD2, TGFBR2, SMAD4, PPP2CA, RHOA, LTBP1, TFDP1, SP1, TGFB1	1481	84	6910	2.4439728626089194	3.7177173117797224E-7	3.290015926360468E-9	1.8690240577434736E-6
KEGG_PATHWAY	hsa04727:GABAergic synapse	44	2.366863905325444	2.302750742743778E-9	ADCY9, GNG4, SRC, PRKCA, GNG10, PRKACG, GABARAPL2, CACNA1A, GNG2, ADCY1, ADCY2, GNAI2, GNG12, GNB3, KCNJ6, GABARAPL1, GNB2, ADCY5, PRKACA, GABARAP, GNAI1, PRKACB, GNB4, GNAI3, GNB5, ADCY7, ADCY3, GABRG2, NSF, PRKCG, ADCY4, CACNA1C, GNG8, GNG13, PRKCB, GNG7, ADCY6, ADCY8, GNG3, GABBR2, GNG5, GNAO1, GABBR1, GNGT1	1481	85	6910	2.415220240695873	5.987150211161918E-7	5.251887702506508E-9	3.0099461700849872E-6
KEGG_PATHWAY	hsa04924:Renin secretion	36	1.9365250134480902	5.087378664209889E-9	ITPR3, PRKG2, PLCB1, PRKACG, PPP3CA, PLCB3, ADRB1, ITPR1, GNAI2, PLCB4, PPP3CB, NPR1, CALML5, ADCYAP1R1, CALM3, CALML6, CALML3, ADCY5, PRKACA, GNAI1, PRKACB, PPP3R1, GNAI3, PLCB2, GNAS, PPP3R2, ORAI1, PPP3CC, CTSB, CACNA1C, GNAQ, AGTR1, CREB1, ADCY6, ADRB2, PDE3B	1481	64	6910	2.62449358541526	1.3227175722496654E-6	1.1501899432886376E-8	6.64975811082158E-6
KEGG_PATHWAY	hsa04360:Axon guidance	57	3.066164604626143	6.444243709491212E-9	PPP3CA, CXCR4, PLXNB2, CFL1, SLIT2, NFATC2, RGS3, RAC2, LIMK1, CDK5, PAK3, GNAI1, PPP3R1, ITGB1, PAK1, GSK3B, ROBO1, ROCK1, ABL1, RAC1, CXCL12, RND1, RHOA, LIMK2, FES, CDC42, MET, EFNA1, PAK6, ARHGEF12, GNAI2, DPYSL2, PPP3CB, SEMA4F, MAPK1, RAC3, FYN, PLXNA3, NFATC3, EPHB2, GNAI3, PPP3R2, PAK4, PPP3CC, MAPK3, PAK2, SRGAP2, PLXNA2, SRGAP3, PTK2, NFATC4, SLIT1, EFNA4, NCK1, KRAS, NRAS, EFNA5	1481	127	6910	2.0940841206462966	1.6755019622838319E-6	1.4443994444945929E-8	8.423328501372396E-6
KEGG_PATHWAY	hsa04920:Adipocytokine signaling pathway	38	2.0441097364174285	6.473517799997172E-9	RXRG, IKBKB, TNF, MAPK10, IRS1, POMC, CHUK, AKT3, JAK2, NPY, RXRB, PTPN11, AKT2, IRS4, MTOR, PPARA, NFKBIE, IKBKG, PRKAA1, NFKBIB, NFKBIA, PCK1, NFKB1, TRAF2, CAMKK2, IRS2, TNFRSF1A, SLC2A4, PRKCQ, CPT1A, TRADD, RELA, MAPK9, TNFRSF1B, SOCS3, AKT1, STAT3, MAPK8	1481	70	6910	2.5328446030674256	1.683113225570132E-6	1.4385595159538411E-8	8.461592981845456E-6
KEGG_PATHWAY	hsa05034:Alcoholism	72	3.8730500268961805	8.993871793150569E-9	GNG4, HDAC2, CREB3L4, GNG10, ARAF, GRIN2A, PPP1CA, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, GRB2, NPY, GRIN2D, CREB3, CREB5, ADCY5, GNAI1, GNB4, SHC1, BRAF, SHC2, HDAC7, GNAS, PPP1CB, GNG13, SOS1, CREB1, HDAC8, HDAC5, SHC3, SHC4, DRD2, SOS2, CRH, FOSB, PPP1CC, GRIN1, HDAC3, MAP2K1, GNG2, ADORA2A, GNAI2, HDAC1, GNG12, CALML6, GNB3, PPP1R1B, GNB2, MAPK1, CREB3L2, H2AFX, GNAI3, GNB5, ATF4, GNG8, ATF2, MAPK3, CAMK4, GNG7, CAMKK2, GNG3, RAF1, ATF6B, GNG5, GNAO1, GRIN2B, KRAS, GNGT1, NRAS, BDNF	1481	177	6910	1.8979388640291144	2.338403933599409E-6	1.9817005481037597E-8	1.1755969941962263E-5
KEGG_PATHWAY	hsa05321:Inflammatory bowel disease (IBD)	35	1.8827326519634213	2.2555816634776984E-8	IL21R, IL2RG, IL21, STAT1, TLR4, TNF, IL6, SMAD3, TGFB2, IL17A, STAT6, IL12RB2, NFATC1, IL10, HLA-DMB, IL12A, FOXP3, IFNG, IL4R, NFKB1, HLA-DRB1, IL5, IL2, HLA-DRA, JUN, HLA-DPB1, SMAD2, IL12RB1, RELA, STAT4, IL1A, TLR2, STAT3, TGFB1, IL1B	1481	64	6910	2.551590985820392	5.864495201235442E-6	4.9281615566165726E-8	2.9482906582778412E-5
KEGG_PATHWAY	hsa04932:Non-alcoholic fatty liver disease (NAFLD)	63	3.388918773534158	2.8309826007641816E-8	PIK3CG, MAPK10, IRS1, UQCR10, PIK3R1, SREBF1, PIK3R3, MAP3K5, XBP1, INS, INSR, PPARA, CASP7, CEBPA, ITCH, ERN1, UQCRFS1, BCL2L11, CYC1, CASP8, GSK3B, MAP3K11, RAC1, FASLG, TNFRSF1A, JUN, BAX, DDIT3, RELA, MAPK9, PIK3R2, BID, TGFB1, SOCS3, IL1B, MAPK8, CDC42, IKBKB, TNF, IL6, AKT3, PIK3CD, AKT2, GSK3A, PRKAA1, NDUFV1, NDUFS3, ATF4, PIK3R5, NFKB1, TRAF2, CYCS, IRS2, UQCRC1, PIK3CB, EIF2AK3, PIK3CA, IL1A, FAS, CASP3, EIF2S1, CXCL8, AKT1	1481	151	6910	1.9466442487848286	7.360527785493787E-6	6.13379553815463E-8	3.700402162465366E-5
KEGG_PATHWAY	hsa05134:Legionellosis	31	1.6675632060247445	3.9516457058765225E-8	CASP1, CXCL1, MYD88, HSPA1L, TNF, TLR4, IL6, HSPA8, NFKB2, HSF1, CXCL2, ITGAM, CASP7, IL12A, HSPA6, CASP9, EEF1A1, CASP8, NFKBIA, HSPA2, NFKB1, ITGB2, CYCS, EEF1G, HSPD1, HSPA1A, RELA, CASP3, TLR2, CXCL8, IL1B	1481	54	6910	2.6784955110410884	1.0274226270423625E-5	8.491139347199805E-8	5.1652303778570996E-5
KEGG_PATHWAY	hsa05144:Malaria	29	1.5599784830554062	4.93084166974453E-8	THBS2, MYD88, MET, TLR4, TNF, SELE, IL6, TGFB2, GYPC, HGF, IL10, SELP, THBS1, IL12A, SDC2, IFNG, VCAM1, SDC1, HBA1, CD40, CCL2, ITGB2, TLR9, LRP1, ITGAL, TLR2, CXCL8, TGFB1, IL1B	1481	49	6910	2.7613719356750126	1.2820106475408544E-5	1.050835080063095E-7	6.445145525058038E-5
KEGG_PATHWAY	hsa04140:Regulation of autophagy	25	1.3448090371167294	6.319349143383213E-8	IFNA10, IFNA21, ATG16L1, IFNA5, IFNA1, GABARAPL2, ATG12, GABARAPL1, ATG3, ATG7, IFNA14, ATG5, INS, IFNA17, GABARAP, PRKAA1, IFNG, BECN1, ATG10, PIK3C3, ATG16L2, IFNA4, IFNA16, IFNA8, IFNA6	1481	39	6910	2.9908758808151115	1.643017331665053E-5	1.33579733274658E-7	8.260074888521984E-5
KEGG_PATHWAY	hsa04612:Antigen processing and presentation	38	2.0441097364174285	1.1051757676998256E-7	HSPA4, HSPA1L, CD4, CALR, KIR3DL2, TNF, TAP1, HLA-B, HSPA8, HSP90AA1, HLA-DMB, HLA-A, HLA-E, RFX5, HSPA6, CTSS, RFXANK, KIR3DL1, IFNG, CIITA, PDIA3, KIR2DL2, HLA-F, CTSB, PSME1, HSPA2, KIR2DL4, HLA-DRB1, NFYB, KIR2DL5A, CREB1, HLA-G, HLA-DRA, CD74, HLA-DPB1, HSP90AB1, HSPA1A, NFYA	1481	76	6910	2.3328831870357867	2.8734158710741475E-5	2.3173038887769337E-7	1.4445842110299978E-4
KEGG_PATHWAY	hsa04970:Salivary secretion	41	2.205486820871436	1.646101057883245E-7	ITPR3, ADCY9, PRKG2, PRKCA, PLCB1, PRKACG, PLCB3, ADRB1, ITPR1, ADCY2, ADCY1, PLCB4, CALML5, CALM3, CALML6, CALML3, ATP1A2, SLC12A2, NOS1, FXYD2, ADCY5, PRKACA, ATP1A1, PRKACB, ATP1B1, VAMP2, PLCB2, ADCY7, ADCY3, GNAS, ATP2B4, PRKCG, ADCY4, GNAQ, SLC9A1, PRKCB, PRKG1, ADCY6, ADCY8, ADRB2, ATP1A3	1481	86	6910	2.2243769922899364	4.279771517401443E-5	3.423889896048138E-7	2.151631343316751E-4
KEGG_PATHWAY	hsa05206:MicroRNAs in cancer	99	5.325443786982249	1.7099251148873587E-7	CCND1, CDKN2A, MMP9, SOCS1, MDM2, PLCG2, APC, CDKN1A, MAP2K2, HNRNPK, PDGFB, BCL2, BCL2L11, E2F1, PTGS2, ROCK1, CCNE1, MCL1, SOS1, PDGFA, EZH2, SHC4, RHOA, SOS2, CDKN1B, E2F3, MDM4, IKBKB, PRKCA, CREBBP, MAP2K1, TGFB2, ATM, TNXB, NOTCH1, MYC, MTOR, NOTCH3, UBE2I, WNT3A, FGFR3, PLCG1, IRS2, RAF1, RDX, RPS6KA5, KRAS, EGFR, NRAS, STAT3, PIM1, ITGA5, CCNE2, DDIT4, PDGFRA, IRS1, PRKCE, NOTCH2, EZR, GRB2, CDC25A, CDK6, TIMP3, CDC25C, SHC1, ABL1, PRKCB, ITGB3, DNMT3B, TP53, STMN1, NOTCH4, VEGFA, PTEN, PLAU, ZEB1, CCND2, DNMT3A, MET, MAPK7, CRKL, BRCA1, ERBB2, VIM, MARCKS, BMPR2, THBS1, CRK, EP300, PAK4, PRKCG, NFKB1, BAK1, ABCB1, TNR, ERBB3, CASP3, CCNG1, CD44	1481	285	6910	1.6207398983617045	4.445706854194764E-5	3.5284165833537884E-7	2.2350561728057272E-4
KEGG_PATHWAY	hsa05143:African trypanosomiasis	22	1.183431952662722	1.8786439223653836E-7	IFNG, VCAM1, PLCB2, MYD88, HBA1, PRKCA, PLCB1, PRKCG, TNF, GNAQ, PLCB3, SELE, PRKCB, IL6, TLR9, PLCB4, FASLG, IL10, FAS, APOA1, IL12A, IL1B	1481	33	6910	3.1105109160477156	4.884355369172422E-5	3.846042297972474E-7	2.455589564687166E-4
KEGG_PATHWAY	hsa05020:Prion diseases	22	1.183431952662722	1.8786439223653836E-7	CCL5, C8B, C9, ELK1, PRKACG, STIP1, NCAM1, MAP2K1, MAPK3, IL6, EGR1, PRNP, BAX, IL1A, MAPK1, FYN, HSPA5, LAMC1, PRKACA, MAP2K2, PRKACB, IL1B	1481	33	6910	3.1105109160477156	4.884355369172422E-5	3.846042297972474E-7	2.455589564687166E-4
KEGG_PATHWAY	hsa05320:Autoimmune thyroid disease	28	1.506186121570737	1.1623385887703096E-6	IFNA10, IFNA21, IFNA5, IFNA1, HLA-B, IFNA14, IL10, HLA-DMB, IFNA17, HLA-E, HLA-A, HLA-F, CD40, HLA-DRB1, TG, FASLG, IL5, HLA-DRA, HLA-G, IL2, HLA-DPB1, TSHR, FAS, CGA, IFNA4, IFNA16, IFNA6, IFNA8	1481	52	6910	2.5123357398846933	3.0216254842707624E-4	2.360998843542461E-6	0.0015192925534535107
KEGG_PATHWAY	hsa05217:Basal cell carcinoma	29	1.5599784830554062	1.241474824112803E-6	WNT3A, TCF7L1, FZD6, FZD4, TCF7, GLI3, GSK3B, GLI2, AXIN1, SUFU, WNT10A, AXIN2, WNT5B, CTNNB1, FZD10, DVL3, TP53, FZD2, FZD5, APC, DVL2, WNT1, DVL1, FZD7, LEF1, FZD9, GLI1, FZD8, TCF7L2	1481	55	6910	2.4601313608741022	3.2273156560769234E-4	2.502195742715152E-6	0.0016227307369054422
KEGG_PATHWAY	hsa04623:Cytosolic DNA-sensing pathway	32	1.7213555675094134	1.36210284187138E-6	IFNA10, CASP1, TBK1, IFNA21, IFNA5, IFNA1, ZBP1, IKBKB, IKBKE, IRF7, IL6, CHUK, RIPK1, IFNA14, TMEM173, IFNA17, IKBKG, CCL5, NFKBIB, NFKBIA, IFNB1, CCL4, NFKB1, MAVS, IRF3, DDX58, RELA, IFNA4, IFNA16, IFNA6, IFNA8, IL1B	1481	64	6910	2.3328831870357867	3.5408427743399695E-4	2.7242038284081005E-6	0.0017804022248602003
KEGG_PATHWAY	hsa05130:Pathogenic Escherichia coli infection	27	1.4523937600860677	2.8791139483714073E-6	TUBB4A, TUBB, CDC42, TUBA1A, PRKCA, ACTB, TLR4, CTNNB1, TUBB4B, CDH1, EZR, TUBA4A, TUBA1C, FYN, WASL, TUBB3, ARHGEF2, ITGB1, ARPC1B, ROCK1, ARPC5, ABL1, RHOA, ACTG1, TUBB2A, NCK1, NCL	1481	51	6910	2.4701116098025975	7.482905950334517E-4	5.714263858203061E-6	0.0037632503132156714
KEGG_PATHWAY	hsa05416:Viral myocarditis	29	1.5599784830554062	3.105265795236901E-6	CCND1, ACTB, HLA-B, CAV1, RAC2, HLA-DMB, FYN, RAC3, HLA-A, HLA-E, DAG1, CASP9, HLA-F, CD40, CASP8, EIF4G1, HLA-DRB1, ABL1, MYH7, ITGB2, RAC1, CYCS, HLA-G, HLA-DRA, HLA-DPB1, ITGAL, ACTG1, CASP3, BID	1481	57	6910	2.3738109622469405	8.070445245692559E-4	6.116423418300876E-6	0.004058844747278911
KEGG_PATHWAY	hsa04640:Hematopoietic cell lineage	38	2.0441097364174285	3.499753147971295E-6	IL9R, KITLG, CD59, ITGA5, CSF1R, CD4, IL7R, IL1R2, IL11, TNF, IL6, ITGA3, IL1R1, ITGA2, CSF3R, ITGAM, IL4R, FLT3, MME, TFRC, CD2, HLA-DRB1, ITGB3, KIT, IL5, HLA-DRA, CSF1, EPOR, ITGA1, IL5RA, IL3RA, IL1A, IL2RA, ITGA6, CD44, CD3E, GP1BA, IL1B	1481	85	6910	2.085872026055527	9.09523543241253E-4	6.841611263297409E-6	0.0045744621545384945
KEGG_PATHWAY	hsa05010:Alzheimer's disease	62	3.335126412049489	5.414468170583284E-6	ITPR3, GAPDH, SNCA, PPP3CA, PLCB3, PSEN2, GRIN2A, PLCB4, UQCR10, CALML5, CALM3, CALML3, GRIN2D, CDK5, CDK5R1, CASP7, CASP9, PPP3R1, ERN1, UQCRFS1, PLCB2, MME, CYC1, CASP8, BAD, GSK3B, ADAM17, TNFRSF1A, LRP1, APOE, BID, BACE1, IL1B, PSEN1, PLCB1, GRIN1, TNF, ITPR1, ATP2A2, PPP3CB, CALML6, FADD, NOS1, MAPK1, MAPT, PPP3R2, NDUFV1, NDUFS3, PPP3CC, CACNA1C, GNAQ, MAPK3, CAPN1, APP, ATP2A3, CYCS, UQCRC1, EIF2AK3, FAS, CASP3, GRIN2B, ATF6	1481	168	6910	1.721889971383557	0.00140677509842968	1.0505657766723964E-5	0.0070770687127907905
KEGG_PATHWAY	hsa04120:Ubiquitin mediated proteolysis	53	2.850995158687466	6.187515558458921E-6	BIRC6, ANAPC1, SMURF2, CDC16, CDC20, CUL5, SOCS1, UBE2D3, MDM2, PIAS3, UBE4A, CUL1, CDC27, CUL3, ITCH, FBXW11, ANAPC10, ANAPC11, PIAS2, FZR1, UBE2L3, UBE2B, CBLB, PIAS4, UBE2J2, NEDD4L, UBE2H, SOCS3, PIAS1, ANAPC5, ANAPC4, ANAPC2, UBE2D2, BTRC, CBL, PRPF19, BIRC3, SMURF1, BIRC2, TRIM37, BRCA1, SKP1, RBX1, UBE2I, TRAF6, CDC26, MAP3K1, HUWE1, UBE2K, UBE2W, CBLC, STUB1, PML	1481	137	6910	1.805004509677324	0.0016074656631842599	1.1916662494670938E-5	0.008087455144234479
KEGG_PATHWAY	hsa04512:ECM-receptor interaction	38	2.0441097364174285	6.7839377594626806E-6	COL4A3, FN1, THBS2, ITGA5, SPP1, COL4A5, RELN, COL4A1, ITGA3, TNXB, ITGB8, ITGAV, ITGA2, COL2A1, ITGB7, LAMC1, THBS1, DAG1, HSPG2, SDC1, COL6A3, ITGB1, COL4A2, COL1A1, LAMA1, ITGB3, COL1A2, COL4A6, LAMA5, ITGA1, TNR, VTN, VWF, SDC4, ITGA6, IBSP, CD44, GP1BA	1481	87	6910	2.0379209449967792	0.0017622751667043524	1.2969252665584463E-5	0.00886698292968946
KEGG_PATHWAY	hsa05414:Dilated cardiomyopathy	37	1.9903173749327596	7.297373257583427E-6	IGF1, ITGA5, ADCY9, MYL2, ACTB, PRKACG, TNF, ADRB1, TGFB2, ADCY1, ADCY2, ITGA3, ITGB8, ITGAV, ITGA2, ITGB7, ACTC1, ADCY5, PRKACA, EMD, DAG1, PRKACB, ADCY7, ADCY3, GNAS, ITGB1, PLN, ADCY4, CACNA1C, ITGB3, RYR2, ADCY6, ADCY8, ITGA1, ACTG1, ITGA6, TGFB1	1481	84	6910	2.055158998102955	0.00189552518839331	1.3848984172781797E-5	0.009538042047108064
KEGG_PATHWAY	hsa04961:Endocrine and other factor-regulated calcium reabsorption	24	1.2910166756320602	1.0196419071668797E-5	PLCB2, ADCY9, GNAS, PRKCA, PLCB1, VDR, PRKCG, PRKACG, GNAQ, PLCB3, PRKCB, BDKRB2, PLCB4, ADCY6, ESR1, ATP1A2, ATP1A3, FXYD2, CLTC, TRPV5, PRKACA, ATP1A1, PRKACB, ATP1B1	1481	45	6910	2.4884087328381725	0.0026475714586267074	1.9210558043103454E-5	0.013327010796260197
KEGG_PATHWAY	hsa04972:Pancreatic secretion	39	2.097902097902098	1.572113412635342E-5	PLA2G2A, ITPR3, ADCY9, PRKCA, PLCB1, PLCB3, ITPR1, ATP2A2, ADCY2, ADCY1, PLCB4, CFTR, ATP1A2, SLC12A2, FXYD2, ADCY5, ATP1A1, ATP1B1, RAP1A, RAP1B, KCNQ1, PLCB2, ADCY7, ADCY3, GNAS, ATP2B4, PRKCG, GNAQ, ADCY4, SLC9A1, PRKCB, PLA2G10, ATP2A3, RYR2, RAC1, ADCY6, ADCY8, ATP1A3, RHOA	1481	93	6910	1.9566117052558212	0.00407918443542199	2.9406236716100764E-5	0.020547285940941684
KEGG_PATHWAY	hsa05340:Primary immunodeficiency	19	1.0220548682087143	5.144824054286181E-5	IL2RG, CIITA, LCK, CD40, PTPRC, ORAI1, CD4, IL7R, TAP1, BTK, RAG1, BLNK, UNG, ZAP70, RFX5, IKBKG, ADA, CD3E, RFXANK	1481	34	6910	2.6073400325694087	0.013287813719656927	9.554462569805189E-5	0.06722757951875824
KEGG_PATHWAY	hsa04962:Vasopressin-regulated water reabsorption	22	1.183431952662722	9.094861598802645E-5	VAMP2, ADCY3, ADCY9, GNAS, NSF, ARHGDIA, CREB3L4, PRKACG, RAB5B, CREB1, RAB5C, ADCY6, RAB5A, CREB3L1, CREB3L3, CREB3, DCTN1, CREB5, RAB11B, PRKACA, PRKACB, CREB3L2	1481	44	6910	2.3328831870357867	0.023370299367024172	1.677002313302811E-4	0.1188145189295775
KEGG_PATHWAY	hsa05323:Rheumatoid arthritis	35	1.8827326519634213	1.6354586841014855E-4	TNFRSF11A, IL11, TNFSF11, TLR4, TNF, IL6, TGFB2, IL17A, ATP6V0A1, TNFSF13, HLA-DMB, CXCL5, FOS, ANGPT1, IFNG, CCL5, CCL2, FLT1, HLA-DRB1, ITGB2, HLA-DRA, JUN, CSF1, HLA-DPB1, CXCL12, MMP3, ITGAL, IL1A, VEGFA, TLR2, CCL3, CXCL8, TGFB1, MMP1, IL1B	1481	88	6910	1.855702535142103	0.041633880458422756	2.994298331229217E-4	0.21356138905127553
KEGG_PATHWAY	hsa04913:Ovarian steroidogenesis	23	1.237224314147391	1.9236676400321878E-4	ADCY7, IGF1, ADCY3, ADCY9, GNAS, FSHB, LDLR, PTGS2, PRKACG, ADCY4, ADCY2, ADCY1, ADCY6, ADCY8, IGF1R, CYP19A1, FSHR, ADCY5, INS, CGA, INSR, PRKACA, PRKACB	1481	49	6910	2.1900536041560446	0.04878976151217762	3.4973022805295795E-4	0.251152596111337
KEGG_PATHWAY	hsa05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC)	29	1.5599784830554062	4.0738492016954343E-4	ITGA5, TCF7, CDH2, ACTB, CTNNA1, CTNNB1, ACTN2, ITGA3, ACTN1, ITGB8, ITGAV, ITGA2, ITGB7, ACTN4, LEF1, EMD, DAG1, TCF7L2, TCF7L1, ITGB1, CACNA1C, JUP, ITGB3, RYR2, CTNNA3, ITGA1, ACTG1, ITGA6, CTNNA2	1481	71	6910	1.9057355612405016	0.10052287816361694	7.354354085147286E-4	0.531189158425216
KEGG_PATHWAY	hsa04320:Dorso-ventral axis formation	15	0.8068854222700376	4.7065107147112957E-4	ETV6, ETS1, MAPK3, MAP2K1, SOS1, NOTCH1, NOTCH2, GRB2, NOTCH4, MAPK1, ETS2, SOS2, KRAS, EGFR, NOTCH3	1481	27	6910	2.5920924300397625	0.11520392498453491	8.437685458316802E-4	0.6134477384459824
KEGG_PATHWAY	hsa05332:Graft-versus-host disease	17	0.914470145239376	4.989942115431003E-4	IFNG, HLA-F, TNF, HLA-DRB1, IL6, HLA-B, FASLG, IL2, HLA-G, HLA-DRA, HLA-DPB1, IL1A, HLA-DMB, FAS, HLA-A, HLA-E, IL1B	1481	33	6910	2.403576616945962	0.12170335254661913	8.884467079386393E-4	0.6502790776582446
KEGG_PATHWAY	hsa05330:Allograft rejection	18	0.9682625067240451	7.347419866799498E-4	IFNG, CD40, HLA-F, TNF, HLA-DRB1, HLA-B, IL5, FASLG, IL2, HLA-G, HLA-DRA, HLA-DPB1, IL10, HLA-DMB, FAS, HLA-A, HLA-E, IL12A	1481	37	6910	2.269832290088873	0.1739526072398485	0.0012991766369091495	0.9561404727291278
KEGG_PATHWAY	hsa04940:Type I diabetes mellitus	19	1.0220548682087143	0.0014125664450210346	IFNG, HLA-F, TNF, HLA-DRB1, HLA-B, FASLG, IL2, HLA-G, HLA-DRA, HLA-DPB1, HSPD1, IL1A, HLA-DMB, FAS, INS, HLA-A, HLA-E, IL12A, IL1B	1481	42	6910	2.110703835889521	0.30755531055942154	0.002480209152093127	1.830718560266098
KEGG_PATHWAY	hsa04141:Protein processing in endoplasmic reticulum	54	2.9047875201721354	0.001465115593319334	NFE2L2, MAPK10, HSPBP1, UBE2D3, HSPA8, MAP3K5, EIF2AK1, XBP1, EIF2AK4, CUL1, BCAP31, BCL2, ERN1, UBE2J2, RAD23B, PRKCSH, HSP90AB1, RRBP1, BAX, RAD23A, DDIT3, MAPK9, P4HB, MAPK8, UBE2D2, HSPA1L, CALR, DNAJB1, PDIA4, HSP90AA1, HSP90B1, SKP1, RBX1, HSPA5, BAG1, DNAJC3, HSPA6, PDIA3, UBQLN4, ATF4, EIF2AK2, HSPA2, CAPN1, TRAF2, BAK1, PDIA6, ATF6B, EIF2AK3, HSPA1A, EIF2S1, ATF6, MAP2K7, STUB1, HSPH1	1481	169	6910	1.4908365928986094	0.31696513947085714	0.002555182167976011	1.898222491370516
KEGG_PATHWAY	hsa04340:Hedgehog signaling pathway	14	0.7530930607853685	0.0018160092938954437	FBXW11, GLI3, GLI2, GSK3B, BTRC, PRKACG, SUFU, CSNK1A1, CSNK1D, CSNK1E, PRKACA, GLI1, PRKACB, CSNK1G2	1481	27	6910	2.419286268037112	0.37661542907541723	0.003145653112060276	2.347878198793485
KEGG_PATHWAY	hsa04145:Phagosome	49	2.63582571274879	0.002377959935109318	TUBB4A, THBS2, TUBB, ITGA5, TUBA1A, CALR, ACTB, TLR4, SFTPD, TAP1, NCF1, RAB5B, HLA-B, TUBB4B, ATP6V0A1, MRC1, ITGAV, ITGA2, TUBA4A, NOS1, PLA2R1, TUBA1C, HLA-DMB, ITGAM, HLA-A, HLA-E, THBS1, CTSS, TUBB3, HLA-F, ITGB1, TFRC, HLA-DRB1, CD209, RAB7A, ITGB2, ITGB3, RAB5C, RAC1, HLA-DRA, HLA-G, HLA-DPB1, RAB5A, NCF4, PIK3C3, ACTG1, TUBB2A, CLEC4M, TLR2	1481	153	6910	1.4942650479052753	0.4615205048005341	0.004090985586898688	3.064031415303836
KEGG_PATHWAY	hsa04710:Circadian rhythm	15	0.8068854222700376	0.0026137959560260044	FBXW11, PRKAA1, BTRC, CSNK1D, PER1, CREB1, CLOCK, ARNTL, PER2, SKP1, RBX1, CSNK1E, CUL1, PER3, CRY1	1481	31	6910	2.2576288906797934	0.49362442910575655	0.004466814044428169	3.363134786493671
KEGG_PATHWAY	hsa03015:mRNA surveillance pathway	31	1.6675632060247445	0.006779268000645355	RNPS1, PPP2R2D, PPP2R2A, PPP2CB, PPP1CC, UPF2, PPP2R1B, PPP2R1A, PPP1CA, PPP2R2C, FIP1L1, PPP2R5C, PPP2R3C, CPSF7, PNN, PPP2R2B, PPP2R5D, CPSF2, UPF1, PABPN1, WDR82, PPP2R5A, PPP1CB, PABPC4, SRRM1, PPP2R3A, PAPOLA, DAZAP1, PPP2R5B, PPP2CA, PPP2R5E	1481	91	6910	1.5894368966617447	0.8294303262769551	0.011492996855583804	8.507588282543866
KEGG_PATHWAY	hsa04330:Notch signaling pathway	19	1.0220548682087143	0.007853957758376093	NCOR2, EP300, HDAC2, PSEN1, SNW1, CREBBP, PSEN2, DVL3, ADAM17, HDAC1, NOTCH1, RBPJL, NOTCH2, CTBP1, MAML2, NOTCH4, DVL2, DVL1, NOTCH3	1481	48	6910	1.8468658564033311	0.8712767152648231	0.013224057966492286	9.793171124393652
KEGG_PATHWAY	hsa04672:Intestinal immune network for IgA production	18	0.9682625067240451	0.014310150082136014	CD40, MAP3K14, CXCR4, HLA-DRB1, IL6, TNFRSF17, IL5, IL2, HLA-DRA, HLA-DPB1, CXCL12, TNFSF13, ITGB7, IL10, IL15RA, HLA-DMB, CCR10, TGFB1	1481	47	6910	1.7868892496444322	0.9764237917728898	0.02388759518412964	17.17170993024012
KEGG_PATHWAY	hsa04976:Bile secretion	24	1.2910166756320602	0.01436520564946311	NR0B2, ADCY7, ADCY3, ADCY9, GNAS, SLC22A1, LDLR, PRKACG, ADCY4, SLC9A1, ADCY2, ADCY1, ADCY6, ADCY8, CFTR, ATP1A2, ABCB1, ATP1A3, FXYD2, ADCY5, PRKACA, ATP1A1, PRKACB, ATP1B1	1481	69	6910	1.6228752605466343	0.9767637070253271	0.023827181583539025	17.232161147690007
KEGG_PATHWAY	hsa04973:Carbohydrate digestion and absorption	16	0.8606777837547067	0.023366876181408015	PIK3R5, PIK3CG, AKT3, PIK3R1, PIK3CD, ATP1A2, PIK3R3, PIK3CB, ATP1A3, AKT2, PIK3CA, FXYD2, PIK3R2, ATP1A1, AKT1, ATP1B1	1481	42	6910	1.7774348091701233	0.9978611665489464	0.03839932889067954	26.586004846203913
KEGG_PATHWAY	hsa05110:Vibrio cholerae infection	19	1.0220548682087143	0.02345368779245851	KCNQ1, ADCY3, GNAS, ADCY9, PRKCA, PRKCG, ACTB, PRKACG, PLCG1, PRKCB, ATP6V0A1, PDIA4, CFTR, PLCG2, SLC12A2, ACTG1, PRKACA, PRKACB, TJP1	1481	53	6910	1.6726332284407528	0.9979100325642074	0.038301679238866626	26.6712567415492
KEGG_PATHWAY	hsa04514:Cell adhesion molecules (CAMs)	41	2.205486820871436	0.033091233348799126	CD4, CDH2, ICAM3, NCAM1, SELE, SELPLG, HLA-B, NRCAM, ITGB8, PTPRF, CDH1, ITGAV, ITGB7, JAM2, HLA-DMB, NFASC, SELP, ITGAM, HLA-A, HLA-E, SDC2, VCAM1, SDC1, CNTN1, ITGB1, CD40, HLA-F, PTPRC, CD2, JAM3, HLA-DRB1, ITGB2, HLA-DRA, HLA-G, HLA-DPB1, ICAM2, ITGAL, SDC4, ITGA6, VCAN, F11R	1481	142	6910	1.3471578967389752	0.9998414269267492	0.05354041894921935	35.58714788709912
KEGG_PATHWAY	hsa04070:Phosphatidylinositol signaling system	30	1.6137708445400751	0.034731835687576415	ITPR3, PRKCA, PLCB1, PIK3CG, PLCB3, INPPL1, ITPR1, PLCB4, CALML5, CALML6, PIK3R1, CALM3, PIK3CD, CALML3, PIK3C2A, PIK3R3, PLCG2, PLCB2, PLCE1, PIK3R5, PRKCG, PLCG1, PRKCB, INPP5K, INPP5D, PIK3CB, PIK3C3, PIK3CA, PIK3R2, PTEN	1481	98	6910	1.4282958287974203	0.9998980292652205	0.055823966799954494	37.00118144619103
KEGG_PATHWAY	hsa05410:Hypertrophic cardiomyopathy (HCM)	24	1.2910166756320602	0.057692525766117435	PRKAA1, IGF1, ITGA5, MYL2, ITGB1, TNF, ACTB, CACNA1C, IL6, TGFB2, ITGB3, RYR2, ITGA3, ITGB8, ITGAV, ITGA2, ITGA1, ITGB7, ACTC1, ACTG1, ITGA6, EMD, DAG1, TGFB1	1481	78	6910	1.4356204227912535	0.9999998049772255	0.09150297106378091	54.009341790687046