Category	Term	Count	%	Pvalue	Genes	List Total	Pop Hits	Pop Total	Fold Enrichment	Bonferroni	Benjamini	FDR
KEGG_PATHWAY	hsa05200:Pathways in cancer	270	14.523937600860679	7.005133311698848E-81	ARNT, RASSF5, ADCY9, CDKN2A, ARAF, CXCR4, CDKN2B, WNT5B, ADCY1, ADCY2, FZD2, MDM2, PLCG2, RUNX1T1, FZD5, LEF1, PRKACB, PDGFB, CASP9, GNA11, BAD, ROCK1, GNA13, BCL2L1, LAMA5, BAX, RHOA, RELA, EGF, BID, BDKRB1, TGFB1, CDKN1B, E2F3, COL4A3, CBL, PLCB1, PRKCA, CREBBP, ARHGEF12, GNG12, HSP90B1, ITGAV, AKT2, FGFR2, RAC3, FZD7, MYC, PPARG, FOS, RET, WNT3A, FGF13, GLI3, GLI2, PLCG1, JUP, MAPK3, CDK2, GNG3, RAF1, GNG5, PTK2, BRCA2, KRAS, EGFR, GNGT1, STAT3, NRAS, AKT1, TGFBR1, IGF1, GNG4, GNG10, AXIN1, PDGFRA, PLCB3, CTNNA1, COL4A5, GRB2, ADCY5, GNAI1, TCF7L2, TCF7L1, GNAS, PRKCB, TRAF4, JUN, TGFBR2, PGF, PIK3R2, F2R, CCDC6, VEGFC, VEGFB, MITF, GNAI2, HDAC1, AR, HSP90AA1, RARA, PIK3CD, GNB2, HGF, STAT5B, PAX8, RBX1, GNB5, FLT3, JAK1, EP300, PIK3R5, PRKCG, GNG8, GNAQ, NFKB1, LAMA1, CXCL8, CCND1, FZD4, TCF7, EPAS1, PRKACG, MMP9, FGF10, MAPK10, SMAD3, PLCB4, ITGA3, COL4A1, FGF2, BCR, RAC2, APC, CDKN1A, CKS2, MAP2K2, FZD9, CEBPA, GNB4, BRAF, BCL2, RB1, E2F1, ADCY7, ITGB1, CASP8, COL4A2, NFKBIA, PTGS2, CCNE1, RUNX1, ADCY4, GNG13, AXIN2, SOS1, PDGFA, TFG, CXCL12, HSP90AB1, MAPK9, DVL2, DVL1, SOS2, MAPK8, ARHGEF1, CDC42, IKBKB, CKS1B, MLH1, MAP2K1, SUFU, NOS2, TGFB2, IL6, TRAF5, CTNNB1, FGF1, AKT3, ITGA2, MAPK1, MTOR, GLI1, TRAF3, GNAI3, ADCY3, FGFR3, HIF1A, TRAF2, AGTR1, GNG7, BDKRB2, DVL3, ADCY6, CYCS, SMAD2, PIK3CB, CTNNA3, MMP2, PIK3CA, CDK4, FAS, FGF12, MMP1, CTNNA2, FZD6, FGF3, STAT1, CCNE2, HDAC2, PIK3CG, WNT10A, FOXO1, STAT5A, PIK3R1, CDH1, PIK3R3, DAPK1, CDK6, CSF3R, PRKACA, PLCB2, PIAS2, GSK3B, CBLB, FGF7, SPI1, ABL1, RAC1, TP53, FASLG, FGF18, COL4A6, IGF1R, VEGFA, PTEN, KITLG, FN1, CSF1R, RXRG, MET, BIRC3, GNG2, CHUK, GNB3, CRKL, BIRC2, CTBP1, NFKB2, RXRB, ERBB2, FADD, WNT1, NTRK1, LAMC1, TRAF6, FZD8, IKBKG, CRK, PPARD, NKX3-1, FZD10, ADCY8, KIT, CBLC, SMAD4, ZBTB16, CASP3, ITGA6, PML	1481	388	5892	2.7684693401644194	1.8213346610417006E-78	1.8213346610417006E-78	9.156472685538834E-78
KEGG_PATHWAY	hsa04151:PI3K-Akt signaling pathway	233	12.533620225927919	7.427916639951395E-68	PPP2R2D, TLR4, RPS6, MDM2, INS, PDGFB, CASP9, BAD, MCL1, BCL2L1, LAMA5, ITGA1, YWHAE, CRTC2, PPP2CA, RELA, IL3RA, EGF, TLR2, CDKN1B, NGF, IFNA8, COL4A3, PRKCA, EFNA1, GNG12, HSP90B1, ITGAV, AKT2, SYK, FGFR2, MYC, YWHAZ, FGF13, PPP2R3A, MAPK3, CDK2, GNG3, RAF1, OSMR, GNG5, PTK2, YWHAH, MYB, KRAS, IBSP, EGFR, GNGT1, AKT1, NRAS, ITGA5, IGF1, DDIT4, GNG4, PPP2CB, GNG10, NGFR, PPP2R1B, PDGFRA, PPP2R1A, YWHAB, SPP1, COL4A5, RELN, GRB2, CREB3L3, CREB3, PPP2R3C, CREB5, IFNAR1, ITGB3, COL1A2, CREB1, VWF, PGF, PIK3R2, IFNA4, F2R, IFNA16, IFNA6, IFNA10, VEGFC, IFNA21, IFNA5, VEGFB, CCND2, IFNA1, RPS6KB1, IL7R, YWHAG, HSP90AA1, PIK3CD, HGF, GNB2, IFNA14, IFNA17, CCND3, GNB5, JAK1, ATF4, PIK3R5, IFNB1, GNG8, EIF4EBP1, ATF2, NFKB1, LAMA1, PRLR, TCL1A, VTN, EFNA4, EFNA5, CCND1, PDGFD, CREB3L4, TSC2, FGF10, ITGA3, COL4A1, PPP2R2C, ITGB8, FGF2, PDPK1, COL2A1, ITGB7, CHRM2, CDKN1A, INSR, PHLPP2, MAP2K2, GNB4, BCL2, BCL2L11, ANGPT2, IL4R, ITGB1, COL6A3, COL4A2, CCNE1, GNG13, SOS1, PDGFA, PDGFC, FOXO3, HSP90AB1, IL2RB, SOS2, IL2RA, PPP2R5E, IKBKB, MAP2K1, IL6, FGF1, TNXB, AKT3, ITGA2, JAK2, MAPK1, MTOR, CREB3L2, PRKAA1, GYS2, PPP2R5A, FGFR3, COL1A1, ANGPT4, GNG7, PPP2R5B, IL2, CSF1, PIK3CB, PIK3CA, CDK4, IFNAR2, PKN1, FGF12, IL2RG, FGF3, PPP2R2A, CCNE2, PIK3CG, IRS1, JAK3, PIK3R1, CREB3L1, PIK3R3, RHEB, PPP2R2B, CDK6, CSF3R, GYS1, CSH2, ANGPT1, GSK3B, PHLPP1, FGFR4, FGF7, FLT1, RAC1, TP53, FASLG, TSC1, FGF18, COL4A6, IGF1R, KDR, VEGFA, PTEN, PRL, THBS2, FN1, KITLG, CSF1R, GHR, MET, GNG2, CHUK, GNB3, PPP2R5C, BRCA1, NOS3, PPP2R5D, LAMC1, NR4A1, THBS1, IKBKG, PCK1, EIF4E, KIT, ATF6B, EPOR, TNR, ITGA6	1481	338	5892	2.7425016680717094	1.9312583263873626E-65	9.656291631936813E-66	9.709096572165028E-65
KEGG_PATHWAY	hsa05161:Hepatitis B	128	6.885422270037654	7.963998947975213E-60	CCND1, TBK1, PTK2B, ELK1, CREB3L4, TLR4, MMP9, MAPK10, NFATC2, TICAM2, CDKN1A, MAP2K2, HSPG2, CASP9, BCL2, RB1, E2F1, BAD, CASP8, NFKBIA, CCNE1, CCNA2, MAVS, TIRAP, STAT2, BAX, DDX58, RELA, MAPK9, MAP2K4, TLR2, CDKN1B, E2F3, TGFB1, MAPK8, IFNA8, MYD88, IKBKB, PRKCA, CREBBP, MAP2K1, IKBKE, TGFB2, IL6, IRF7, AKT3, NFATC1, AKT2, MAPK1, MYC, FOS, CREB3L2, YWHAZ, MAP3K1, CCNA1, MAPK3, CDK2, IRF3, CYCS, RAF1, PIK3CB, PIK3CA, CDK4, STAT4, FAS, KRAS, STAT3, AKT1, NRAS, TGFBR1, STAT1, CCNE2, SRC, PIK3CG, YWHAB, TICAM1, STAT6, STAT5A, PIK3R1, CREB3L1, CREB3L3, GRB2, PIK3R3, CREB3, CREB5, CDK6, IFIH1, IFNAR1, PRKCB, CREB1, FASLG, TP53, JUN, PIK3R2, PTEN, IFNA4, IFNA16, VDAC3, IFNA6, IFNA10, IFNA21, IFNA5, IFNA1, TNF, CHUK, PIK3CD, STAT5B, FADD, IFNA14, NFATC3, IFNA17, PCNA, IKBKG, JAK1, PIK3R5, ATF4, EP300, IFNB1, PRKCG, ATF2, EGR2, NFKB1, CASP10, ATF6B, SMAD4, NFATC4, CASP3, CXCL8	1481	143	5892	3.5610790290061054	2.0706397264735554E-57	6.902132421578519E-58	1.0409814573123429E-56
KEGG_PATHWAY	hsa05166:HTLV-I infection	183	9.84400215169446	3.158890910940887E-58	FZD4, CCND1, ADCY9, ANAPC1, ELK1, RRAS2, MAP3K14, CDC20, PRKACG, CDKN2A, SMAD3, WNT5B, CDKN2B, ADCY2, ADCY1, EGR1, NFATC2, FDPS, FZD2, IL1R1, XBP1, FZD5, APC, HLA-DMB, CDKN1A, FZD9, PRKACB, PDGFB, RB1, E2F1, ADCY7, TLN1, NFKBIA, ADCY4, PDGFA, HLA-DRA, BCL2L1, RELB, IL2RB, BAX, CRTC2, RELA, DVL2, MAP2K4, DVL1, IL2RA, E2F3, TGFB1, LCK, IKBKB, VDAC2, IL1R2, CREBBP, POLD2, IL6, TGFB2, CTNNB1, ATM, AKT3, NFATC1, POLD1, AKT2, ETS2, FZD7, MYC, SRF, FOS, CREM, WNT3A, ADCY3, CD40, MAP3K1, ETS1, TBP, TBPL1, KAT5, SLC25A4, DVL3, ADCY6, IL2, SMAD2, PIK3CB, PIK3CA, CDK4, MYBL2, RRAS, MYB, KRAS, AKT1, NRAS, FZD6, IL2RG, TGFBR1, TERT, CDC16, PDGFRA, PPP3CA, PIK3CG, WNT10A, STAT5A, JAK3, PIK3R1, PIK3R3, POLE3, MRAS, ADCY5, CDC27, RAN, PRKACA, HLA-A, HLA-E, PPP3R1, ELK4, CHEK1, ANAPC10, ANAPC11, TCF3, POLE, GSK3B, POLB, SPI1, ITGB2, CREB1, TNFRSF1A, TP53, HLA-G, HLA-DPB1, JUN, TGFBR2, ITGAL, PIK3R2, FOSL1, CD3E, DLG1, VDAC3, ANAPC5, MAD2L1, ANAPC4, ANAPC2, CCND2, PTTG1, CALR, TNF, PTTG2, HLA-B, PPP3CB, CHUK, SLC25A5, PIK3CD, NFKB2, STAT5B, IL15RA, WNT1, NFATC3, CCND3, PCNA, FZD8, IKBKG, CDC26, VCAM1, ATF1, PPP3R2, BUB3, JAK1, HLA-F, PIK3R5, ATF4, EP300, ATF3, PPP3CC, ATF2, EGR2, CHEK2, HLA-DRB1, NFKB1, NFYB, FZD10, ADCY8, ATR, SMAD4, XPO1, NFATC4, MAP3K3	1481	252	5892	2.8890710909617057	8.213116368446306E-56	2.0532790921115765E-56	4.129014689031314E-55
KEGG_PATHWAY	hsa05205:Proteoglycans in cancer	150	8.068854222700377	7.435846569978435E-53	FZD4, CCND1, RRAS2, ELK1, CAV2, PRKACG, TLR4, MMP9, GPC1, MAPK12, RPS6, ARAF, WNT5B, FGF2, FZD2, MDM2, PDPK1, PLCG2, FZD5, CAMK2A, CDKN1A, CD63, FZD9, MAP2K2, PRKACB, HSPG2, SDC2, BRAF, PAK1, ITGB1, ROCK1, SOS1, FLNB, RHOA, CAMK2G, TWIST1, SOS2, MAPK14, TLR2, CAMK2B, CAV3, CAMK2D, TGFB1, ARHGEF1, CDC42, CBL, PRKCA, GPC3, ANK1, MAP2K1, TGFB2, ERBB4, ITPR1, ARHGEF12, CTNNB1, AKT3, ITGAV, ITGA2, AKT2, PTPN11, MAPK1, FZD7, MYC, MTOR, WNT3A, PLCE1, HIF1A, PLCG1, MAPK3, DCN, RAF1, RDX, PIK3CB, PTK2, PXN, MMP2, PIK3CA, ACTG1, RRAS, SDC4, FAS, KRAS, EGFR, STAT3, AKT1, NRAS, FZD6, ITGA5, IGF1, ITPR3, SRC, PIK3CG, ACTB, WNT10A, ANK2, CAV1, PPP1CA, PIK3R1, EZR, PTPN6, GRB2, PIK3R3, NUDT16L1, MRAS, MAPK11, PRKACA, TIMP3, MAPK13, SDC1, PPP1CB, MSN, CBLB, FLNA, PRKCB, PLAUR, ITGB3, RAC1, FASLG, TP53, IGF1R, KDR, ANK3, VEGFA, PIK3R2, PLAU, FN1, PPP1CC, RPS6KB1, MET, TNF, PIK3CD, HGF, ERBB2, WNT1, FRS2, THBS1, FZD8, PIK3R5, PRKCG, SLC9A1, TFAP4, FZD10, FLNC, GAB1, ESR1, CBLC, VTN, CASP3, ERBB3, CD44	1481	195	5892	3.060302290552122	1.9333201081943932E-50	3.8666402163887863E-51	9.719461854945523E-50
KEGG_PATHWAY	hsa04722:Neurotrophin signaling pathway	101	5.433028509951587	3.0540231017440836E-45	IRAK4, MAPK12, MAPK10, PSEN2, CALML5, CALM3, MAP3K5, PDPK1, PLCG2, CAMK2A, MAP2K2, BCL2, BRAF, MAPKAPK2, SHC2, BAD, NFKBIA, SOS1, IRAK2, FOXO3, YWHAE, BAX, SHC3, SHC4, RHOA, RELA, CAMK2G, MAPK9, SOS2, CAMK2B, MAPK14, CAMK2D, MAPK8, NGF, CDC42, IKBKB, ARHGDIA, MAP2K1, AKT3, MAGED1, PTPN11, AKT2, MAPK1, RAP1A, RAP1B, MAP3K1, PLCG1, MAPK3, RAF1, PIK3CB, PIK3CA, KRAS, TP73, RPS6KA5, MAP2K7, NRAS, AKT1, BDNF, NGFR, PIK3CG, IRS1, PIK3R1, CALML3, GRB2, PIK3R3, MAPK11, SHC1, MAPK13, GSK3B, ABL1, ZNF274, RAC1, TP53, FASLG, RPS6KA1, JUN, RPS6KA6, PIK3R2, PSEN1, RPS6KA2, MAPK7, MAP2K5, CRKL, CALML6, PIK3CD, IRAK1, NTRK1, FRS2, TRAF6, CRK, NFKBIE, ATF4, PIK3R5, RPS6KA3, NFKBIB, RIPK2, NFKB1, PRKCD, CAMK4, GAB1, MAP3K3	1481	115	5892	3.4940668760825533	7.940460064534617E-43	1.3234100107557696E-43	3.9919410335022714E-42
KEGG_PATHWAY	hsa04062:Chemokine signaling pathway	132	7.100591715976331	7.851104362342152E-43	ADCY9, PTK2B, PRKACG, CXCR4, ADCY2, ADCY1, PLCB4, GRK4, RAC2, CCL14, CXCR5, CCR10, CXCL5, PRKACB, GNB4, WASL, BRAF, SHC2, CCL5, ADCY7, PAK1, CCL2, NFKBIA, ROCK1, ADCY4, GNG13, SOS1, FOXO3, CXCL12, STAT2, SHC3, CCL1, SHC4, RHOA, RELA, SOS2, ARRB1, CDC42, PLCB1, IKBKB, MAP2K1, NCF1, CCL17, AKT3, GNG12, JAK2, AKT2, MAPK1, CXCL2, RAP1A, RAP1B, LYN, GNAI3, ADCY3, MAPK3, GRK5, GNG7, GNG3, ADCY6, RAF1, PIK3CB, GNG5, PTK2, PXN, PIK3CA, CCL26, KRAS, GNGT1, STAT3, AKT1, NRAS, PF4, STAT1, GNG4, SRC, GNG10, PPBP, PIK3CG, PLCB3, JAK3, PIK3R1, GRB2, PIK3R3, PREX1, CCL11, ADCY5, PRKACA, CCR3, GNAI1, SHC1, PLCB2, GSK3B, VAV2, RAC1, ITK, ARRB2, VAV1, CCL19, PIK3R2, CXCL1, GRK1, GNG2, GNAI2, CHUK, GNB3, CRKL, BCAR1, PIK3CD, GRK7, GNB2, STAT5B, HCK, GSK3A, IKBKG, CRK, GNB5, GRK6, PIK3R5, NFKBIB, GNG8, CCL4, PRKCD, NFKB1, ELMO1, ADCY8, CCL13, CCR5, CCR1, CCL3, CXCL8, CCL7, PRKCZ	1481	179	5892	2.933787000328179	2.0412871342089593E-40	2.916124477441371E-41	1.0262249046002336E-39
KEGG_PATHWAY	hsa04510:Focal adhesion	142	7.638515330823023	1.5663773262643232E-42	CCND1, PDGFD, ELK1, CAV2, MAPK10, COL4A1, ITGA3, ITGB8, PDPK1, RAC2, COL2A1, ITGB7, ACTN4, PDGFB, BCL2, BRAF, SHC2, PAK1, COL6A3, TLN1, ITGB1, BAD, COL4A2, ROCK1, SOS1, PDGFA, FLNB, PDGFC, LAMA5, ITGA1, SHC3, SHC4, RHOA, MAPK9, EGF, SOS2, CAV3, MYL7, MAPK8, COL4A3, CDC42, PRKCA, MAP2K1, PAK6, CTNNB1, ACTN2, ACTN1, MYL12A, AKT3, TNXB, ITGAV, ITGA2, AKT2, MAPK1, RAC3, FYN, MYL10, RAP1A, RAP1B, COL1A1, RASGRF1, MAPK3, RAF1, MYL5, PIK3CB, PTK2, PXN, PIK3CA, ACTG1, IBSP, EGFR, AKT1, ITGA5, IGF1, SRC, PDGFRA, PIK3CG, ACTB, SPP1, COL4A5, RELN, CAV1, PPP1CA, PIK3R1, GRB2, PIK3R3, PAK3, SHC1, PPP1CB, GSK3B, VAV2, FLNA, FLT1, PRKCB, ITGB3, COL1A2, RAC1, MYL12B, COL4A6, IGF1R, JUN, KDR, VAV1, ILK, VWF, VEGFA, PGF, PIK3R2, PTEN, VEGFC, THBS2, FN1, VEGFB, MYL2, CCND2, PPP1CC, MET, BIRC3, PARVB, BCAR1, CRKL, BIRC2, PIK3CD, HGF, ERBB2, LAMC1, CCND3, THBS1, CRK, PIK3R5, PAK4, PRKCG, MYLPF, PAK2, LAMA1, FLNC, VASP, MYLK, MYL9, TNR, DOCK1, VTN, ITGA6	1481	201	5892	2.810605984258317	4.07258104828724E-40	5.09072631035905E-41	2.0474258754268246E-39
KEGG_PATHWAY	hsa04915:Estrogen signaling pathway	87	4.679935449166218	3.73971431523893E-42	ITPR3, ADCY9, SRC, CREB3L4, PRKACG, PIK3CG, MMP9, PLCB3, ADCY1, ADCY2, PLCB4, CALML5, HSPA8, CALM3, PIK3R1, CREB3L1, CALML3, CREB3L3, GRB2, PIK3R3, CREB3, CREB5, ADCY5, PRKACA, GNAI1, MAP2K2, PRKACB, SHC1, SHC2, ADCY7, PLCB2, GNAS, ADCY4, SOS1, CREB1, GABBR2, JUN, HSP90AB1, ESR2, SHC3, SHC4, GABBR1, SOS2, PIK3R2, HSPA1L, PLCB1, MAP2K1, KCNJ9, ITPR1, GNAI2, AKT3, HSP90AA1, CALML6, PIK3CD, KCNJ6, HSP90B1, NOS3, AKT2, MAPK1, OPRM1, FOS, HSPA6, CREB3L2, GNAI3, ADCY3, PIK3R5, ATF4, GNAQ, ATF2, HSPA2, MAPK3, PRKCD, ADCY6, ADCY8, RAF1, ESR1, ATF6B, PIK3CB, GNAO1, MMP2, HSPA1A, PIK3CA, KRAS, EGFR, SP1, NRAS, AKT1	1481	95	5892	3.643370411173105	9.723257219621218E-40	1.0803619132912465E-40	4.8882141788818425E-39
KEGG_PATHWAY	hsa04728:Dopaminergic synapse	103	5.540613232920926	1.5005816576548312E-41	PPP2R2D, CREB3L4, PRKACG, MAPK12, MAPK10, GRIA2, GRIA3, PLCB4, PPP2R2C, CALML5, CALM3, CAMK2A, PRKACB, GNB4, GNG13, CLOCK, GRIA1, PPP2CA, CAMK2G, MAPK9, DRD2, CAMK2B, MAPK14, PPP2R5E, CAMK2D, MAPK8, PRKCA, PLCB1, CACNA1A, KCNJ9, ITPR1, AKT3, GNG12, AKT2, GNAL, FOS, CREB3L2, GNAI3, PPP2R5A, PPP2R3A, KIF5A, GNG7, PPP2R5B, GNG3, GNG5, GNAO1, GRIN2B, GNGT1, AKT1, ITPR3, PPP2R2A, PPP2CB, GNG4, GNG10, PPP2R1B, PPP2R1A, PPP3CA, PLCB3, GRIN2A, PPP1CA, CALML3, CREB3L1, CREB3L3, CREB3, PPP2R3C, CREB5, MAPK11, ADCY5, PPP2R2B, PRKACA, GNAI1, MAPK13, PLCB2, GNAS, PPP1CB, GSK3B, PRKCB, CREB1, PPP1CC, GNG2, GNAI2, PPP3CB, ARNTL, GNB3, CALML6, PPP2R5C, KCNJ6, PPP1R1B, GRIA4, GNB2, PPP2R5D, GSK3A, GNB5, ATF4, PPP3CC, PRKCG, GNAQ, CACNA1C, ATF2, GNG8, ATF6B, DRD3, DRD4	1481	124	5892	3.304632876652654	3.901512309902561E-39	3.901512309902561E-40	1.9614237658818924E-38
KEGG_PATHWAY	hsa05215:Prostate cancer	80	4.303388918773534	6.29354425102149E-40	CCND1, IGF1, TCF7, CCNE2, PDGFD, CREB3L4, PDGFRA, PIK3CG, ARAF, FOXO1, PIK3R1, CREB3L1, CREB3L3, GRB2, PIK3R3, PDPK1, MDM2, CREB3, CREB5, INS, CDKN1A, LEF1, MAP2K2, PDGFB, CASP9, BCL2, BRAF, TCF7L2, RB1, TCF7L1, E2F1, GSK3B, BAD, NFKBIA, CCNE1, SOS1, PDGFA, PDGFC, CREB1, TP53, IGF1R, HSP90AB1, RELA, EGF, SOS2, PIK3R2, PTEN, E2F3, CDKN1B, IKBKB, MAP2K1, CREBBP, CTNNB1, CHUK, AR, AKT3, HSP90AA1, PIK3CD, HSP90B1, ERBB2, AKT2, MAPK1, FGFR2, MTOR, IKBKG, CREB3L2, PIK3R5, EP300, ATF4, MAPK3, NKX3-1, NFKB1, CDK2, RAF1, PIK3CB, PIK3CA, KRAS, EGFR, NRAS, AKT1	1481	86	5892	3.700830676946752	1.6363215052655873E-37	1.4875650047868976E-38	8.226348231441853E-37
KEGG_PATHWAY	hsa04014:Ras signaling pathway	147	7.907477138246369	6.812716270376636E-40	RASSF5, TBK1, PDGFD, RRAS2, ELK1, PRKACG, FGF10, MAPK10, FGF2, CALML5, CALM3, RAC2, PLCG2, INS, INSR, MAP2K2, PRKACB, PDGFB, GNB4, ANGPT2, SHC2, PAK1, BAD, HTR7, GNG13, SOS1, PDGFA, PDGFC, BCL2L1, SHC3, SHC4, RHOA, RELA, MAPK9, EGF, SOS2, NGF, MAPK8, BRAP, CDC42, PRKCA, IKBKB, GRIN1, EFNA1, MAP2K1, PAK6, RAB5B, FGF1, AKT3, GNG12, ZAP70, AKT2, PTPN11, FGFR2, MAPK1, ETS2, RAC3, RAP1A, RAP1B, FGF13, PLCE1, FGFR3, ETS1, RASGRF1, PLCG1, MAPK3, PLA2G10, PLD2, ANGPT4, GNG7, GNG3, RAF1, CSF1, PIK3CB, GNG5, PIK3CA, RRAS, NF1, GRIN2B, KRAS, EGFR, GNGT1, AKT1, FGF12, NRAS, FGF3, IGF1, GNG4, GNG10, NGFR, PDGFRA, PIK3CG, GRIN2A, PIK3R1, CALML3, GRB2, PIK3R3, MRAS, PRKACA, PAK3, SHC1, ANGPT1, REL, FGF7, FGFR4, FLT1, PRKCB, ABL1, RAC1, FASLG, FGF18, IGF1R, PLD1, KDR, VEGFA, PGF, PIK3R2, VEGFC, PLA2G2A, KITLG, VEGFB, CSF1R, MET, GNG2, CHUK, CALML6, GNB3, PIK3CD, HGF, GNB2, FOXO4, IKBKG, GNB5, GAB2, PIK3R5, PAK4, PRKCG, GNG8, PAK2, NFKB1, RAB5C, KIT, GAB1, RAB5A, ARF6, EFNA4, EFNA5	1481	219	5892	2.6704281631256186	1.7713062302979254E-37	1.4760885252482712E-38	8.904962642160122E-37
KEGG_PATHWAY	hsa04015:Rap1 signaling pathway	139	7.477138246369015	8.37624754406972E-39	RASSF5, ADCY9, PDGFD, FGF10, MAPK12, ADCY2, ADCY1, PLCB4, PFN1, FGF2, CALML5, CALM3, RAC2, CTNND1, INS, INSR, MAP2K2, PDGFB, BRAF, ANGPT2, ADCY7, TLN1, ITGB1, ADCY4, PDGFA, PDGFC, RHOA, EGF, DRD2, MAPK14, NGF, CDC42, MAGI1, MAP2K6, PLCB1, PRKCA, GRIN1, EFNA1, MAP2K1, MAGI3, FGF1, CTNNB1, AKT3, LCP2, PRKCI, AKT2, FGFR2, MAPK1, RAC3, ITGAM, MAP2K3, RAP1A, RAP1B, FGF13, GNAI3, PLCE1, ADCY3, FGFR3, PLCG1, MAPK3, ANGPT4, ADCY6, RAF1, CSF1, DOCK4, PIK3CB, GNAO1, PIK3CA, ACTG1, RRAS, GRIN2B, KRAS, EGFR, CNR1, AKT1, FGF12, NRAS, RAPGEF6, FGF3, IGF1, SRC, NGFR, PDGFRA, PIK3CG, ACTB, PLCB3, GRIN2A, PIK3R1, CDH1, CALML3, PIK3R3, MRAS, MAPK11, ADCY5, GNAI1, MAPK13, ANGPT1, PLCB2, GNAS, RGS14, FGF7, FGFR4, FLT1, PRKCB, ITGB2, ITGB3, RAC1, IGF1R, FGF18, KDR, ITGAL, PRKD2, VEGFA, PGF, PIK3R2, F2R, VEGFC, KITLG, VEGFB, CSF1R, MET, ADORA2A, GNAI2, CALML6, BCAR1, CRKL, PIK3CD, HGF, THBS1, CRK, PIK3R5, PRKCG, GNAQ, KIT, ADCY8, VASP, EFNA4, EFNA5, PRKCZ	1481	204	5892	2.710767764229257	2.177824361458127E-36	1.6752495088139438E-37	1.0948668416702266E-35
KEGG_PATHWAY	hsa04114:Oocyte meiosis	88	4.733727810650888	5.126652180675718E-38	ITPR3, IGF1, ADCY9, PPP2CB, CDC16, ANAPC1, CCNE2, PPP2R1B, CDC20, PPP2R1A, PPP3CA, PRKACG, YWHAB, ADCY1, ADCY2, PPP1CA, CALML5, CALM3, PLK1, CALML3, ESPL1, CAMK2A, ADCY5, CUL1, CDC27, INS, PRKACA, PKMYT1, SMC3, PRKACB, PPP3R1, CDC25C, FBXW11, PGR, ANAPC10, ANAPC11, ADCY7, PPP1CB, CCNE1, ADCY4, IGF1R, RPS6KA1, YWHAE, PPP2CA, SMC1A, RPS6KA6, CAMK2G, CAMK2B, PPP2R5E, CAMK2D, ANAPC5, ANAPC4, MAD2L1, ANAPC2, PPP1CC, BTRC, PTTG1, RPS6KA2, MAP2K1, CDK1, PTTG2, ITPR1, YWHAG, PPP3CB, AR, PPP2R5C, CALML6, SKP1, RBX1, MAPK1, PPP2R5D, MAD2L2, MOS, CDC26, YWHAZ, SMC1B, PPP2R5A, ADCY3, PPP3R2, BUB1, RPS6KA3, PPP3CC, MAPK3, CDK2, PPP2R5B, ADCY6, ADCY8, YWHAH	1481	102	5892	3.4323390395996345	1.3329295669756867E-35	9.520925478397763E-37	6.701093122984575E-35
KEGG_PATHWAY	hsa05142:Chagas disease (American trypanosomiasis)	88	4.733727810650888	2.5062765897522304E-37	PPP2R2D, PPP2R2A, TGFBR1, PPP2CB, IRAK4, PPP2R1B, PPP2R1A, PIK3CG, TLR4, MAPK12, PLCB3, MAPK10, TICAM1, SMAD3, ADCY1, PLCB4, PPP2R2C, PIK3R1, PIK3R3, MAPK11, PPP2R2B, GNAI1, MAPK13, GNA11, CCL5, CFLAR, PLCB2, GNAS, CASP8, CCL2, NFKBIA, TLR9, FASLG, TNFRSF1A, JUN, TGFBR2, PPP2CA, RELA, MAPK9, MAP2K4, PIK3R2, TLR2, MAPK14, CD3E, TGFB1, MAPK8, IL1B, CD247, MYD88, PLCB1, IKBKB, GNA15, CALR, TNF, NOS2, TGFB2, IL6, GNAI2, CHUK, AKT3, PIK3CD, IRAK1, AKT2, FADD, IL10, MAPK1, GNAL, FOS, IL12A, TRAF6, IKBKG, GNAI3, IFNG, PIK3R5, IFNB1, GNAQ, MAPK3, NFKB1, BDKRB2, IL2, SMAD2, PIK3CB, GNAO1, PIK3CA, FAS, CCL3, CXCL8, AKT1	1481	103	5892	3.399015359603522	6.516319133355799E-35	4.3442127555705326E-36	3.2759766467465453E-34
KEGG_PATHWAY	hsa04914:Progesterone-mediated oocyte maturation	76	4.088219472834857	7.270997047122295E-36	CCNB2, IGF1, ADCY9, CDC16, ANAPC1, PRKACG, PIK3CG, MAPK12, ARAF, MAPK10, ADCY1, ADCY2, PLK1, PIK3R1, PIK3R3, MAPK11, ADCY5, CDC27, CDC25A, INS, PRKACA, PKMYT1, GNAI1, PRKACB, CDC25C, MAPK13, BRAF, PGR, ANAPC10, ANAPC11, ADCY7, FZR1, ADCY4, CCNA2, IGF1R, RPS6KA1, CCNB1, HSP90AB1, RPS6KA6, MAPK9, MAPK14, PIK3R2, MAPK8, ANAPC5, MAD2L1, ANAPC4, ANAPC2, RPS6KA2, MAP2K1, CDK1, GNAI2, AKT3, HSP90AA1, PIK3CD, AKT2, MAPK1, MAD2L2, MOS, CDC26, GNAI3, ADCY3, MAD1L1, PIK3R5, BUB1, RPS6KA3, CCNA1, MAPK3, CDK2, ADCY6, ADCY8, RAF1, PDE3B, PIK3CB, PIK3CA, KRAS, AKT1	1481	84	5892	3.599498408411305	1.8904592322517967E-33	1.181537020157373E-34	9.50398556261922E-33
KEGG_PATHWAY	hsa04380:Osteoclast differentiation	99	5.325443786982249	5.667186546112994E-35	JUNB, MAP3K14, TNFRSF11A, TNFSF11, MAPK12, MAPK10, SOCS1, NFATC2, MAP3K7, IL1R1, PLCG2, SIRPA, NFKBIA, BLNK, RELB, STAT2, MAPK9, RELA, MAPK14, TAB2, TGFB1, IL1B, MAPK8, LCK, MAP2K6, IKBKB, MAP2K1, NCF1, TGFB2, AKT3, LCP2, NFATC1, SYK, AKT2, MAPK1, FYN, PPARG, FOS, SQSTM1, MAPK3, TRAF2, CSF1, NCF4, PIK3CB, PIK3CA, IFNAR2, TYROBP, MAP2K7, AKT1, TGFBR1, LILRB4, STAT1, PIK3CG, PPP3CA, BTK, FHL2, PIK3R1, PIK3R3, GRB2, MAPK11, MAPK13, PPP3R1, IFNAR1, SPI1, ITGB3, CREB1, RAC1, TNFRSF1A, FOSL2, JUN, TGFBR2, PIK3R2, FOSB, SOCS3, FOSL1, CSF1R, TNF, MITF, PPP3CB, CHUK, TEC, PIK3CD, NFKB2, JUND, TRAF6, IKBKG, IFNG, GAB2, JAK1, PPP3R2, PIK3R5, PPP3CC, IFNB1, TAB1, NFKB1, CAMK4, TYK2, IL1A, CYLD	1481	128	5892	3.077038318703579	1.4734685019893783E-32	8.667461776408109E-34	7.407630448185197E-32
KEGG_PATHWAY	hsa04010:MAPK signaling pathway	154	8.284023668639055	7.241825527865061E-35	ELK1, RRAS2, MAP3K14, PRKACG, MAPK12, DUSP1, FGF10, MAPK10, FGF2, MAP3K7, HSPA8, IL1R1, MAP3K5, RAC2, MAP2K2, PRKACB, PDGFB, BRAF, MAPKAPK2, DUSP3, PAK1, MAP3K4, PDGFA, SOS1, FLNB, PPP5C, RELB, MAPK9, RELA, MAP2K4, EGF, SOS2, MAPK14, TAB2, ARRB1, TGFB1, NGF, MAPK8, IL1B, HSPA1L, CDC42, MAP2K6, PRKCA, IKBKB, MAP3K12, IL1R2, MAP2K1, CACNA1A, TGFB2, FGF1, GNG12, AKT3, NFATC1, AKT2, MAPK1, FGFR2, RAC3, MOS, MYC, SRF, FOS, MAP2K3, HSPA6, RAP1B, RAP1A, RPS6KA4, MAPT, FGF13, MAP3K1, FGFR3, MAP4K1, RASGRF1, MAPK3, TRAF2, RAF1, MEF2C, MAP3K2, RRAS, FAS, NF1, KRAS, RPS6KA5, EGFR, MAP2K7, AKT1, NRAS, FGF12, BDNF, TGFBR1, FGF3, GADD45B, PDGFRA, PPP3CA, STK3, GRB2, MAPK8IP2, MAPK11, MRAS, PRKACA, PPP3R1, ELK4, MAPK13, ECSIT, FGFR4, FGF7, FLNA, PRKCB, MAP3K11, RAC1, TNFRSF1A, FASLG, TP53, FGF18, RPS6KA1, JUN, TGFBR2, ARRB2, STMN1, RPS6KA6, DDIT3, HSPB1, RPS6KA2, TNF, MAPK7, MAP2K5, PPP3CB, CHUK, CRKL, NFKB2, NTRK1, JUND, NFATC3, MAPKAPK5, NR4A1, TRAF6, CRK, IKBKG, MAP3K8, PPP3R2, ATF4, RPS6KA3, PPP3CC, PRKCG, HSPA2, ATF2, CACNA1C, PAK2, NFKB1, TAB1, FLNC, HSPA1A, IL1A, CASP3, MAP3K3	1481	251	5892	2.4409263687989435	1.8828746372449159E-32	1.0460414651360644E-33	9.46585520772241E-32
KEGG_PATHWAY	hsa04660:T cell receptor signaling pathway	84	4.518558364712211	1.6708473775902604E-34	MAP3K14, PPP3CA, PIK3CG, MAPK12, NFATC2, MAP3K7, PIK3R1, PTPN6, GRB2, PIK3R3, PDPK1, MAPK11, PAK3, MAP2K2, PPP3R1, MAPK13, PAK1, PTPRC, GSK3B, CBLB, NFKBIA, VAV2, SOS1, IL5, ITK, JUN, VAV1, RHOA, RELA, SOS2, PIK3R2, MAPK14, CD3E, DLG1, CD247, LCK, CDC42, BCL10, CBL, CD4, IKBKB, TNF, MAP2K1, PAK6, MALT1, PPP3CB, CHUK, TEC, AKT3, LCP2, PIK3CD, ZAP70, NFATC1, AKT2, IL10, MAPK1, FYN, NFATC3, FOS, IKBKG, NFKBIE, MAP3K8, IFNG, PPP3R2, PIK3R5, NFKBIB, PAK4, PPP3CC, PLCG1, MAPK3, PAK2, NFKB1, RAF1, IL2, PRKCQ, CBLC, PIK3CB, CDK4, PIK3CA, KRAS, NCK1, MAP2K7, NRAS, AKT1	1481	100	5892	3.3418501012829167	4.344203181734677E-32	2.2864227272287773E-33	2.183979618069418E-31
KEGG_PATHWAY	hsa05220:Chronic myeloid leukemia	67	3.604088219472835	2.6939631702205226E-34	CCND1, TGFBR1, HDAC2, PIK3CG, CDKN2A, ARAF, STAT5A, PIK3R1, BCR, GRB2, PIK3R3, MDM2, CDK6, CDKN1A, MAP2K2, SHC1, BRAF, RB1, SHC2, E2F1, BAD, CBLB, NFKBIA, RUNX1, ABL1, SOS1, TP53, BCL2L1, TGFBR2, SHC3, SHC4, RELA, SOS2, PIK3R2, TGFB1, E2F3, CDKN1B, CBL, IKBKB, MAP2K1, TGFB2, CHUK, HDAC1, AKT3, CRKL, CTBP1, PIK3CD, STAT5B, AKT2, PTPN11, MAPK1, MYC, CRK, IKBKG, GAB2, PIK3R5, MAPK3, NFKB1, RAF1, CBLC, PIK3CB, SMAD4, CDK4, PIK3CA, KRAS, NRAS, AKT1	1481	71	5892	3.7542581620716873	7.004304242573359E-32	3.5021521212866795E-33	3.52130346224484E-31
KEGG_PATHWAY	hsa05162:Measles	99	5.325443786982249	5.536839488793096E-34	CCND1, TBK1, IRAK4, TLR4, MAP3K7, HSPA8, NFKBIA, CCNE1, MAVS, TLR9, IL2RB, STAT2, DDX58, RELA, IL2RA, TLR2, TAB2, CDKN1B, IL1B, IFNA8, MYD88, HSPA1L, BBC3, IKBKE, IL6, IRF7, AKT3, JAK2, AKT2, FYN, IL12A, HSPA6, EIF2AK2, CDK2, IRF3, IL2, PIK3CB, CDK4, PIK3CA, FAS, IFNAR2, EIF2S1, TP73, AKT1, STAT3, IL2RG, STAT1, CCNE2, PIK3CG, STAT5A, JAK3, PIK3R1, PIK3R3, EIF2AK1, EIF2AK4, CDK6, IFIH1, GSK3B, MSN, IFNAR1, CD209, TP53, FASLG, PIK3R2, IFNA4, IFNA16, CD3E, IFNA6, IFNA10, CSNK2A2, TNFRSF10B, IFNA21, IFNA5, CCND2, IFNA1, CSNK2B, CSNK2A1, CHUK, PIK3CD, IRAK1, STAT5B, IFNA14, IFNA17, CCND3, TRAF6, TNFRSF10A, IFNG, JAK1, PIK3R5, NFKBIB, IFNB1, HSPA2, NFKB1, PRKCQ, EIF2AK3, TYK2, HSPA1A, IL1A, CLEC4M	1481	130	5892	3.029699267646601	1.439578267086205E-31	6.855134605172405E-33	7.237252638529985E-31
KEGG_PATHWAY	hsa04024:cAMP signaling pathway	127	6.831629908552986	2.1028305975130066E-33	ADCY9, RRAS2, PDE4A, CREB3L4, PRKACG, MAPK10, GRIA2, GRIA3, HTR1E, ADCY1, ADCY2, CALML5, CALM3, NPY, GRIN2D, RAC2, CAMK2A, CHRM2, MAP2K2, PRKACB, BRAF, ADCY7, PAK1, ATP2B4, BAD, NFKBIA, ROCK1, ADCY4, RYR2, GRIA1, GABBR2, RHOA, RELA, CAMK2G, MAPK9, DRD2, CAMK2B, CAMK2D, MAPK8, GRIN1, CREBBP, MAP2K1, AKT3, CFTR, ATP1A2, NFATC1, AKT2, MAPK1, RAC3, GLI1, FOS, CREB3L2, RAP1A, RAP1B, HTR1D, GNAI3, ADCY3, PLCE1, GLI3, PLN, HTR1B, MAPK3, PLD2, ADCY6, RAF1, ADRB2, PIK3CB, PDE4B, PIK3CA, FSHR, RRAS, GRIN2B, AKT1, BDNF, PIK3CG, GRIN2A, PPP1CA, PIK3R1, ADCYAP1R1, CALML3, CREB3L1, CREB3L3, PIK3R3, CREB3, CREB5, FXYD2, ADCY5, PRKACA, GNAI1, PPARA, ATP1A1, ATP1B1, GNAS, PPP1CB, ORAI1, VAV2, CREB1, RAC1, JUN, PLD1, VAV1, GABBR1, PIK3R2, F2R, PPP1CC, ADRB1, ADORA2A, GNAI2, NPR1, CALML6, PIK3CD, GRIA4, PPP1R1B, HTR1F, FSHB, PIK3R5, EP300, CACNA1C, SLC9A1, NFKB1, CAMK4, ADCY8, TSHR, HTR1A, MYL9, PDE3B, ATP1A3	1481	192	5892	2.631541188386226	5.467359553533817E-31	2.4851634334244623E-32	2.7486287657491625E-30
KEGG_PATHWAY	hsa05169:Epstein-Barr virus infection	122	6.56266810112964	2.7670131338894263E-33	TBK1, MAP3K14, SNW1, PRKACG, MAPK12, MAPK10, MAP3K7, HSPA8, RBPJL, MDM2, PLCG2, CDKN1A, PRKACB, BCL2, RB1, NFKBIA, CCNA2, USP7, RELB, HDAC5, YWHAE, DDX58, RELA, MAPK9, MAP2K4, MAPK14, TAB2, CDKN1B, MAPK8, PSMC2, GTF2B, HSPA1L, MAP2K6, IKBKB, CREBBP, TRAF5, AKT3, AKT2, SYK, IL10, PSMC3, MYC, MAP2K3, TRAF3, HSPA6, LYN, YWHAZ, CD40, NCOR2, TBP, EIF2AK2, CCNA1, PLCG1, TBPL1, CDK2, TRAF2, IRF3, PIK3CB, PIK3CA, YWHAH, MAP2K7, STAT3, AKT1, PSMD3, HDAC2, PTMA, PIK3CG, YWHAB, JAK3, PIK3R1, PIK3R3, EIF2AK1, MAPK11, EIF2AK4, RAN, PRKACA, HLA-A, HLA-E, MAPK13, GSK3B, SPI1, TP53, HLA-G, JUN, ITGAL, TRADD, PSMD7, PIK3R2, HSPB1, CSNK2A2, CSNK2B, CDK1, CSNK2A1, HLA-B, YWHAG, CHUK, HDAC1, RIPK1, PIK3CD, NFKB2, VIM, IRAK1, IL10RB, TRAF6, IKBKG, NFKBIE, IFNG, JAK1, HLA-F, PIK3R5, EP300, NFKBIB, HSPA2, ATF2, TAB1, NFKB1, PSMD13, EIF2AK3, TYK2, HSPA1A, XPO1, CD44	1481	181	5892	2.6815687474119696	7.194234148112509E-31	3.1279278904836995E-32	3.6167877260342054E-30
KEGG_PATHWAY	hsa04620:Toll-like receptor signaling pathway	84	4.518558364712211	2.89780418123436E-33	TBK1, STAT1, IRAK4, PIK3CG, TLR4, MAPK12, MAPK10, TICAM1, SPP1, MAP3K7, PIK3R1, PIK3R3, MAPK11, TICAM2, TOLLIP, MAP2K2, IRF5, MAPK13, CCL5, CASP8, NFKBIA, IFNAR1, TLR9, RAC1, JUN, TIRAP, RELA, MAPK9, MAP2K4, PIK3R2, MAPK14, TLR2, TAB2, IFNA4, TLR1, IFNA16, IFNA6, MAPK8, IL1B, IFNA8, IFNA10, MYD88, IFNA21, IFNA5, IFNA1, MAP2K6, IKBKB, TNF, MAP2K1, IKBKE, IRF7, IL6, CHUK, RIPK1, AKT3, PIK3CD, IRAK1, AKT2, FADD, MAPK1, IFNA14, IFNA17, FOS, IL12A, TRAF6, IKBKG, MAP2K3, TRAF3, MAP3K8, PIK3R5, CD40, IFNB1, CCL4, MAPK3, TAB1, NFKB1, IRF3, PIK3CB, PIK3CA, IFNAR2, CCL3, MAP2K7, CXCL8, AKT1	1481	102	5892	3.276323628708742	7.534290871209336E-31	3.13928786300389E-32	3.787745879039929E-30
KEGG_PATHWAY	hsa04668:TNF signaling pathway	86	4.626143087681549	3.8612551619855226E-33	JUNB, MAP3K14, CREB3L4, PIK3CG, MMP9, MAPK12, SELE, MAPK10, MAP3K7, PIK3R1, CREB3L1, CREB3L3, PIK3R3, MAP3K5, CREB3, CREB5, MAPK11, MMP14, CASP7, ITCH, MAPK13, CCL5, CFLAR, CASP8, CCL2, PTGS2, NFKBIA, CREB1, TNFRSF1A, JUN, TRADD, RELA, MAPK9, MAP2K4, PIK3R2, MAPK14, TAB2, SOCS3, MAPK8, IL1B, CXCL1, MAP2K6, IKBKB, TNF, BIRC3, MAP2K1, IL6, TRAF5, CHUK, AKT3, RIPK1, BIRC2, PIK3CD, AKT2, FADD, DNM1L, MAPK1, CXCL2, FOS, IKBKG, MAP2K3, TRAF3, CREB3L2, RPS6KA4, MAP3K8, VCAM1, PIK3R5, ATF4, ATF2, MAPK3, TAB1, NFKB1, TRAF2, CASP10, CSF1, ATF6B, PIK3CB, MMP3, PIK3CA, FAS, CEBPB, CASP3, RPS6KA5, TNFRSF1B, MAP2K7, AKT1	1481	106	5892	3.2277527932427095	1.0039263421162359E-30	4.0157053684649437E-32	5.0470813115820685E-30
KEGG_PATHWAY	hsa05164:Influenza A	113	6.078536847767617	3.747511879713114E-32	TBK1, IRAK4, TLR4, MAPK12, MAPK10, FDPS, HSPA8, HLA-DMB, MAP2K2, CASP9, CCL5, CCL2, NFKBIA, NLRP3, MAVS, HLA-DRA, STAT2, DDX58, RELA, MAPK9, MAP2K4, MAPK14, IL1B, MAPK8, IFNA8, CASP1, MYD88, HSPA1L, MAP2K6, IKBKB, PRKCA, CREBBP, MAP2K1, IKBKE, IL6, IRF7, AKT3, JAK2, AKT2, MAPK1, IL12A, MAP2K3, DNAJC3, HSPA6, EIF2AK2, MAPK3, IRF3, CYCS, RAF1, PIK3CB, PIK3CA, ACTG1, FAS, IFNAR2, EIF2S1, MAP2K7, AKT1, STAT1, ACTB, PIK3CG, TICAM1, PIK3R1, PIK3R3, EIF2AK1, MAPK11, EIF2AK4, IFIH1, MAPK13, GSK3B, IFNAR1, PRKCB, FASLG, TNFRSF1A, HLA-DPB1, JUN, PIK3R2, IFNA4, IFNA16, SOCS3, IFNA6, IFNA10, TNFRSF10B, IFNA21, IFNA5, IFNA1, TNF, DNAJB1, RSAD2, PIK3CD, KPNA2, IFNA14, IFNA17, TNFRSF10A, PABPN1, IFNG, CIITA, JAK1, PIK3R5, EP300, NFKBIB, IFNB1, ATF2, HSPA2, HLA-DRB1, NFKB1, NUP98, EIF2AK3, TYK2, HSPA1A, XPO1, IL1A, CXCL8, PML	1481	164	5892	2.741209795622602	9.743530887254096E-30	3.7475118797131137E-31	4.8984064454590325E-29
KEGG_PATHWAY	hsa04713:Circadian entrainment	77	4.142011834319527	4.974047173284903E-32	RASD1, ITPR3, ADCY9, PRKG2, GNG4, GNG10, PRKACG, NOS1AP, PLCB3, GRIA2, GRIA3, GRIN2A, ADCY1, ADCY2, PLCB4, CALML5, ADCYAP1R1, CALM3, CALML3, GRIN2D, CAMK2A, ADCY5, PRKACA, GNAI1, PRKACB, PER3, GNB4, ADCY7, PLCB2, GNAS, ADCY4, GNG13, PRKCB, RYR2, CREB1, GRIA1, CAMK2G, CAMK2B, CAMK2D, PRKCA, PLCB1, GRIN1, KCNJ9, MTNR1B, ITPR1, GNG2, GNAI2, GNG12, CALML6, PER2, GNB3, KCNJ6, GRIA4, GNB2, NOS1, MAPK1, FOS, GNAI3, GNB5, ADCY3, PRKCG, GNG8, CACNA1C, GNAQ, MTNR1A, MAPK3, PRKG1, GNG7, PER1, ADCY6, ADCY8, GNG3, GNG5, GNAO1, GRIN2B, RPS6KA5, GNGT1	1481	91	5892	3.3663325196073344	1.2932522650540748E-29	4.789823203903981E-31	6.501621746827198E-29
KEGG_PATHWAY	hsa04910:Insulin signaling pathway	98	5.27165142549758	1.2268939981854398E-31	PHKB, ELK1, TSC2, PRKACG, RPS6, MAPK10, ARAF, SOCS1, CALML5, CALM3, RHOQ, SOCS4, PDPK1, IRS4, INS, PPP1R3A, INSR, MAP2K2, PRKACB, BRAF, SHC2, BAD, PPP1R3E, SOS1, SHC3, SHC4, MAPK9, SOS2, SOCS2, MAPK8, CBL, IKBKB, MAP2K1, PRKAR2A, PRKAR1A, AKT3, PRKCI, PTPRF, PYGM, AKT2, MAPK1, PYGB, MTOR, GYS2, PRKAA1, FASN, MAPK3, PTPN1, IRS2, RAF1, PIK3CB, PIK3CA, KRAS, NRAS, AKT1, PHKA2, PIK3CG, PYGL, FOXO1, IRS1, INPPL1, PPP1CA, PIK3R1, CALML3, SREBF1, PIK3R3, GRB2, PPP1R3F, RHEB, PRKACA, GYS1, SHC1, PPP1CB, GSK3B, CBLB, TSC1, PIK3R2, SOCS3, PPP1CC, RPS6KB1, TRIP10, PPP1R3B, PPP1R3C, CRKL, CALML6, PIK3CD, CRK, PIK3R5, PPP1R3D, EIF4EBP1, PCK1, EIF4E, SLC2A4, PHKG1, CBLC, PDE3B, PHKG2, PRKCZ	1481	133	5892	2.9314474572657168	3.1899243952821435E-29	1.1392587126007656E-30	1.6036841673912545E-28
KEGG_PATHWAY	hsa04012:ErbB signaling pathway	73	3.9268423883808503	3.385365326884561E-31	SRC, ELK1, PIK3CG, ARAF, MAPK10, STAT5A, PIK3R1, GRB2, PIK3R3, PLCG2, CAMK2A, CDKN1A, PAK3, MAP2K2, SHC1, BRAF, SHC2, PAK1, GSK3B, BAD, CBLB, ABL1, PRKCB, SOS1, JUN, SHC3, SHC4, MAPK9, CAMK2G, MAP2K4, EGF, SOS2, PIK3R2, CAMK2B, CAMK2D, CDKN1B, MAPK8, RPS6KB1, CBL, PRKCA, MAP2K1, PAK6, ERBB4, AKT3, CRKL, PIK3CD, STAT5B, ERBB2, AKT2, MAPK1, MYC, MTOR, CRK, PIK3R5, PAK4, PRKCG, PLCG1, EIF4EBP1, MAPK3, PAK2, GAB1, RAF1, CBLC, PTK2, PIK3CB, PIK3CA, ERBB3, KRAS, NCK1, EGFR, MAP2K7, NRAS, AKT1	1481	85	5892	3.416737498510545	8.801949849899859E-29	3.0351551206551236E-30	4.425041432747731E-28
KEGG_PATHWAY	hsa05214:Glioma	59	3.1737493275954813	1.2352629470926597E-30	CCND1, IGF1, PDGFRA, PIK3CG, CDKN2A, ARAF, CALML5, CALM3, PIK3R1, CALML3, GRB2, PIK3R3, MDM2, PLCG2, CAMK2A, CDK6, CDKN1A, MAP2K2, PDGFB, SHC1, BRAF, RB1, E2F1, SHC2, PRKCB, PDGFA, SOS1, TP53, IGF1R, SHC3, SHC4, CAMK2G, EGF, SOS2, PTEN, CAMK2B, PIK3R2, E2F3, CAMK2D, PRKCA, MAP2K1, AKT3, CALML6, PIK3CD, AKT2, MAPK1, MTOR, PIK3R5, PRKCG, PLCG1, MAPK3, RAF1, PIK3CB, CDK4, PIK3CA, KRAS, EGFR, NRAS, AKT1	1481	62	5892	3.785890091699157	3.2116836624409154E-28	1.0705612208136384E-29	1.6146232956941601E-27
KEGG_PATHWAY	hsa05203:Viral carcinogenesis	119	6.401291016675632	1.4197911725322952E-30	CCND1, CREB3L4, SNW1, CDC20, PRKACG, CDKN2A, CDKN2B, RBPJL, MDM2, CDKN1A, ACTN4, HNRNPK, PRKACB, MAPKAPK2, RB1, HDAC7, BAD, CASP8, NFKBIA, CCNE1, CCNA2, USP7, GTF2H1, BAX, HDAC5, YWHAE, RHOA, RELA, CDKN1B, GTF2B, CDC42, CREBBP, IRF7, TRAF5, ACTN2, ACTN1, SYK, MAPK1, RBL1, SRF, PMAIP1, TRAF3, CREB3L2, LYN, YWHAZ, TBP, EIF2AK2, CCNA1, TBPL1, MAPK3, CDK2, TRAF2, IRF3, GSN, PXN, PIK3CB, CDK4, PIK3CA, IL6ST, YWHAH, KRAS, STAT3, NRAS, SRC, CCNE2, HDAC2, PIK3CG, YWHAB, STAT5A, JAK3, PIK3R1, CREB3L1, CREB3L3, GRB2, PIK3R3, CREB3, CREB5, CDK6, CCR3, PRKACA, HLA-A, HLA-E, REL, CHEK1, POLB, CREB1, RAC1, TP53, HLA-G, JUN, HDAC8, TRADD, PIK3R2, VDAC3, DLG1, CCND2, HDAC3, CDK1, HLA-B, YWHAG, HDAC1, PIK3CD, NFKB2, STAT5B, CCND3, IKBKG, JAK1, MAD1L1, HLA-F, PIK3R5, EP300, ATF4, ATF2, EGR2, NFKB1, BAK1, ATF6B, CCR5, CASP3	1481	182	5892	2.6012569469693037	3.6914570485839676E-28	1.1907925963174088E-29	1.8558217969599716E-27
KEGG_PATHWAY	hsa05206:MicroRNAs in cancer	99	5.325443786982249	2.1261940628220534E-30	CCND1, CDKN2A, MMP9, SOCS1, MDM2, PLCG2, APC, CDKN1A, MAP2K2, HNRNPK, PDGFB, BCL2, BCL2L11, E2F1, PTGS2, ROCK1, CCNE1, MCL1, SOS1, PDGFA, EZH2, SHC4, RHOA, SOS2, CDKN1B, E2F3, MDM4, IKBKB, PRKCA, CREBBP, MAP2K1, TGFB2, ATM, TNXB, NOTCH1, MYC, MTOR, NOTCH3, UBE2I, WNT3A, FGFR3, PLCG1, IRS2, RAF1, RDX, RPS6KA5, KRAS, EGFR, NRAS, STAT3, PIM1, ITGA5, CCNE2, DDIT4, PDGFRA, IRS1, PRKCE, NOTCH2, EZR, GRB2, CDC25A, CDK6, TIMP3, CDC25C, SHC1, ABL1, PRKCB, ITGB3, DNMT3B, TP53, STMN1, NOTCH4, VEGFA, PTEN, PLAU, ZEB1, CCND2, DNMT3A, MET, MAPK7, CRKL, BRCA1, ERBB2, VIM, MARCKS, BMPR2, THBS1, CRK, EP300, PAK4, PRKCG, NFKB1, BAK1, ABCB1, TNR, ERBB3, CASP3, CCNG1, CD44	1481	138	5892	2.8540645274931746	5.528104563337339E-28	1.7275326760429183E-29	2.7791673611509885E-27
KEGG_PATHWAY	hsa05152:Tuberculosis	113	6.078536847767617	2.4736125144448006E-30	IRAK4, TLR4, MAPK12, MAPK10, CALML5, MRC1, CALM3, CAMK2A, HLA-DMB, CASP9, CTSS, RFXANK, BCL2, BAD, CASP8, IRAK2, TLR9, HLA-DRA, CD74, TIRAP, BAX, RHOA, RELA, CAMK2G, MAPK9, BID, TLR2, CAMK2B, MAPK14, TGFB1, CAMK2D, IL1B, MAPK8, IFNA8, MYD88, CREBBP, NOS2, IL6, TGFB2, MALT1, RAB5B, ARHGEF12, AKT3, JAK2, SYK, PLA2R1, AKT2, IL10, MAPK1, ITGAM, IL12A, MAPK3, CEBPG, CYCS, RAF1, CEBPB, AKT1, STAT1, SRC, PPP3CA, CALML3, MAPK11, PPP3R1, MAPK13, CD209, ITGB2, HSPA9, CREB1, TNFRSF1A, HLA-DPB1, HSPD1, PIK3C3, TRADD, TLR1, IFNA4, IFNA16, IFNA6, IFNA10, IFNA21, IFNA5, IFNA1, BCL10, TNF, PPP3CB, ATP6V0A1, CALML6, IRAK1, FADD, IFNA14, IL10RB, IFNA17, TRAF6, RFX5, IFNG, CIITA, PPP3R2, JAK1, EP300, PPP3CC, IFNB1, VDR, RIPK2, HLA-DRB1, NFKB1, RAB7A, NFYB, CASP10, RAB5C, RAB5A, IL1A, CASP3, CLEC4M, NFYA	1481	169	5892	2.660108914095306	6.431392537556481E-28	1.94890682956257E-29	3.233281140459552E-27
KEGG_PATHWAY	hsa05221:Acute myeloid leukemia	54	2.9047875201721354	6.620414444716502E-30	CCND1, TCF7, PIK3CG, ARAF, STAT5A, PIK3R1, PIK3R3, GRB2, RUNX1T1, LEF1, MAP2K2, CEBPA, BRAF, TCF7L2, TCF7L1, BAD, RUNX1, SPI1, SOS1, RELA, SOS2, PIM2, PIK3R2, RPS6KB1, IKBKB, MAP2K1, CHUK, AKT3, RARA, PIK3CD, STAT5B, AKT2, MAPK1, MYC, MTOR, IKBKG, FLT3, PIK3R5, PPARD, EIF4EBP1, MAPK3, JUP, NFKB1, KIT, RAF1, PIK3CB, PIK3CA, ZBTB16, KRAS, NRAS, AKT1, STAT3, PML, PIM1	1481	55	5892	3.906058559941072	1.7213077556262905E-27	5.06266986948909E-29	8.653603198208406E-27
KEGG_PATHWAY	hsa04630:Jak-STAT signaling pathway	100	5.3792361484669176	2.941290505123913E-29	CCND1, CSF2RB, SOCS1, SOCS7, SOCS4, IL4R, PIAS4, SOS1, CISH, LIFR, BCL2L1, IL12RB1, IL2RB, STAT2, IL3RA, IL2RA, SOS2, SOCS2, IFNA8, IL9R, CNTFR, IL21R, IL21, CREBBP, IL6, AKT3, JAK2, IL12RB2, STAM2, PTPN11, AKT2, IL10, MYC, IL12A, STAM, CRLF2, IL13RA1, IL2, OSMR, PIK3CB, PIK3CA, STAT4, IFNAR2, IL6ST, AKT1, STAT3, PIM1, IL2RG, STAT1, IL22RA2, IL13RA2, IL11, PIK3CG, STAT6, SOCS5, STAT5A, JAK3, PIK3R1, PTPN6, PIK3R3, GRB2, PIAS3, CSF3R, CSH2, PIAS2, IFNAR1, IL5, IFNLR1, IL5RA, IFNL1, PIK3R2, IFNA4, IFNA16, PIAS1, SOCS3, IFNA6, IFNA10, PRL, IFNA21, IFNA5, IFNA1, CCND2, GHR, IL7R, PIK3CD, STAT5B, IFNA14, IL15RA, IL10RB, IFNA17, CCND3, IFNG, JAK1, EP300, PIK3R5, IFNB1, IFNL3, PRLR, EPOR, TYK2	1481	143	5892	2.78209299141102	7.647355313322173E-27	2.1849586609491928E-28	3.8445872436752324E-26
KEGG_PATHWAY	hsa05168:Herpes simplex infection	114	6.132329209252286	4.530361101215087E-29	TBK1, EEF1D, MAPK10, MAP3K7, HLA-DMB, HNRNPK, PER3, SRPK1, CCL5, CASP8, CCL2, NFKBIA, USP7, CLOCK, MAVS, TLR9, MCRS1, HLA-DRA, CD74, STAT2, DDX58, RELA, MAPK9, TLR2, TAB2, IL1B, MAPK8, IFNA8, MYD88, IKBKB, CREBBP, IKBKE, IL6, IRF7, TRAF5, JAK2, SKP1, PTPN11, FOS, IL12A, TRAF3, TBP, EIF2AK2, TBPL1, CDK2, TRAF2, PER1, IRF3, CYCS, FAS, IFNAR2, EIF2S1, SRSF2, STAT1, C1QBP, TICAM1, PPP1CA, EIF2AK1, EIF2AK4, CUL1, SRSF9, HLA-A, HLA-E, IFIH1, TAF6, PPP1CB, IFNAR1, TP53, FASLG, TNFRSF1A, HMGN1, HLA-G, HLA-DPB1, JUN, IFNA4, IFNA16, SOCS3, IFNA6, IFNA10, CSNK2A2, IFNA21, IFNA5, PPP1CC, IFNA1, TNF, CSNK2B, CDK1, TAP1, CSNK2A1, HLA-B, HCFC1, CHUK, TAF10, ARNTL, PER2, FADD, IFNA14, IFNA17, TRAF6, IKBKG, IFNG, JAK1, EP300, HLA-F, NFKBIB, IFNB1, HLA-DRB1, TAB1, NFKB1, MED8, EIF2AK3, TYK2, CASP3, PML	1481	175	5892	2.59163885405614	1.1778938863159226E-26	3.271927461988674E-28	5.921675695968097E-26
KEGG_PATHWAY	hsa04912:GnRH signaling pathway	72	3.8730500268961805	9.719462907642192E-29	ITPR3, ADCY9, SRC, ELK1, PTK2B, PRKACG, MAPK12, PLCB3, MAPK10, ADCY1, ADCY2, PLCB4, CALML5, CALM3, CALML3, GRB2, CAMK2A, MAPK11, ADCY5, PRKACA, MAP2K2, MMP14, PRKACB, MAPK13, GNA11, ADCY7, PLCB2, GNAS, MAP3K4, ADCY4, PRKCB, SOS1, JUN, PLD1, MAPK9, CAMK2G, MAP2K4, SOS2, CGA, CAMK2B, MAPK14, CAMK2D, MAPK8, CDC42, MAP2K6, PLCB1, PRKCA, MAP2K1, MAPK7, ITPR1, CALML6, MAPK1, MAP2K3, ADCY3, FSHB, ATF4, MAP3K1, GNAQ, CACNA1C, MAPK3, PRKCD, PLD2, ADCY6, ADCY8, RAF1, MAP3K2, MMP2, KRAS, MAP2K7, EGFR, MAP3K3, NRAS	1481	87	5892	3.292463153973317	2.5270603559869698E-26	6.829892854018837E-28	1.270439728581707E-25
KEGG_PATHWAY	hsa05160:Hepatitis C	93	5.002689618074233	2.100081699748033E-28	EIF3E, PPP2R2D, PPP2R2A, TBK1, STAT1, PPP2CB, LDLR, PPP2R1B, PPP2R1A, PIK3CG, MAPK12, ARAF, MAPK10, TICAM1, PPP2R2C, PIK3R1, GRB2, PIK3R3, PDPK1, EIF2AK1, EIF2AK4, MAPK11, PPP2R2B, CDKN1A, PPARA, MAPK13, BRAF, GSK3B, BAD, NFKBIA, IFNAR1, SOS1, MAVS, TP53, TNFRSF1A, STAT2, DDX58, PPP2CA, TRADD, RELA, MAPK9, EGF, SOS2, PIK3R2, MAPK14, IFNA4, IFNA16, SOCS3, PIAS1, MAPK8, IFNA8, IFNA6, IFNA10, IRF1, IFNA21, IFNA5, IFNA1, IKBKB, TNF, IKBKE, IRF7, CHUK, AKT3, RIPK1, PIK3CD, AKT2, MAPK1, IFNA14, IFNA17, TRAF6, IKBKG, TRAF3, JAK1, PIK3R5, IFNB1, EIF2AK2, MAPK3, NFKB1, TRAF2, IRF3, RAF1, PIK3CB, TYK2, EIF2AK3, PIK3CA, IFNAR2, EIF2S1, KRAS, EGFR, CXCL8, STAT3, NRAS, AKT1	1481	130	5892	2.846081130213473	5.460212419344886E-26	1.4368980050907596E-27	2.7450356567845862E-25
KEGG_PATHWAY	hsa04720:Long-term potentiation	58	3.1199569661108124	3.523042516609832E-28	ITPR3, PRKACG, PPP3CA, PLCB3, ARAF, GRIA2, GRIN2A, ADCY1, PPP1CA, PLCB4, CALML5, CALM3, CALML3, PPP1R1A, GRIN2D, CAMK2A, PRKACA, MAP2K2, PRKACB, PPP3R1, BRAF, PLCB2, PPP1CB, PRKCB, GRIA1, RPS6KA1, RPS6KA6, CAMK2G, CAMK2B, CAMK2D, PPP1CC, RPS6KA2, PRKCA, PLCB1, GRIN1, MAP2K1, CREBBP, ITPR1, PPP3CB, CALML6, MAPK1, RAP1B, RAP1A, PPP3R2, EP300, ATF4, RPS6KA3, PPP3CC, PRKCG, CACNA1C, GNAQ, MAPK3, CAMK4, ADCY8, RAF1, GRIN2B, KRAS, NRAS	1481	63	5892	3.6626475032957138	9.159910543185563E-26	2.3486950110732213E-27	4.605000524323601E-25
KEGG_PATHWAY	hsa05145:Toxoplasmosis	85	4.57235072619688	4.838157837520248E-28	STAT1, LDLR, IRAK4, PIK3CG, TLR4, MAPK12, MAPK10, SOCS1, MAP3K7, PIK3R1, HSPA8, PIK3R3, PDPK1, MAPK11, HLA-DMB, GNAI1, CASP9, MAPK13, BCL2, ITGB1, CASP8, BAD, NFKBIA, TNFRSF1A, HLA-DRA, BCL2L1, HLA-DPB1, LAMA5, MAPK9, RELA, PIK3R2, TLR2, MAPK14, TAB2, TGFB1, MAPK8, MYD88, HSPA1L, MAP2K6, IKBKB, TNF, BIRC3, NOS2, TGFB2, GNAI2, CHUK, AKT3, BIRC2, PIK3CD, JAK2, IRAK1, AKT2, IL10, MAPK1, IL10RB, LAMC1, IL12A, TRAF6, IKBKG, MAP2K3, HSPA6, GNAI3, IFNG, CIITA, JAK1, PIK3R5, CD40, NFKBIB, HSPA2, MAPK3, HLA-DRB1, TAB1, NFKB1, LAMA1, CYCS, CCR5, PIK3CB, TYK2, GNAO1, HSPA1A, PIK3CA, CASP3, ITGA6, STAT3, AKT1	1481	114	5892	2.966345641280785	1.2579210377552645E-25	3.1448025943881615E-27	6.323999575225253E-25
KEGG_PATHWAY	hsa05213:Endometrial cancer	50	2.6896180742334588	1.582834182045227E-27	CCND1, TCF7, ELK1, AXIN1, MLH1, PIK3CG, MAP2K1, CTNNA1, ARAF, CTNNB1, AKT3, PIK3R1, CDH1, PIK3CD, GRB2, PIK3R3, PDPK1, ERBB2, AKT2, APC, MAPK1, MYC, LEF1, MAP2K2, CASP9, TCF7L2, BRAF, TCF7L1, PIK3R5, GSK3B, BAD, MAPK3, AXIN2, SOS1, FOXO3, TP53, RAF1, PIK3CB, CTNNA3, ILK, PIK3CA, EGF, SOS2, KRAS, PIK3R2, PTEN, EGFR, NRAS, AKT1, CTNNA2	1481	51	5892	3.9003852722723122	4.1153688733175906E-25	1.0037485056872172E-26	2.0689367794657306E-24
KEGG_PATHWAY	hsa04725:Cholinergic synapse	82	4.410973641742872	1.679983468653028E-27	ITPR3, ADCY9, GNG4, CREB3L4, GNG10, PRKACG, PIK3CG, PLCB3, ADCY1, ADCY2, PLCB4, PIK3R1, CREB3L1, CREB3L3, PIK3R3, CREB3, CREB5, CAMK2A, ADCY5, CHRM4, CHRM2, PRKACA, GNAI1, PRKACB, GNB4, GNA11, BCL2, ADCY7, PLCB2, ADCY4, GNG13, PRKCB, KCNQ2, CREB1, CAMK2G, CAMK2B, PIK3R2, CAMK2D, PRKCA, PLCB1, KCNJ12, MAP2K1, CACNA1A, GNG2, ITPR1, GNAI2, GNG12, AKT3, GNB3, KCNJ6, PIK3CD, JAK2, GNB2, AKT2, MAPK1, FYN, FOS, CREB3L2, GNAI3, GNB5, KCNQ1, ADCY3, PIK3R5, ATF4, PRKCG, GNG8, GNAQ, CACNA1C, MAPK3, CAMK4, GNG7, ADCY6, ADCY8, GNG3, PIK3CB, GNG5, GNAO1, PIK3CA, KRAS, GNGT1, NRAS, AKT1	1481	109	5892	2.9929194878243686	4.367957018497872E-25	1.0399897663090172E-26	2.1959214847758117E-24
KEGG_PATHWAY	hsa04110:Cell cycle	89	4.787520172135556	2.3666764983811104E-27	CCNB2, CCND1, CDC16, CCNE2, ANAPC1, HDAC2, GADD45B, CDC20, SFN, CDKN2A, YWHAB, SMAD3, CDKN2B, CDC6, PLK1, MDM2, ESPL1, CUL1, CDC27, CDC25A, CDKN1A, CDK6, PKMYT1, SMC3, CDC25C, MCM6, RB1, ANAPC11, CHEK1, E2F1, ZBTB17, ANAPC10, FZR1, GSK3B, CCNE1, ABL1, CCNA2, TP53, CCNB1, YWHAE, SMC1A, ORC2, CDKN1B, TGFB1, E2F3, ANAPC5, ANAPC4, MAD2L1, ANAPC2, E2F4, CCND2, ORC4, PTTG1, CREBBP, CDK1, PTTG2, TGFB2, CDK7, YWHAG, PRKDC, HDAC1, ATM, SKP1, RBX1, MAD2L2, RBL1, MYC, CDC14A, CCND3, PCNA, CDC26, YWHAZ, SMC1B, BUB3, MAD1L1, BUB1, EP300, CCNA1, CHEK2, CDK2, SMAD2, ATR, SMAD4, CDC14B, CDK4, ORC5, TFDP1, YWHAH, TFDP2	1481	124	5892	2.8554594759425846	6.153358895790887E-25	1.431013696695555E-26	3.09350411315412E-24
KEGG_PATHWAY	hsa04261:Adrenergic signaling in cardiomyocytes	98	5.27165142549758	3.2012567055456653E-27	PPP2R2D, PPP2R2A, ADCY9, PPP2CB, CREB3L4, PPP2R1B, PPP2R1A, PIK3CG, PRKACG, PLCB3, MAPK12, ADCY2, ADCY1, PLCB4, PPP1CA, PPP2R2C, CALML5, PIK3R1, CALM3, CREB3L1, CALML3, PPP1R1A, CREB3L3, PIK3R3, PPP2R3C, CREB3, MAPK11, CAMK2A, CREB5, FXYD2, ADCY5, PPP2R2B, PRKACA, ATP1A1, GNAI1, PRKACB, MAPK13, ATP1B1, BCL2, PLCB2, ADCY7, GNAS, PPP1CB, ATP2B4, ADCY4, SCN1B, MYH7, RYR2, CREB1, PPP2CA, CAMK2G, PIK3R2, MAPK14, CAMK2B, PPP2R5E, CAMK2D, MYL2, PPP1CC, PLCB1, PRKCA, ADRB1, GNAI2, AKT3, PPP2R5C, CALML6, PIK3CD, ATP1A2, AKT2, MAPK1, ACTC1, PPP2R5D, CREB3L2, CREM, GNAI3, PPP2R5A, KCNQ1, ADCY3, PIK3R5, ATF4, PLN, KCNE1, ATF2, CACNA1C, GNAQ, PPP2R3A, MAPK3, SLC9A1, AGTR1, PPP2R5B, ADCY8, ADCY6, ADRB2, ATF6B, PIK3CB, ATP1A3, PIK3CA, RPS6KA5, AKT1	1481	144	5892	2.70751744316903	8.32326743441873E-25	1.8916516896406205E-26	4.184391399771702E-24
KEGG_PATHWAY	hsa04810:Regulation of actin cytoskeleton	125	6.724045185583647	4.884583304394165E-27	PDGFD, RRAS2, FGF10, ARAF, CFL1, ITGA3, PFN1, FGF2, ITGB8, RAC2, APC, ITGB7, CHRM4, CHRM2, INS, ACTN4, MAP2K2, PDGFB, WASL, BRAF, PAK1, ITGB1, ROCK1, ARPC5, PDGFA, SOS1, PDGFC, GNA13, ITGA1, RHOA, ITGAD, EGF, SOS2, BDKRB1, MYL7, ARHGEF1, CDC42, MAP2K1, PAK6, ARHGEF12, FGF1, ACTN2, ACTN1, MYL12A, GNG12, ITGAV, ITGA2, FGFR2, MAPK1, RAC3, MOS, ITGAM, MYL10, FGF13, FGFR3, ARPC1B, MAPK3, ARHGEF7, BDKRB2, RAF1, RDX, GSN, MYL5, PIK3CB, PTK2, PXN, PIK3CA, ACTG1, FGD3, RRAS, KRAS, EGFR, FGF12, NRAS, IQGAP2, FGF3, ITGA5, SRC, PDGFRA, PIK3CG, ACTB, WASF2, PPP1CA, PIK3R1, EZR, PIK3R3, TMSB4X, LIMK1, MRAS, GIT1, PAK3, F2, PPP1CB, MSN, VAV2, FGF7, SSH1, FGFR4, ITGB2, ITGB3, MYL12B, RAC1, FGF18, VAV1, ITGAL, PIK3R2, F2R, LIMK2, FN1, MYL2, PPP1CC, BCAR1, CRKL, PIK3CD, ARHGEF6, CRK, PIK3R5, PAK4, MYLPF, SLC9A1, PAK2, WASF1, MYLK, MYL9, DOCK1, ITGA6	1481	208	5892	2.3908611644938453	1.269991659142483E-24	2.822203686983295E-26	6.384682720060552E-24
KEGG_PATHWAY	hsa04022:cGMP-PKG signaling pathway	105	5.6481979558902635	7.754791330942507E-27	ADCY9, CREB3L4, ADCY1, ADCY2, PLCB4, NFATC2, CALML5, CALM3, IRS4, INS, INSR, MAP2K2, GNA11, MEF2D, ADCY7, ATP2B4, BAD, ROCK1, ADCY4, GNA13, RHOA, PLCB1, VDAC2, MAP2K1, ITPR1, ATP2A2, RGS2, AKT3, ATP1A2, NFATC1, AKT2, MAPK1, SRF, CREB3L2, GNAI3, ADCY3, PLN, MAPK3, PRKG1, AGTR1, BDKRB2, SLC25A4, ADCY6, IRS2, RAF1, ADRB2, MEF2C, PIK3CB, SLC8A1, PIK3CA, AKT1, ITPR3, PRKG2, PIK3CG, PPP3CA, PLCB3, IRS1, PPP1CA, PRKCE, PIK3R1, CALML3, CREB3L1, CREB3L3, PIK3R3, CREB3, CREB5, FXYD2, ADCY5, GNAI1, ATP1A1, PPP3R1, ATP1B1, PLCB2, PPP1CB, CREB1, PIK3R2, VDAC3, PPP1CC, ADRB1, GNAI2, PPP3CB, NPR1, SLC25A5, CALML6, PIK3CD, NOS3, NFATC3, PPP3R2, ATF4, PIK3R5, NPPB, PPP3CC, TRPC6, GNAQ, CACNA1C, ATF2, ATP2A3, ADCY8, MYLK, VASP, ATF6B, PDE3B, MYL9, ATP1A3, NFATC4	1481	161	5892	2.5946041159028854	2.0162457460450518E-24	4.3831429261848953E-26	1.0136357417387716E-23
KEGG_PATHWAY	hsa04917:Prolactin signaling pathway	61	3.28133405056482	9.770482190742976E-27	CCND1, STAT1, SRC, TNFRSF11A, TNFSF11, PIK3CG, MAPK12, MAPK10, STAT5A, SOCS5, SOCS1, PIK3R1, SOCS4, SOCS7, GRB2, PIK3R3, MAPK11, INS, MAP2K2, SHC1, MAPK13, SHC2, GSK3B, SOS1, CISH, FOXO3, ESR2, SHC3, SHC4, RELA, MAPK9, SOS2, CGA, MAPK14, PIK3R2, SOCS2, SOCS3, MAPK8, PRL, IRF1, CCND2, MAP2K1, AKT3, PIK3CD, JAK2, STAT5B, AKT2, MAPK1, FOS, PIK3R5, MAPK3, NFKB1, PRLR, RAF1, ESR1, PIK3CB, PIK3CA, KRAS, STAT3, NRAS, AKT1	1481	70	5892	3.4668853091540464	2.540325369593174E-24	5.404947594879093E-26	1.2771085049113156E-23
KEGG_PATHWAY	hsa04919:Thyroid hormone signaling pathway	82	4.410973641742872	3.710546587506153E-26	CCND1, STAT1, SRC, HDAC2, PIK3CG, TSC2, PRKACG, ACTB, PLCB3, FOXO1, PLCB4, NCOA3, PIK3R1, NOTCH2, PIK3R3, PDPK1, MDM2, PLCG2, FXYD2, RHEB, PRKACA, MAP2K2, ATP1A1, PRKACB, CASP9, ATP1B1, PLCB2, TBC1D4, GSK3B, SIN3A, BAD, PRKCB, ITGB3, MED14, TP53, NOTCH4, MED13L, PIK3R2, RXRG, PLCB1, NCOR1, PRKCA, HDAC3, NCOA2, MAP2K1, CREBBP, CTNNB1, HDAC1, NOTCH1, AKT3, PIK3CD, ITGAV, ATP1A2, RXRB, AKT2, MAPK1, MYC, MTOR, NOTCH3, PLCE1, PIK3R5, EP300, THRB, PLN, THRA, HIF1A, PRKCG, PLCG1, MAPK3, SLC9A1, RAF1, ESR1, RCAN2, PIK3CB, ATP1A3, RCAN1, PIK3CA, ACTG1, KRAS, MED1, NRAS, AKT1	1481	112	5892	2.912752001543359	9.647421127515997E-24	2.009879401565833E-25	4.850088779920714E-23
KEGG_PATHWAY	hsa05212:Pancreatic cancer	57	3.066164604626143	2.928664765869514E-25	CCND1, TGFBR1, STAT1, PIK3CG, CDKN2A, MAPK10, ARAF, SMAD3, PIK3R1, PIK3R3, RAC2, CDK6, CASP9, BRAF, RB1, E2F1, BAD, RAC1, TP53, BCL2L1, TGFBR2, RELA, MAPK9, EGF, VEGFA, PIK3R2, TGFB1, E2F3, MAPK8, CDC42, IKBKB, MAP2K1, TGFB2, CHUK, AKT3, PIK3CD, ARHGEF6, ERBB2, AKT2, MAPK1, RAC3, IKBKG, JAK1, PIK3R5, MAPK3, NFKB1, RAF1, SMAD2, PIK3CB, SMAD4, CDK4, PIK3CA, BRCA2, KRAS, EGFR, AKT1, STAT3	1481	65	5892	3.488744611229419	7.614528391260736E-23	1.553985385971579E-24	3.8280840264667075E-22
KEGG_PATHWAY	hsa04071:Sphingolipid signaling pathway	79	4.249596557288865	9.763968365702194E-25	PPP2R2D, PPP2R2A, PPP2CB, PPP2R1B, PPP2R1A, PIK3CG, PLCB3, MAPK12, MAPK10, PLCB4, PRKCE, PPP2R2C, PIK3R1, PIK3R3, MAP3K5, PDPK1, RAC2, PPP2R3C, MAPK11, PPP2R2B, GNAI1, MAP2K2, MAPK13, BCL2, PLCB2, ROCK1, PRKCB, RAC1, TP53, TNFRSF1A, GNA13, PLD1, BAX, PPP2CA, RHOA, TRADD, RELA, MAPK9, PTEN, MAPK14, PIK3R2, BID, PPP2R5E, MAPK8, PRKCA, PLCB1, TNF, MAP2K1, GNAI2, AKT3, PPP2R5C, PIK3CD, NOS3, AKT2, MAPK1, PPP2R5D, FYN, RAC3, GNAI3, PPP2R5A, GAB2, PIK3R5, PRKCG, GNAQ, PPP2R3A, MAPK3, S1PR3, NFKB1, TRAF2, PLD2, PPP2R5B, BDKRB2, RAF1, PIK3CB, PIK3CA, KRAS, NRAS, AKT1, PRKCZ	1481	109	5892	2.8834224333917695	2.5386317750825707E-22	5.077263550165141E-24	1.2762570769882426E-21
KEGG_PATHWAY	hsa04916:Melanogenesis	73	3.9268423883808503	1.6512886266808314E-24	FZD6, FZD4, ADCY9, TCF7, CREB3L4, PRKACG, PLCB3, WNT10A, WNT5B, ADCY1, ADCY2, PLCB4, FZD2, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, FZD5, CREB3, CAMK2A, ADCY5, PRKACA, LEF1, GNAI1, MAP2K2, FZD9, PRKACB, TCF7L2, TCF7L1, ADCY7, PLCB2, GNAS, GSK3B, ADCY4, PRKCB, CREB1, CAMK2G, DVL2, DVL1, CAMK2B, CAMK2D, KITLG, PLCB1, PRKCA, MAP2K1, CREBBP, CTNNB1, GNAI2, MITF, POMC, CALML6, MAPK1, WNT1, FZD7, FZD8, CREB3L2, WNT3A, GNAI3, ADCY3, EP300, PRKCG, GNAQ, MAPK3, FZD10, DVL3, ADCY6, ADCY8, KIT, RAF1, GNAO1, KRAS, NRAS	1481	97	5892	2.9940483234370756	4.293350429370161E-22	8.418334175235611E-24	2.158414199040724E-21
KEGG_PATHWAY	hsa04068:FoxO signaling pathway	88	4.733727810650888	3.29094422885601E-24	CCNB2, CCND1, IGF1, TGFBR1, GADD45B, PIK3CG, ATG12, MAPK12, BCL6, ARAF, MAPK10, SMAD3, FOXO1, IRS1, CDKN2B, PIK3R1, PLK1, GRB2, PIK3R3, PDPK1, MDM2, MAPK11, IRS4, INS, CDKN1A, INSR, GABARAP, MAP2K2, MAPK13, BRAF, BCL2L11, PRMT1, SOS1, USP7, FOXO3, FASLG, IGF1R, CCNB1, TGFBR2, KLF2, MAPK9, EGF, SOS2, PIK3R2, MAPK14, PTEN, CDKN1B, TGFB1, FOXO6, MAPK8, CCND2, IKBKB, IL7R, GABARAPL2, MAP2K1, CREBBP, TGFB2, IL6, RAG1, CHUK, FBXO32, ATM, AKT3, GABARAPL1, PIK3CD, AKT2, CSNK1E, IL10, MAPK1, FOXO4, PRKAA1, PIK3R5, EP300, PCK1, MAPK3, CDK2, IRS2, RAF1, SLC2A4, SMAD2, PIK3CB, SMAD4, PIK3CA, KRAS, EGFR, STAT3, NRAS, AKT1	1481	130	5892	2.6930660156858672	8.556454995025626E-22	1.645472114428005E-23	4.3016227672395156E-21
KEGG_PATHWAY	hsa04650:Natural killer cell mediated cytotoxicity	79	4.249596557288865	3.953334776567541E-23	PTK2B, PPP3CA, PIK3CG, ARAF, NFATC2, PIK3R1, PTPN6, GRB2, PIK3R3, RAC2, PLCG2, MAP2K2, PPP3R1, SHC1, BRAF, SHC2, PAK1, VAV2, IFNAR1, PRKCB, KIR2DL5A, ITGB2, SOS1, RAC1, FASLG, ICAM2, VAV1, ITGAL, SHC3, SHC4, SOS2, BID, PIK3R2, IFNA4, IFNA16, IFNA8, IFNA6, IFNA10, CD247, IFNA21, TNFRSF10B, LCK, IFNA5, IFNA1, PRKCA, TNF, MAP2K1, PPP3CB, LCP2, PIK3CD, NFATC1, ZAP70, SYK, PTPN11, MAPK1, IFNA14, FYN, RAC3, IFNA17, TNFRSF10A, IFNG, KIR2DL2, PPP3R2, PIK3R5, PPP3CC, IFNB1, PRKCG, PLCG1, KIR2DL4, MAPK3, RAF1, PIK3CB, PIK3CA, FAS, IFNAR2, CASP3, TYROBP, KRAS, NRAS	1481	113	5892	2.7813543826522378	1.0278670419075607E-20	1.9393717771840766E-22	5.1674394030415325E-20
KEGG_PATHWAY	hsa05210:Colorectal cancer	53	2.850995158687466	2.0744376994131107E-22	CCND1, TGFBR1, TCF7, AXIN1, PIK3CG, MAPK10, ARAF, SMAD3, PIK3R1, PIK3R3, RAC2, APC, LEF1, CASP9, BCL2, BRAF, TCF7L2, TCF7L1, BAD, GSK3B, AXIN2, RAC1, TP53, JUN, TGFBR2, BAX, RHOA, MAPK9, PIK3R2, TGFB1, MAPK8, MLH1, MAP2K1, TGFB2, CTNNB1, AKT3, PIK3CD, AKT2, MAPK1, RAC3, MYC, FOS, PIK3R5, MAPK3, CYCS, RAF1, SMAD2, PIK3CB, SMAD4, PIK3CA, CASP3, KRAS, AKT1	1481	62	5892	3.4008843196619547	5.393538018474088E-20	9.988033367544607E-22	2.71151615356221E-19
KEGG_PATHWAY	hsa04540:Gap junction	63	3.388918773534158	1.660304966992308E-21	TUBB, TUBB4A, ITPR3, ADCY9, TUBA1A, PRKG2, SRC, PDGFD, PDGFRA, PRKACG, PLCB3, ADCY1, TUBB4B, ADCY2, CSNK1D, PLCB4, GRB2, TUBA4A, TUBA1C, ADCY5, PRKACA, GNAI1, MAP2K2, PDGFB, PRKACB, GNA11, ADCY7, PLCB2, GNAS, ADCY4, PRKCB, PDGFA, SOS1, PDGFC, SOS2, EGF, DRD2, PRKCA, PLCB1, MAP2K1, CDK1, MAPK7, ITPR1, ADRB1, MAP2K5, GNAI2, MAPK1, TJP1, GNAI3, TUBB3, ADCY3, PRKCG, GNAQ, MAPK3, PRKG1, ADCY6, ADCY8, RAF1, MAP3K2, TUBB2A, KRAS, EGFR, NRAS	1481	83	5892	3.0197440674243228	4.316792914180001E-19	7.848714389418184E-21	2.1701995384642696E-18
KEGG_PATHWAY	hsa04662:B cell receptor signaling pathway	55	2.9585798816568047	4.6388851823054775E-21	PIK3CG, PPP3CA, INPPL1, BTK, NFATC2, PIK3R1, PTPN6, PIK3R3, GRB2, RAC2, PLCG2, MAP2K2, PPP3R1, GSK3B, NFKBIA, VAV2, SOS1, BLNK, RAC1, JUN, INPP5D, VAV1, RELA, SOS2, PIK3R2, BCL10, IKBKB, MAP2K1, MALT1, PPP3CB, CHUK, AKT3, PIK3CD, NFATC1, SYK, AKT2, MAPK1, RAC3, NFATC3, FOS, NFKBIE, IKBKG, LYN, PPP3R2, PIK3R5, NFKBIB, PPP3CC, MAPK3, NFKB1, RAF1, PIK3CB, PIK3CA, KRAS, NRAS, AKT1	1481	68	5892	3.2178178496246574	1.2061101473994242E-18	2.1537681203561148E-20	6.063528497337037E-18
KEGG_PATHWAY	hsa04370:VEGF signaling pathway	50	2.6896180742334588	8.222725240926481E-21	SRC, PIK3CG, PPP3CA, MAPK12, NFATC2, PIK3R1, PIK3R3, RAC2, PLCG2, MAPK11, MAP2K2, CASP9, MAPK13, PPP3R1, MAPKAPK2, SHC2, BAD, PTGS2, PRKCB, RAC1, KDR, VEGFA, MAPK14, PIK3R2, HSPB1, CDC42, PRKCA, MAP2K1, PPP3CB, AKT3, PIK3CD, NOS3, AKT2, MAPK1, RAC3, SH2D2A, PPP3R2, PIK3R5, PPP3CC, PRKCG, PLCG1, MAPK3, RAF1, PTK2, PXN, PIK3CB, PIK3CA, KRAS, NRAS, AKT1	1481	59	5892	3.3715194726421682	2.137908562640885E-18	3.750716776562956E-20	1.074799803502595E-17
KEGG_PATHWAY	hsa04064:NF-kappa B signaling pathway	63	3.388918773534158	1.3385528875310797E-20	IRAK4, MAP3K14, TNFRSF11A, TNFSF11, TLR4, TICAM1, BTK, MAP3K7, IL1R1, PLCG2, TICAM2, BCL2, CFLAR, NFKBIA, PTGS2, PIAS4, BLNK, TNFRSF1A, BCL2L1, TIRAP, RELB, CXCL12, DDX58, CCL19, TRADD, RELA, PLAU, TAB2, IL1B, CSNK2A2, MYD88, LCK, BCL10, IKBKB, CSNK2B, BIRC3, TNF, MALT1, CSNK2A1, TRAF5, CHUK, ATM, RIPK1, BIRC2, NFKB2, ZAP70, IRAK1, SYK, TRAF6, IKBKG, UBE2I, TRAF3, LYN, VCAM1, CD40, PLCG1, CCL4, TAB1, NFKB1, TRAF2, CCL13, PRKCQ, CXCL8	1481	85	5892	2.948691265837868	3.480237507580807E-18	6.000409495828978E-20	1.7496345047936143E-17
KEGG_PATHWAY	hsa05222:Small cell lung cancer	63	3.388918773534158	1.3385528875310797E-20	CCND1, CCNE2, PIK3CG, CDKN2B, COL4A5, ITGA3, COL4A1, PIK3R1, PIK3R3, CDK6, CKS2, CASP9, BCL2, RB1, E2F1, PIAS2, ITGB1, COL4A2, NFKBIA, PTGS2, CCNE1, TP53, TRAF4, COL4A6, BCL2L1, LAMA5, RELA, PTEN, PIK3R2, E2F3, COL4A3, FN1, RXRG, IKBKB, CKS1B, BIRC3, NOS2, TRAF5, CHUK, AKT3, BIRC2, PIK3CD, ITGAV, ITGA2, RXRB, AKT2, MYC, LAMC1, TRAF6, IKBKG, TRAF3, PIK3R5, NFKB1, CDK2, TRAF2, LAMA1, CYCS, PTK2, PIK3CB, CDK4, PIK3CA, ITGA6, AKT1	1481	85	5892	2.948691265837868	3.480237507580807E-18	6.000409495828978E-20	1.7496345047936143E-17
KEGG_PATHWAY	hsa04931:Insulin resistance	73	3.9268423883808503	1.9490659377454752E-20	CREB3L4, PIK3CG, MAPK10, PYGL, FOXO1, IRS1, PPP1CA, PRKCE, PIK3R1, SREBF1, CREB3L1, CREB3L3, PIK3R3, PDPK1, CREB3, CREB5, PPP1R3A, INS, INSR, PPARA, GYS1, TBC1D4, PPP1CB, GSK3B, NFKBIA, PPP1R3E, CREB1, TNFRSF1A, RPS6KA1, CRTC2, RPS6KA6, MAPK9, RELA, PIK3R2, PTEN, SOCS3, MAPK8, PPP1CC, RPS6KB1, IKBKB, RPS6KA2, TNF, PPP1R3B, PPP1R3C, IL6, AKT3, PTPRF, PIK3CD, PYGM, NOS3, AKT2, PTPN11, PYGB, MTOR, CREB3L2, GYS2, PRKAA1, PIK3R5, RPS6KA3, PPP1R3D, PCK1, NFKB1, PRKCD, PTPN1, IRS2, SLC2A4, PRKCQ, PIK3CB, CPT1A, PIK3CA, STAT3, AKT1, PRKCZ	1481	107	5892	2.7142307231158536	5.067571438138236E-18	8.589104132437687E-20	2.547641597551913E-17
KEGG_PATHWAY	hsa04750:Inflammatory mediator regulation of TRP channels	66	3.5502958579881656	2.5442603770164296E-20	IGF1, ITPR3, ADCY9, SRC, PRKACG, PIK3CG, MAPK12, PLCB3, MAPK10, ADCY1, ADCY2, PPP1CA, PLCB4, PRKCE, CALML5, IL1R1, CALM3, PIK3R1, CALML3, PIK3R3, PLCG2, CAMK2A, MAPK11, ADCY5, PRKACA, PRKACB, MAPK13, ADCY7, PLCB2, GNAS, PPP1CB, ADCY4, PRKCB, CAMK2G, MAPK9, PIK3R2, CAMK2B, MAPK14, BDKRB1, PRKCH, CAMK2D, MAPK8, IL1B, NGF, PPP1CC, MAP2K6, PLCB1, PRKCA, ITPR1, CALML6, PIK3CD, TRPV4, NTRK1, MAP2K3, ADCY3, PIK3R5, PRKCG, GNAQ, PLCG1, PRKCD, BDKRB2, ADCY6, ADCY8, PRKCQ, PIK3CB, PIK3CA	1481	92	5892	2.8540645274931746	6.615076980242717E-18	1.1025128300404527E-19	3.325625596324296E-17
KEGG_PATHWAY	hsa04210:Apoptosis	51	2.743410435718128	3.951237413797168E-20	CSF2RB, MAP3K14, PIK3CG, PIK3R1, PIK3R3, CASP7, CASP9, CASP6, BCL2, CFLAR, CASP8, BAD, NFKBIA, TP53, TNFRSF1A, FASLG, BCL2L1, BAX, RELA, IL3RA, TRADD, PIK3R2, BID, NGF, TNFRSF10B, IKBKB, DFFA, BIRC3, TNF, CHUK, ATM, RIPK1, AKT3, BIRC2, PIK3CD, FADD, AKT2, NTRK1, IKBKG, TNFRSF10A, PIK3R5, NFKB1, CAPN1, TRAF2, CASP10, CYCS, PIK3CB, PIK3CA, FAS, CASP3, AKT1	1481	62	5892	3.2725490623162203	1.0273217275872638E-17	1.6841339796512521E-19	5.164697921321762E-17
KEGG_PATHWAY	hsa04622:RIG-I-like receptor signaling pathway	54	2.9047875201721354	5.146919503475756E-20	TBK1, MAPK12, ATG12, MAPK10, MAP3K7, SIKE1, RNF125, MAPK11, PIN1, TMEM173, IFIH1, MAPK13, CASP8, NFKBIA, MAVS, DDX58, RELA, MAPK9, TRADD, MAPK14, IFNA4, IFNA16, IFNA8, MAPK8, IFNA6, IFNA10, IFNA21, IFNA5, IFNA1, IKBKB, TNF, IKBKE, TANK, IRF7, CHUK, RIPK1, FADD, IFNA14, ATG5, IFNA17, IL12A, ISG15, IKBKG, TRAF6, TRAF3, MAP3K1, NFKBIB, IFNB1, NFKB1, TRAF2, CASP10, IRF3, CXCL8, CYLD	1481	68	5892	3.1593120705405724	1.3381990709036966E-17	2.1583855982317685E-19	6.727584722697263E-17
KEGG_PATHWAY	hsa04921:Oxytocin signaling pathway	91	4.895104895104895	7.184529541956488E-20	CCND1, ITPR3, ADCY9, SRC, ELK1, PPP3CA, PIK3CG, PRKACG, ACTB, PLCB3, ADCY1, ADCY2, PPP1CA, PLCB4, NFATC2, CALML5, PIK3R1, CALM3, CALML3, PIK3R3, CAMK2A, ADCY5, CDKN1A, PRKACA, GNAI1, MAP2K2, PRKACB, PPP3R1, ADCY7, PLCB2, GNAS, PPP1CB, PTGS2, ROCK1, ADCY4, PRKCB, RYR2, JUN, RHOA, CAMK2G, PIK3R2, CAMK2B, CAMK2D, PPP1CC, PLCB1, PRKCA, KCNJ12, MAP2K1, MAPK7, KCNJ9, MAP2K5, ITPR1, GNAI2, PPP3CB, RGS2, NPR1, CALML6, PIK3CD, KCNJ6, NFATC1, NOS3, MAPK1, NFATC3, FOS, GNAI3, PRKAA1, ADCY3, PPP3R2, PIK3R5, PPP3CC, PRKCG, GNAQ, CACNA1C, MAPK3, CAMK4, CAMKK2, ADCY6, ADCY8, RAF1, MEF2C, MYLK, PIK3CB, MYL9, GNAO1, RCAN1, PIK3CA, NFATC4, ACTG1, KRAS, EGFR, NRAS	1481	151	5892	2.397574575975603	1.8679776809086868E-17	2.965043937950297E-19	9.390963109796634E-17
KEGG_PATHWAY	hsa05223:Non-small cell lung cancer	47	2.5282409897794516	7.447890495871728E-20	RASSF5, CCND1, RXRG, PRKCA, ALK, PIK3CG, CDKN2A, MAP2K1, ARAF, AKT3, PIK3R1, PIK3CD, GRB2, PIK3R3, PDPK1, PLCG2, RXRB, ERBB2, AKT2, MAPK1, CDK6, MAP2K2, CASP9, BRAF, RB1, E2F1, PIK3R5, BAD, PRKCG, PLCG1, MAPK3, PRKCB, SOS1, FOXO3, TP53, RAF1, PIK3CB, PIK3CA, CDK4, EGF, SOS2, KRAS, PIK3R2, EGFR, E2F3, NRAS, AKT1	1481	55	5892	3.3997176355042664	1.9364515289266493E-17	3.0257055139478895E-19	9.735204578682761E-17
KEGG_PATHWAY	hsa04611:Platelet activation	80	4.303388918773534	1.8348646429232215E-19	ITPR3, ADCY9, SRC, PRKG2, PIK3CG, PRKACG, ACTB, MAPK12, PLCB3, BTK, ADCY1, ADCY2, PPP1CA, PLCB4, PIK3R1, PIK3R3, COL2A1, VAMP8, PLCG2, MAPK11, ADCY5, PRKACA, GNAI1, PRKACB, MAPK13, ADCY7, PLCB2, GNAS, PPP1CB, ITGB1, TLN1, ORAI1, ROCK1, ADCY4, ITGB3, COL1A2, MYL12B, GNA13, RHOA, VWF, PIK3R2, MAPK14, F2R, GP1BA, ARHGEF1, PPP1CC, PLCB1, ITPR1, ARHGEF12, GNAI2, AKT3, MYL12A, PRKCI, LCP2, PIK3CD, ITGA2, NOS3, AKT2, SYK, MAPK1, FYN, STIM1, RAP1A, LYN, RAP1B, GNAI3, ADCY3, PIK3R5, COL1A1, GNAQ, MAPK3, PRKG1, ADCY6, ADCY8, MYLK, VASP, PIK3CB, PIK3CA, ACTG1, AKT1, PRKCZ	1481	126	5892	2.5259637953763545	4.770648071600376E-17	7.339458571692886E-19	2.39836805911021E-16
KEGG_PATHWAY	hsa04310:Wnt signaling pathway	83	4.464766003227542	1.220713847875757E-18	FZD6, CCND1, FZD4, SFRP2, TCF7, AXIN1, PPP3CA, PRKACG, PLCB3, MAPK10, WNT10A, LRP5, WNT5B, PLCB4, NFATC2, MAP3K7, FZD2, RAC2, FZD5, APC, CAMK2A, CUL1, PRKACA, LEF1, FZD9, RUVBL1, PRKACB, PPP3R1, TCF7L2, FBXW11, TCF7L1, PLCB2, GSK3B, PRKCB, AXIN2, RAC1, TP53, JUN, RHOA, CAMK2G, MAPK9, DVL2, DVL1, CAMK2B, CAMK2D, FOSL1, MAPK8, CSNK2A2, CCND2, PSEN1, BTRC, PLCB1, PRKCA, CSNK2B, CREBBP, CSNK2A1, CTNNB1, PPP3CB, CTBP1, NFATC1, SKP1, RBX1, CSNK1E, WNT1, FZD7, RAC3, MYC, NFATC3, CCND3, FZD8, WNT3A, PPP3R2, EP300, PPARD, PPP3CC, PRKCG, CSNK1A1, MMP7, FZD10, DVL3, SMAD4, NFATC4, LRP6	1481	136	5892	2.4279898319895143	3.1738560044769683E-16	4.808872734056013E-18	1.595606037399263E-15
KEGG_PATHWAY	hsa05211:Renal cell carcinoma	49	2.63582571274879	1.5037555187150147E-18	ARNT, EPAS1, PIK3CG, ARAF, PIK3R1, PIK3R3, GRB2, MAP2K2, PAK3, PDGFB, BRAF, PAK1, SOS1, RAC1, JUN, VEGFA, SOS2, PIK3R2, TGFB1, CDC42, MET, CREBBP, MAP2K1, PAK6, TGFB2, AKT3, CRKL, PIK3CD, HGF, PTPN11, RBX1, AKT2, MAPK1, CRK, RAP1B, RAP1A, EP300, PIK3R5, PAK4, HIF1A, MAPK3, PAK2, GAB1, RAF1, PIK3CB, PIK3CA, KRAS, AKT1, NRAS	1481	61	5892	3.19575829357656	3.909764348659038E-16	5.835469177103042E-18	1.9655723481874896E-15
KEGG_PATHWAY	hsa05218:Melanoma	53	2.850995158687466	4.720691632905795E-18	CCND1, IGF1, FGF3, PDGFD, PDGFRA, PIK3CG, CDKN2A, FGF10, ARAF, FGF2, PIK3R1, CDH1, MDM2, PIK3R3, CDKN1A, CDK6, MAP2K2, PDGFB, BRAF, RB1, E2F1, BAD, FGF7, PDGFA, PDGFC, TP53, FGF18, IGF1R, EGF, PTEN, PIK3R2, E2F3, MET, MAP2K1, FGF1, MITF, AKT3, PIK3CD, HGF, AKT2, MAPK1, FGF13, PIK3R5, MAPK3, RAF1, PIK3CB, PIK3CA, CDK4, KRAS, EGFR, AKT1, NRAS, FGF12	1481	70	5892	3.0122118259863027	1.2273798245555067E-15	1.8049703302286865E-17	6.170458443862355E-15
KEGG_PATHWAY	hsa05031:Amphetamine addiction	49	2.63582571274879	5.024025193693185E-18	PPP1CC, PRKCA, CREB3L4, GRIN1, PRKACG, PPP3CA, GRIA2, GRIA3, GRIN2A, PPP3CB, PPP1CA, STX1A, CALML5, CALML6, CALM3, CREB3L1, CALML3, PPP1R1B, CREB3L3, GRIA4, GRIN2D, CREB3, CREB5, CAMK2A, ADCY5, PRKACA, FOS, PRKACB, PPP3R1, CREB3L2, PPP3R2, GNAS, ATF4, PPP1CB, PPP3CC, PRKCG, ATF2, CACNA1C, PRKCB, CAMK4, CREB1, GRIA1, JUN, ATF6B, CAMK2G, GRIN2B, CAMK2B, FOSB, CAMK2D	1481	62	5892	3.1442138049704864	1.3062465503602281E-15	1.8931109425510552E-17	6.566948466303255E-15
KEGG_PATHWAY	hsa04664:Fc epsilon RI signaling pathway	51	2.743410435718128	5.07480628697816E-18	PIK3CG, MAPK12, MAPK10, BTK, PIK3R1, GRB2, PDPK1, PIK3R3, RAC2, PLCG2, MAPK11, MAP2K2, MAPK13, VAV2, PRKCB, SOS1, RAC1, IL5, INPP5D, VAV1, MAPK9, MAP2K4, SOS2, MAPK14, PIK3R2, MAPK8, MAP2K6, PRKCA, TNF, MAP2K1, AKT3, LCP2, PIK3CD, SYK, AKT2, MAPK1, FYN, RAC3, MAP2K3, LYN, GAB2, PIK3R5, PLCG1, MAPK3, RAF1, PIK3CB, PIK3CA, KRAS, MAP2K7, NRAS, AKT1	1481	66	5892	3.0742127555091767	1.3194496346143216E-15	1.8849280494490307E-17	6.63332488955121E-15
KEGG_PATHWAY	hsa04390:Hippo signaling pathway	85	4.57235072619688	8.128824873018048E-17	FZD6, CCND1, FZD4, PPP2R2D, PPP2R2A, TGFBR1, TCF7, PPP2CB, AXIN1, PPP2R1B, PPP2R1A, ACTB, SMAD1, CTNNA1, YWHAB, WNT10A, SMAD3, STK3, WNT5B, CSNK1D, PPP1CA, PPP2R2C, FZD2, CDH1, LATS1, AJUBA, FZD5, APC, PPP2R2B, LEF1, FZD9, TCF7L2, FBXW11, TCF7L1, TEAD4, SOX2, PPP1CB, GSK3B, LLGL2, YAP1, ITGB2, AXIN2, TGFBR2, TP53BP2, YWHAE, PPP2CA, DVL2, DVL1, TGFB1, DLG1, CCND2, PPP1CC, BTRC, BBC3, CTGF, WWTR1, TGFB2, FGF1, CTNNB1, YWHAG, PRKCI, CSNK1E, WNT1, FZD7, MYC, BMPR2, CCND3, FZD8, YWHAZ, WNT3A, DLG4, TEAD3, GLI2, FZD10, TEAD1, DVL3, SMAD2, NF2, CTNNA3, SMAD4, ACTG1, YWHAH, TP73, CTNNA2, PRKCZ	1481	148	5892	2.2848878588243884	2.886579864025407E-14	4.440892098500626E-16	1.4432899320127035E-13
KEGG_PATHWAY	hsa04670:Leukocyte transendothelial migration	71	3.8192576654115116	1.0943493701974626E-16	RASSF5, PTK2B, ACTB, PIK3CG, MMP9, CTNNA1, MAPK12, CXCR4, PIK3R1, EZR, PIK3R3, RAC2, CTNND1, PLCG2, MAPK11, JAM2, ACTN4, GNAI1, MAPK13, ITGB1, MSN, ROCK1, VAV2, PRKCB, ITGB2, RAC1, MYL12B, ITK, CXCL12, VAV1, ITGAL, RHOA, PIK3R2, MAPK14, MYL7, MYL2, CDC42, PRKCA, NCF1, CTNNB1, GNAI2, ACTN2, ACTN1, TXK, MYL12A, BCAR1, PIK3CD, PTPN11, ITGAM, MYL10, RAP1A, RAP1B, GNAI3, VCAM1, PIK3R5, JAM3, PRKCG, MYLPF, PLCG1, VASP, MYL5, NCF4, PXN, PTK2, CTNNA3, MYL9, PIK3CB, MMP2, PIK3CA, ACTG1, F11R, CTNNA2	1481	114	5892	2.4777710650698324	2.886579864025407E-14	4.440892098500626E-16	1.4432899320127035E-13
KEGG_PATHWAY	hsa05100:Bacterial invasion of epithelial cells	51	2.743410435718128	3.11206418030416E-16	ITGA5, SRC, CAV2, ACTB, PIK3CG, CTNNA1, WASF2, CAV1, PIK3R1, CDH1, PIK3R3, SHC1, WASL, SHC2, ITGB1, CBLB, ARPC5, RAC1, SHC3, SHC4, RHOA, ILK, PIK3R2, CAV3, FN1, CDC42, CBL, MET, CTNNB1, CRKL, BCAR1, PIK3CD, RHOG, MAD2L2, CLTC, ARHGAP10, CRK, PIK3R5, ARPC1B, ELMO1, GAB1, WASF1, CBLC, CTNNA3, PTK2, PXN, PIK3CB, PIK3CA, DOCK1, ACTG1, CTNNA2	1481	70	5892	2.8985434551943663	8.659739592076221E-14	1.2212453270876722E-15	4.3298697960381105E-13
KEGG_PATHWAY	hsa05146:Amoebiasis	66	3.5502958579881656	9.969922332037859E-16	C8B, TLR4, PRKACG, PIK3CG, PLCB3, COL4A5, ADCY1, PLCB4, COL4A1, IL1R1, PIK3R1, PIK3R3, COL2A1, PRKACA, ACTN4, PRKACB, GNA11, PLCB2, GNAS, C9, COL4A2, PRKCB, ITGB2, COL1A2, COL4A6, LAMA5, RELA, TLR2, PIK3R2, HSPB1, TGFB1, IL1B, COL4A3, FN1, PRKCA, PLCB1, IL1R2, GNA15, TNF, NOS2, IL6, RAB5B, TGFB2, ACTN2, ACTN1, PIK3CD, IL10, GNAL, LAMC1, ITGAM, IL12A, IFNG, PIK3R5, PRKCG, COL1A1, GNAQ, NFKB1, LAMA1, RAB7A, RAB5C, RAB5A, PTK2, PIK3CB, PIK3CA, CASP3, CXCL8	1481	105	5892	2.5007041574225912	2.5979218776228663E-13	3.552713678800501E-15	1.3100631690576847E-12
KEGG_PATHWAY	hsa04666:Fc gamma R-mediated phagocytosis	55	2.9585798816568047	2.688721098928963E-15	PIK3CG, WASF2, CFL1, INPPL1, PRKCE, PIK3R1, PIK3R3, RAC2, LIMK1, PLCG2, WASL, PAK1, PTPRC, VAV2, ARPC5, PRKCB, RAC1, PLD1, INPP5D, VAV1, PIK3R2, LIMK2, CDC42, RPS6KB1, PRKCA, MAP2K1, NCF1, AKT3, CRKL, PIK3CD, SYK, AKT2, MAPK1, MARCKS, HCK, CRK, LYN, WASF3, GAB2, PIK3R5, ASAP1, ARPC1B, PRKCG, PLCG1, MAPK3, PRKCD, PLD2, RAF1, WASF1, VASP, GSN, PIK3CB, PIK3CA, ARF6, AKT1	1481	81	5892	2.7013779478330457	6.927791673660977E-13	9.2148511043888E-15	3.4861002973229915E-12
KEGG_PATHWAY	hsa04066:HIF-1 signaling pathway	61	3.28133405056482	3.2364038968671604E-15	ARNT, IGF1, GAPDH, ENO1, TLR4, PIK3CG, RPS6, PIK3R1, PIK3R3, PLCG2, CAMK2A, CDKN1A, INS, INSR, MAP2K2, BCL2, ANGPT1, ANGPT2, TFRC, FLT1, PRKCB, IGF1R, PDHB, CAMK2G, RELA, EGF, VEGFA, PIK3R2, CAMK2B, CAMK2D, CDKN1B, RPS6KB1, PRKCA, MAP2K1, CREBBP, NOS2, IL6, AKT3, PIK3CD, NOS3, ERBB2, AKT2, RBX1, MAPK1, MTOR, IFNG, PIK3R5, EP300, PRKCG, HIF1A, PLCG1, EIF4EBP1, MAPK3, NFKB1, ANGPT4, EIF4E, PIK3CB, PIK3CA, EGFR, STAT3, AKT1	1481	95	5892	2.5545470699029815	8.37108160567368E-13	1.099120794378905E-14	4.207745263329343E-12
KEGG_PATHWAY	hsa04520:Adherens junction	48	2.5820333512641205	3.411649405252978E-15	CSNK2A2, TGFBR1, TCF7, SRC, CDC42, MET, ACTB, CSNK2B, CREBBP, WASF2, CTNNA1, CSNK2A1, SMAD3, CTNNB1, ACTN2, ACTN1, MAP3K7, PTPRF, CDH1, PTPN6, RAC2, CTNND1, ERBB2, MAPK1, RAC3, FYN, INSR, ACTN4, LEF1, TJP1, WASL, TCF7L2, TCF7L1, WASF3, EP300, MAPK3, PTPN1, RAC1, IGF1R, WASF1, SMAD2, TGFBR2, CTNNA3, SMAD4, RHOA, ACTG1, EGFR, CTNNA2	1481	66	5892	2.893376711067461	8.948397578478762E-13	1.1657341758564144E-14	4.496403249731884E-12
KEGG_PATHWAY	hsa04730:Long-term depression	43	2.3130715438407745	5.071720665289952E-15	IGF1, ITPR3, PPP2CB, PRKG2, PRKCA, PLCB1, PPP1R17, PPP2R1B, PPP2R1A, PLCB3, MAP2K1, CACNA1A, ARAF, ITPR1, GRIA2, GRIA3, GNAI2, PLCB4, CRHR1, NOS1, MAPK1, MAP2K2, GNAI1, GNA11, BRAF, LYN, GNAI3, PLCB2, GNAS, PRKCG, GNAQ, MAPK3, PRKCB, PRKG1, GRIA1, IGF1R, RAF1, GNA13, GNAO1, PPP2CA, CRH, KRAS, NRAS	1481	56	5892	3.0548374650332786	1.3278267374516872E-12	1.6986412276764895E-14	6.672440377997191E-12
KEGG_PATHWAY	hsa04723:Retrograde endocannabinoid signaling	60	3.2275416890801503	8.463960701013424E-15	ITPR3, ADCY9, GNG4, GNG10, PRKACG, PLCB3, MAPK12, MAPK10, GRIA2, GRIA3, ADCY1, ADCY2, PLCB4, MAPK11, ADCY5, PRKACA, GNAI1, PRKACB, GNB4, MAPK13, ADCY7, PLCB2, PTGS2, ADCY4, GNG13, PRKCB, GRIA1, MAPK9, MAPK14, MAPK8, PRKCA, PLCB1, CACNA1A, KCNJ9, ITPR1, GNG2, GNAI2, GNG12, GNB3, KCNJ6, GRIA4, GNB2, MAPK1, GNAI3, GNB5, ADCY3, GABRG2, PRKCG, GNG8, CACNA1C, GNAQ, MAPK3, GNG7, ADCY6, ADCY8, GNG3, GNG5, GNAO1, CNR1, GNGT1	1481	94	5892	2.5393997730113353	2.1938006966593093E-12	2.7755575615628914E-14	1.1024514634527804E-11
KEGG_PATHWAY	hsa04923:Regulation of lipolysis in adipocytes	42	2.2592791823561056	1.5405838858900898E-14	ADCY9, PRKG2, PRKACG, PIK3CG, ADRB1, IRS1, ADCY1, GNAI2, ADCY2, AKT3, NPR1, PIK3R1, PIK3CD, PIK3R3, NPY, AKT2, IRS4, ADCY5, INS, PRKACA, INSR, GNAI1, PRKACB, GNAI3, ADCY7, ADCY3, GNAS, PIK3R5, PTGS2, ADCY4, PRKG1, ADCY6, ADCY8, IRS2, ADRB2, TSHR, PDE3B, PIK3CB, PIK3CA, CGA, PIK3R2, AKT1	1481	55	5892	3.038045546620834	4.012346010995316E-12	5.0182080713057076E-14	2.0172752357439094E-11
KEGG_PATHWAY	hsa05133:Pertussis	50	2.6896180742334588	3.541615990808655E-14	ITGA5, IRAK4, TLR4, MAPK12, MAPK10, TICAM1, CFL1, CALML5, CALM3, CALML3, MAPK11, TICAM2, CXCL5, GNAI1, CASP7, MAPK13, ITGB1, NLRP3, ITGB2, NOD1, TIRAP, JUN, RHOA, RELA, MAPK9, MAPK14, MAPK8, IL1B, CASP1, IRF1, MYD88, TNF, NOS2, IL6, GNAI2, CALML6, IRAK1, IL10, MAPK1, ITGAM, FOS, TRAF6, IL12A, GNAI3, MAPK3, NFKB1, IRF3, IL1A, CASP3, CXCL8	1481	73	5892	2.724926697066958	9.208189766241048E-12	1.1368683772161603E-13	4.629630012686903E-11
KEGG_PATHWAY	hsa04925:Aldosterone synthesis and secretion	52	2.797202797202797	5.2900011746109496E-14	ITPR3, ADCY9, LDLR, CREB3L4, PRKACG, PLCB3, ADCY2, ADCY1, PLCB4, PRKCE, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, CREB3, CAMK2A, CREB5, ADCY5, PRKACA, PRKACB, GNA11, ADCY7, PLCB2, GNAS, ORAI1, ADCY4, PRKCB, CREB1, CAMK2G, PRKD2, CAMK2B, CAMK2D, PRKCA, PLCB1, ITPR1, NPR1, CALML6, NR4A1, CREB3L2, ATF1, ADCY3, ATF4, PRKCG, ATF2, CACNA1C, GNAQ, AGTR1, CAMK4, ADCY6, ADCY8, ATF6B	1481	78	5892	2.652261985145172	1.3740120152760937E-11	1.6753265441593612E-13	6.907807659217724E-11
KEGG_PATHWAY	hsa04550:Signaling pathways regulating pluripotency of stem cells	76	4.088219472834857	6.701238795148862E-14	FZD6, FZD4, IGF1, AXIN1, PIK3CG, MAPK12, SMAD1, WNT10A, SMAD5, SMAD3, WNT5B, JAK3, FZD2, FGF2, PIK3R1, GRB2, PIK3R3, ACVR1, FZD5, APC, MAPK11, MAP2K2, FZD9, MAPK13, INHBA, SOX2, TCF3, GSK3B, FGFR4, AXIN2, KLF4, IGF1R, LIFR, DVL2, DVL1, PIK3R2, MAPK14, ESRRB, ID3, MAP2K1, SKIL, CTNNB1, INHBB, MEIS1, AKT3, PIK3CD, JAK2, AKT2, MAPK1, WNT1, FGFR2, FZD7, MYC, BMPR2, FZD8, SMAD9, WNT3A, JAK1, PIK3R5, PAX6, FGFR3, MAPK3, FZD10, DVL3, RAF1, SETDB1, SMAD2, PIK3CB, SMAD4, PIK3CA, IL6ST, DLX5, KRAS, STAT3, NRAS, AKT1	1481	137	5892	2.206991724865326	1.7434942378713458E-11	2.1005419625907962E-13	8.765210779415611E-11
KEGG_PATHWAY	hsa04060:Cytokine-cytokine receptor interaction	108	5.809575040344271	9.810439071797646E-14	CSF2RB, TNFRSF11A, TNFSF11, CXCR4, TNFRSF12A, IL1R1, ACVR1, CXCR5, CCR10, PDGFB, IL4R, CCL5, CCL2, PDGFA, PDGFC, LIFR, IL12RB1, CXCL12, IL2RB, IL3RA, EGF, IL2RA, TGFB1, IL1B, IFNA8, IL21R, IL9R, CNTFR, IL21, IL1R2, IL6, TGFB2, TNFRSF17, IL12RB2, TNFSF13, IL10, IL12A, CD40, CRLF2, IL13RA1, IL2, OSMR, CSF1, IL6ST, FAS, IFNAR2, EGFR, PF4, IL2RG, TGFBR1, IL22RA2, PPBP, IL11, PDGFRA, NGFR, CCL11, CSF3R, CCR3, IFNAR1, FLT1, TNFRSF1A, IL5, FASLG, IFNLR1, KDR, TGFBR2, IL5RA, CCL19, VEGFA, IFNA4, IFNA16, IFNA6, IFNA10, VEGFC, PRL, KITLG, IFNA21, VEGFB, IFNA5, IFNA1, CSF1R, GHR, IL7R, MET, TNF, IL17A, IL17RA, HGF, IL15RA, IFNA14, IL10RB, IFNA17, BMPR2, IFNG, FLT3, IFNB1, CCL4, KIT, PRLR, CCL13, CCR5, EPOR, IL1A, CCR1, CCL3, TNFRSF1B, CXCL8, CCL7	1481	225	5892	1.909628629304524	2.5517365997984598E-11	3.0375701953744283E-13	1.2828627049543684E-10
KEGG_PATHWAY	hsa04152:AMPK signaling pathway	69	3.7116729424421733	1.8664960513588565E-13	CCND1, PPP2R2D, PPP2R2A, IGF1, PPP2CB, CREB3L4, PPP2R1B, PPP2R1A, TSC2, PIK3CG, IRS1, FOXO1, PFKL, PPP2R2C, MAP3K7, PIK3R1, CREB3L1, SREBF1, CREB3L3, PIK3R3, PDPK1, PPP2R3C, CREB3, CREB5, RHEB, IRS4, PPP2R2B, INS, INSR, GYS1, CCNA2, CREB1, FOXO3, TSC1, IGF1R, CRTC2, PPP2CA, PIK3R2, PPP2R5E, PFKP, RPS6KB1, AKT1S1, CFTR, AKT3, PPP2R5C, PIK3CD, AKT2, PPP2R5D, RAB11B, MTOR, PPARG, CREB3L2, GYS2, PRKAA1, PPP2R5A, PIK3R5, CCNA1, PCK1, FASN, EIF4EBP1, PPP2R3A, PPP2R5B, CAMKK2, IRS2, SLC2A4, PIK3CB, CPT1A, PIK3CA, AKT1	1481	121	5892	2.26867037572335	4.852340751426709E-11	5.708766792622555E-13	2.4394930520088565E-10
KEGG_PATHWAY	hsa05219:Bladder cancer	33	1.7751479289940828	4.215028812454005E-13	CCND1, SRC, MMP9, MAP2K1, CDKN2A, ARAF, CDH1, MDM2, ERBB2, DAPK1, MAPK1, CDKN1A, MYC, MAP2K2, THBS1, BRAF, RB1, E2F1, FGFR3, MAPK3, TP53, RAF1, MMP2, CDK4, VEGFA, EGF, KRAS, RPS6KA5, EGFR, CXCL8, E2F3, NRAS, MMP1	1481	40	5892	3.2821742066171504	1.096034374370447E-10	1.2744250099672172E-12	5.510147893517114E-10
KEGG_PATHWAY	hsa04918:Thyroid hormone synthesis	45	2.4206562668101133	4.666548368956499E-13	ITPR3, ADCY9, PRKCA, CREB3L4, PLCB1, PRKACG, PLCB3, ITPR1, ADCY2, ADCY1, PLCB4, PDIA4, CREB3L1, CREB3L3, ATP1A2, HSP90B1, CREB3, PAX8, CREB5, FXYD2, ADCY5, HSPA5, PRKACA, ATP1A1, PRKACB, CREB3L2, ATP1B1, PLCB2, ADCY7, ADCY3, GNAS, ATF4, PRKCG, ATF2, ADCY4, GNAQ, PRKCB, TG, CREB1, ADCY6, ADCY8, TSHR, ATF6B, ATP1A3, CGA	1481	65	5892	2.7542720614969096	1.2132295168498786E-10	1.3945511412316591E-12	6.099343252685685E-10
KEGG_PATHWAY	hsa04922:Glucagon signaling pathway	57	3.066164604626143	5.243945337493136E-13	PHKB, ITPR3, CREB3L4, PRKACG, PPP3CA, PLCB3, FOXO1, PYGL, ADCY2, PLCB4, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, CREB3, CREB5, CAMK2A, PRKACA, PPARA, PRKACB, PPP3R1, GYS1, PLCB2, GNAS, PRMT1, CREB1, PDHB, CRTC2, CAMK2G, CAMK2B, CAMK2D, PLCB1, CREBBP, ITPR1, PPP3CB, AKT3, CALML6, PYGM, AKT2, PYGB, CREB3L2, GYS2, PRKAA1, PPP3R2, EP300, ATF4, PPP3CC, ATF2, GNAQ, PCK1, PHKG1, PDE3B, CPT1A, PHKG2, AKT1, PHKA2	1481	93	5892	2.4383698895689485	1.3633316697791997E-10	1.5492052085619434E-12	6.853961842523404E-10
KEGG_PATHWAY	hsa05131:Shigellosis	44	2.366863905325444	5.553639280309407E-13	ITGA5, SRC, CDC42, BTRC, IKBKB, ACTB, MAPK12, WASF2, MAPK10, CHUK, PFN1, CRKL, RHOG, MAPK11, MAPK1, ATG5, MAD2L2, CRK, IKBKG, MAPK13, WASL, FBXW11, ITGB1, NFKBIB, NFKBIA, ARPC1B, ROCK1, RIPK2, MAPK3, ARPC5, NFKB1, ABL1, RAC1, NOD1, ELMO1, WASF1, DOCK1, RELA, ACTG1, MAPK9, MAPK14, CD44, CXCL8, MAPK8	1481	63	5892	2.77856017491399	1.4438672479855086E-10	1.6223689058847413E-12	7.258860179604198E-10
KEGG_PATHWAY	hsa05231:Choline metabolism in cancer	56	3.012372243141474	6.836041637241138E-13	PDGFD, PDGFRA, TSC2, PIK3CG, WASF2, MAPK10, PIK3R1, GRB2, PIK3R3, PDPK1, RAC2, RHEB, MAP2K2, PDGFB, WASL, PRKCB, PDGFA, SOS1, PDGFC, RAC1, TSC1, JUN, PLD1, MAPK9, EGF, SOS2, PIK3R2, MAPK8, RPS6KB1, PRKCA, MAP2K1, AKT3, PIK3CD, AKT2, MAPK1, RAC3, MTOR, FOS, WASF3, PIK3R5, SLC22A1, PRKCG, HIF1A, PLCG1, EIF4EBP1, MAPK3, PLD2, RAF1, WASF1, PIK3CB, PIK3CA, KRAS, SP1, EGFR, NRAS, AKT1	1481	91	5892	2.4482418324416977	1.777267222280443E-10	1.974753693900766E-12	8.934963879880797E-10
KEGG_PATHWAY	hsa05034:Alcoholism	72	3.8730500268961805	2.6815774680284953E-12	GNG4, HDAC2, CREB3L4, GNG10, ARAF, GRIN2A, PPP1CA, CALML5, CALM3, CALML3, CREB3L1, CREB3L3, GRB2, NPY, GRIN2D, CREB3, CREB5, ADCY5, GNAI1, GNB4, SHC1, BRAF, SHC2, HDAC7, GNAS, PPP1CB, GNG13, SOS1, CREB1, HDAC8, HDAC5, SHC3, SHC4, DRD2, SOS2, CRH, FOSB, PPP1CC, GRIN1, HDAC3, MAP2K1, GNG2, ADORA2A, GNAI2, HDAC1, GNG12, CALML6, GNB3, PPP1R1B, GNB2, MAPK1, CREB3L2, H2AFX, GNAI3, GNB5, ATF4, GNG8, ATF2, MAPK3, CAMK4, GNG7, CAMKK2, GNG3, RAF1, ATF6B, GNG5, GNAO1, GRIN2B, KRAS, GNGT1, NRAS, BDNF	1481	134	5892	2.137643988027452	6.972245003566968E-10	7.661760115240668E-12	3.505185031116298E-9
KEGG_PATHWAY	hsa05140:Leishmaniasis	45	2.4206562668101133	5.071457198249731E-12	MYD88, STAT1, IRAK4, ELK1, TLR4, TNF, MAPK12, NCF1, NOS2, TGFB2, MAP3K7, PTPN6, JAK2, IRAK1, MAPK11, IL10, MAPK1, HLA-DMB, ITGAM, FOS, IL12A, TRAF6, MAPK13, IFNG, JAK1, ITGB1, NFKBIB, NFKBIA, PTGS2, MAPK3, NFKB1, HLA-DRB1, TAB1, ITGB2, HLA-DRA, JUN, HLA-DPB1, NCF4, RELA, IL1A, TLR2, MAPK14, TAB2, TGFB1, IL1B	1481	68	5892	2.6327600587838105	1.318589681886806E-9	1.4332535158700921E-11	6.6289973510436084E-9
KEGG_PATHWAY	hsa04724:Glutamatergic synapse	61	3.28133405056482	9.885410578595468E-12	ITPR3, ADCY9, GNG4, GNG10, PRKACG, PPP3CA, PLCB3, GRIA2, GRIA3, GRIN2A, ADCY2, ADCY1, PLCB4, GRIN2D, ADCY5, PRKACA, GNAI1, PRKACB, PPP3R1, GNB4, ADCY7, PLCB2, GNAS, ADCY4, GNG13, PRKCB, GRIA1, PLD1, PLCB1, PRKCA, GRIN1, CACNA1A, ITPR1, GNG2, GNAI2, PPP3CB, GNG12, GNB3, GRIA4, GNB2, MAPK1, GNAI3, GNB5, DLG4, ADCY3, PPP3R2, PPP3CC, PRKCG, CACNA1C, GNAQ, GNG8, MAPK3, PLD2, GNG7, ADCY6, ADCY8, GNG3, GNG5, GNAO1, GRIN2B, GNGT1	1481	108	5892	2.2470552929702152	2.5702107109282224E-9	2.763667072969156E-11	1.2921330672099884E-8
KEGG_PATHWAY	hsa04621:NOD-like receptor signaling pathway	38	2.0441097364174285	2.0002635830366073E-11	CASP1, IKBKB, BIRC3, TNF, MAPK12, MAPK10, IL6, CHUK, MAP3K7, HSP90AA1, BIRC2, HSP90B1, MAPK11, MAPK1, IKBKG, TRAF6, MAPK13, NLRP1, CCL5, CASP8, NFKBIB, CCL2, NFKBIA, SUGT1, RIPK2, MAPK3, NFKB1, TAB1, NLRP3, NOD1, HSP90AB1, MAPK9, RELA, MAPK14, TAB2, CXCL8, IL1B, MAPK8	1481	54	5892	2.799609873208793	5.200693209417295E-9	5.5326521142262663E-11	2.6145663412080467E-8
KEGG_PATHWAY	hsa05014:Amyotrophic lateral sclerosis (ALS)	36	1.9365250134480902	2.7232947080782838E-11	CASP1, MAP2K6, GRIN1, TNF, PPP3CA, MAPK12, GRIA2, GRIN2A, TOMM40, PPP3CB, MAP3K5, GRIN2D, MAPK11, NOS1, MAP2K3, CASP9, MAPK13, PPP3R1, BCL2, PPP3R2, BAD, PPP3CC, NEFL, RAC1, TP53, TNFRSF1A, GRIA1, CYCS, BCL2L1, RAB5A, BAX, CASP3, GRIN2B, BID, MAPK14, TNFRSF1B	1481	50	5892	2.8644429439567856	7.080578345863842E-9	7.453238026755571E-11	3.559649242035334E-8
KEGG_PATHWAY	hsa04150:mTOR signaling pathway	39	2.097902097902098	3.8439228090596884E-11	IGF1, DDIT4, RPS6KB1, PRKCA, RPS6KA2, IKBKB, TSC2, PIK3CG, TNF, RPS6, IRS1, AKT1S1, AKT3, PIK3R1, PIK3CD, PIK3R3, PDPK1, AKT2, MAPK1, RHEB, INS, MTOR, BRAF, PRKAA1, PIK3R5, RPS6KA3, PRKCG, EIF4EBP1, MAPK3, PRKCB, TSC1, EIF4E, RPS6KA1, PIK3CB, RPS6KA6, PIK3CA, PTEN, PIK3R2, AKT1	1481	57	5892	2.7220583531753086	9.994205463215167E-9	1.041062791529157E-10	5.024428650912682E-8
KEGG_PATHWAY	hsa04971:Gastric acid secretion	44	2.366863905325444	5.573852725423277E-11	ITPR3, ADCY9, PRKCA, PLCB1, PRKACG, PLCB3, ITPR1, ADCY1, ADCY2, GNAI2, PLCB4, CFTR, CALML5, CALM3, CALML6, EZR, CALML3, ATP1A2, CAMK2A, ADCY5, PRKACA, ATP1A1, GNAI1, PRKACB, ATP1B1, GNAI3, KCNQ1, PLCB2, ADCY7, KCNE2, ADCY3, GNAS, PRKCG, ADCY4, GNAQ, SLC9A1, PRKCB, ADCY6, ADCY8, MYLK, ATP1A3, CAMK2G, CAMK2B, CAMK2D	1481	69	5892	2.5369462466605994	1.4492016364719973E-8	1.4940226833459747E-10	7.285633207843034E-8
KEGG_PATHWAY	hsa05032:Morphine addiction	49	2.63582571274879	3.2516853823628047E-10	ADCY9, GNG4, PDE4A, PRKCA, GNG10, PRKACG, CACNA1A, KCNJ9, GNG2, ADCY1, ADCY2, GNAI2, GRK4, GNG12, GNB3, KCNJ6, GNB2, ADCY5, PRKACA, OPRM1, GNAI1, PRKACB, GNB4, GNAI3, GNB5, GRK6, ADCY7, ADCY3, GABRG2, GNAS, PRKCG, ADCY4, GNG8, GNG13, PRKCB, GRK5, GNG7, ADCY6, ADCY8, GNG3, GABBR2, ARRB2, PDE3B, GNG5, GNAO1, PDE4B, GABBR1, GNGT1, ARRB1	1481	84	5892	2.3207292370020256	8.454382172118358E-8	8.626921399468301E-10	4.250307439335188E-7
KEGG_PATHWAY	hsa05216:Thyroid cancer	24	1.2910166756320602	3.5242045079947776E-10	TCF7L1, CCND1, TCF7, RXRG, MAP2K1, MAPK3, CTNNB1, TP53, TFG, CDH1, RXRB, PAX8, MAPK1, NTRK1, MYC, LEF1, PPARG, KRAS, MAP2K2, CCDC6, RET, NRAS, TCF7L2, BRAF	1481	28	5892	3.4100511237580786	9.162930658668245E-8	9.255486377313105E-10	4.606519055094793E-7
KEGG_PATHWAY	hsa05202:Transcriptional misregulation in cancer	74	3.9806347498655192	5.456491232610569E-10	LDB1, IGF1, HDAC2, NGFR, MMP9, SMAD1, BCL6, FOXO1, GRIA3, MDM2, RUNX1T1, ITGB7, CDKN1A, CEBPA, ELK4, REL, ZBTB17, TCF3, ETV6, SIN3A, RUNX1, FLT1, SPI1, EWSR1, PDGFA, TP53, IGF1R, BCL2L1, TGFBR2, IL2RB, FUS, DDIT3, RELA, MEN1, PLAU, AFF1, CDKN1B, MLLT1, CSF1R, CCND2, RXRG, MET, NCOR1, IL1R2, CCNT1, CDK9, IL6, IGFBP3, MEIS1, ATM, HDAC1, RARA, RXRB, PAX8, NTRK1, MYC, PPARG, ITGAM, FLT3, ATF1, CD40, JMJD1C, JUP, NFKB1, MEF2C, TFE3, CEBPE, PTK2, MMP3, CEBPB, ZBTB16, SP1, CXCL8, PML	1481	152	5892	1.9368492128362769	1.4186875119115427E-7	1.418687611831615E-9	7.132228141415453E-7
KEGG_PATHWAY	hsa05030:Cocaine addiction	33	1.7751479289940828	6.077057928634152E-10	CREB3L4, GRIN1, PRKACG, GRIA2, GNAI2, GRIN2A, CREB3L1, PPP1R1B, CREB3L3, GRIN2D, CREB3, CREB5, ADCY5, CDK5, PRKACA, CDK5R1, GNAI1, PRKACB, CREB3L2, GNAI3, DLG4, GNAS, ATF4, ATF2, NFKB1, CREB1, JUN, ATF6B, RELA, DRD2, GRIN2B, FOSB, BDNF	1481	47	5892	2.7933397503124686	1.5800348895922411E-7	1.5643910611373713E-9	7.943376734154128E-7
KEGG_PATHWAY	hsa04144:Endocytosis	102	5.486820871436256	1.0680775386975736E-9	TSG101, VPS4B, LDLR, SMURF2, CAV2, CYTH2, CHMP4B, RAB11FIP5, CXCR4, SMAD3, GRK4, HSPA8, MDM2, ITCH, WASL, ARPC5, SNX5, USP8, IL2RB, RHOA, IL2RA, EGF, CAV3, ARRB1, TGFB1, HSPA1L, CHMP2A, CDC42, CBL, TGFB2, ERBB4, RAB5B, CAPZA1, PRKCI, STAM2, FGFR2, CLTC, RAB11B, HSPA6, RET, IST1, LDLRAP1, ASAP1, FGFR3, ARPC1B, STAM, KIF5A, GRK5, PLD2, IQSEC1, SMAD2, ADRB2, EGFR, IL2RG, TGFBR1, SRC, PDGFRA, CAV1, GIT1, HLA-A, HLA-E, TFRC, CBLB, PDCD6IP, FGFR4, SNX4, FLT1, IGF1R, HLA-G, PLD1, KDR, TGFBR2, ARRB2, NEDD4L, F2R, CSF1R, GRK1, MET, CHMP6, ADRB1, HLA-B, SMURF1, GRK7, RNF41, NTRK1, TRAF6, GRK6, HLA-F, ZFYVE27, HSPA2, RAB7A, RAB5C, KIT, RAB5A, CBLC, CCR5, HSPA1A, ARF6, ERBB3, SNF8, PML, PRKCZ	1481	236	5892	1.7194749310475055	2.777001155696013E-7	2.7225505183636756E-9	1.3960937073065338E-6
KEGG_PATHWAY	hsa04530:Tight junction	65	3.4965034965034967	1.219971489763208E-9	PPP2R2D, PPP2R2A, PPP2CB, SRC, RRAS2, PPP2R1B, PPP2R1A, ACTB, CTNNA1, EPB41, PRKCE, PPP2R2C, MRAS, JAM2, PPP2R2B, ACTN4, GNAI1, IGSF5, LLGL2, PRKCB, MYH7, MYH9, MYL12B, MYH10, PPP2CA, RHOA, PTEN, MYL7, PRKCH, CSNK2A2, MYL2, CDC42, MAGI1, PRKCA, CSNK2B, MAGI3, CSNK2A1, CTNNB1, GNAI2, ACTN2, ACTN1, AKT3, MYL12A, PRKCI, AKT2, TJP1, MYL10, GNAI3, JAM3, PRKCG, MYLPF, PRKCD, MPDZ, PRKCQ, MYL5, CTNNA3, MYL9, CDK4, ACTG1, RRAS, KRAS, NRAS, AKT1, F11R, PRKCZ, CTNNA2	1481	129	5892	2.0046166166794905	3.171925287981381E-7	3.0795396233074257E-9	1.594635634649677E-6
KEGG_PATHWAY	hsa04020:Calcium signaling pathway	81	4.357181280258203	1.5778341849967736E-9	PHKB, ITPR3, ADCY9, PTK2B, PDGFRA, PPP3CA, PRKACG, PLCB3, GRIN2A, ADCY1, ADCY2, PLCB4, CALML5, CALM3, CALML3, GRIN2D, PLCG2, CAMK2A, CHRM2, PRKACA, PRKACB, PPP3R1, GNA11, ADCY7, PLCB2, GNAS, ATP2B4, ORAI1, HTR7, ADCY4, PRKCB, RYR2, CAMK2G, CAMK2B, BDKRB1, F2R, CAMK2D, VDAC3, PLCB1, PRKCA, GRIN1, GNA15, VDAC2, NOS2, CACNA1A, ADRB1, ERBB4, ITPR1, ATP2A2, ADORA2A, PPP3CB, SLC25A5, CALML6, NOS3, ERBB2, NOS1, GNAL, STIM1, ADCY3, PLCE1, PPP3R2, PLN, PPP3CC, PRKCG, GNAQ, CACNA1C, PLCG1, AGTR1, CAMK4, ATP2A3, BDKRB2, SLC25A4, ADCY8, ADRB2, PHKG1, MYLK, SLC8A1, PHKG2, ERBB3, EGFR, PHKA2	1481	175	5892	1.8414276068293625	4.1023680730223333E-7	3.944585436066461E-9	2.062401238678291E-6
KEGG_PATHWAY	hsa04115:p53 signaling pathway	40	2.151694459386767	2.186013935037938E-9	CCNB2, CCND1, MDM4, IGF1, CCND2, CCNE2, GADD45B, BBC3, SFN, TSC2, CDKN2A, CDK1, RRM2, IGFBP3, ATM, MDM2, CDKN1A, CDK6, PMAIP1, CCND3, THBS1, CASP9, CHEK1, CASP8, CCNE1, CHEK2, SESN2, CDK2, TP53, CYCS, CCNB1, ATR, BAX, CDK4, FAS, CCNG1, CASP3, TP73, PTEN, BID	1481	65	5892	2.4482418324416977	5.683634597408727E-7	5.412986836539346E-9	2.8573584054392143E-6
KEGG_PATHWAY	hsa04911:Insulin secretion	48	2.5820333512641205	2.2240841099597526E-9	ITPR3, ADCY9, PRKCA, CREB3L4, PLCB1, PRKACG, PLCB3, ADCY1, ADCY2, PLCB4, STX1A, ADCYAP1R1, CREB3L1, CREB3L3, ATP1A2, CREB3, CREB5, CAMK2A, FXYD2, ADCY5, INS, PRKACA, ATP1A1, PRKACB, CREB3L2, ATP1B1, GNA11, VAMP2, PLCB2, ADCY7, ADCY3, GNAS, ATF4, PRKCG, ATF2, ADCY4, CACNA1C, GNAQ, PRKCB, RYR2, CREB1, ADCY6, ADCY8, ATF6B, ATP1A3, CAMK2G, CAMK2B, CAMK2D	1481	85	5892	2.2466219168288517	5.782617096272702E-7	5.4553006556545824E-9	2.907120322248602E-6
KEGG_PATHWAY	hsa04270:Vascular smooth muscle contraction	58	3.1199569661108124	2.9673194273139375E-9	ITPR3, ADCY9, PRKACG, PLCB3, ARAF, ADCY1, ADCY2, PPP1R14A, PLCB4, PPP1CA, PRKCE, CALML5, CALM3, CALML3, ADCY5, PRKACA, MAP2K2, PRKACB, GNA11, BRAF, ADCY7, PLCB2, GNAS, PPP1CB, ROCK1, ADCY4, PRKCB, GNA13, RHOA, PRKCH, PLA2G2A, ARHGEF1, PPP1CC, PRKCA, PLCB1, MAP2K1, ITPR1, ADORA2A, ARHGEF12, NPR1, CALML6, MAPK1, ADCY3, PRKCG, CACNA1C, GNAQ, MAPK3, PLA2G10, PRKCD, PRKG1, AGTR1, ADCY6, ADCY8, RAF1, PRKCQ, MYLK, MYL9, ACTG2	1481	112	5892	2.060239220603839	7.715027450228007E-7	7.210308794469711E-9	3.8786097666942965E-6
KEGG_PATHWAY	hsa04726:Serotonergic synapse	54	2.9047875201721354	4.155167096648938E-9	ITPR3, GNG4, GNG10, PRKACG, PLCB3, ARAF, HTR1E, PLCB4, ADCY5, PRKACA, GNAI1, PRKACB, GNB4, BRAF, PLCB2, GNAS, PTGS2, HTR7, GNG13, PRKCB, PRKCA, PLCB1, MAP2K1, KCNJ9, CACNA1A, ITPR1, GNG2, GNAI2, GNG12, GNB3, KCNJ6, GNB2, MAPK1, HTR1F, GNAI3, HTR1D, GNB5, HTR1B, PRKCG, GNG8, CACNA1C, GNAQ, MAPK3, APP, GNG7, GNG3, RAF1, HTR1A, GNG5, GNAO1, CASP3, KRAS, GNGT1, NRAS	1481	102	5892	2.1062080470270486	1.0803428645012048E-6	1.0003180062057027E-8	5.431256111521066E-6
KEGG_PATHWAY	hsa05120:Epithelial cell signaling in Helicobacter pylori infection	39	2.097902097902098	5.337433477440716E-9	SRC, CDC42, MAP3K14, IKBKB, MET, CSK, MAPK12, MAPK10, CHUK, ATP6V0A1, PLCG2, PTPN11, MAPK11, JAM2, GIT1, IKBKG, MAPK13, LYN, TJP1, CCL5, IGSF5, PAK1, NFKBIA, JAM3, PLCG1, NFKB1, RAC1, ADAM17, NOD1, JUN, RELA, MAPK9, MAP2K4, CASP3, MAPK14, EGFR, CXCL8, F11R, MAPK8	1481	64	5892	2.4243332207967594	1.3877317495136765E-6	1.273149274894081E-8	6.97660704762626E-6
KEGG_PATHWAY	hsa04960:Aldosterone-regulated sodium reabsorption	28	1.506186121570737	7.839506220893862E-9	IGF1, PRKCA, SFN, PIK3CG, IRS1, PIK3R1, PIK3CD, ATP1A2, PDPK1, PIK3R3, MAPK1, FXYD2, INS, INSR, ATP1A1, ATP1B1, PIK3R5, PRKCG, MAPK3, PRKCB, PIK3CB, NEDD4L, ATP1A3, NR3C2, PIK3CA, PIK3R2, KRAS, SCNN1G	1481	39	5892	2.856282137848647	2.038269560022954E-6	1.8529741963035917E-8	1.0247088588766218E-5
KEGG_PATHWAY	hsa05230:Central carbon metabolism in cancer	37	1.9903173749327596	1.6983006426062035E-8	SLC16A3, PFKP, MET, PDGFRA, PIK3CG, MAP2K1, PFKL, AKT3, PIK3R1, PIK3CD, PIK3R3, ERBB2, AKT2, MAPK1, FGFR2, NTRK1, MYC, MTOR, MAP2K2, RET, FLT3, PIK3R5, FGFR3, HIF1A, MAPK3, TP53, KIT, RAF1, PDHB, PIK3CB, PIK3CA, PTEN, KRAS, PIK3R2, EGFR, NRAS, AKT1	1481	61	5892	2.4131236094353614	4.415571964733189E-6	3.978001461568681E-8	2.2198638027770556E-5
KEGG_PATHWAY	hsa04924:Renin secretion	36	1.9365250134480902	2.2323103208648085E-8	ITPR3, PRKG2, PLCB1, PRKACG, PPP3CA, PLCB3, ADRB1, ITPR1, GNAI2, PLCB4, PPP3CB, NPR1, CALML5, ADCYAP1R1, CALM3, CALML6, CALML3, ADCY5, PRKACA, GNAI1, PRKACB, PPP3R1, GNAI3, PLCB2, GNAS, PPP3R2, ORAI1, PPP3CC, CTSB, CACNA1C, GNAQ, AGTR1, CREB1, ADCY6, ADRB2, PDE3B	1481	59	5892	2.4274940203023605	5.803990067776432E-6	5.1821488988856856E-8	2.917872488072959E-5
KEGG_PATHWAY	hsa04612:Antigen processing and presentation	38	2.0441097364174285	2.3250884601608817E-8	HSPA4, HSPA1L, CD4, CALR, KIR3DL2, TNF, TAP1, HLA-B, HSPA8, HSP90AA1, HLA-DMB, HLA-A, HLA-E, RFX5, HSPA6, CTSS, RFXANK, KIR3DL1, IFNG, CIITA, PDIA3, KIR2DL2, HLA-F, CTSB, PSME1, HSPA2, KIR2DL4, HLA-DRB1, NFYB, KIR2DL5A, CREB1, HLA-G, HLA-DRA, CD74, HLA-DPB1, HSP90AB1, HSPA1A, NFYA	1481	64	5892	2.362170830519919	6.045211781158244E-6	5.349760967554573E-8	3.0391435812404666E-5
KEGG_PATHWAY	hsa04350:TGF-beta signaling pathway	44	2.366863905325444	3.3472839397340684E-8	TGFBR1, E2F4, PPP2CB, SMURF2, RPS6KB1, PPP2R1B, PPP2R1A, TNF, ID3, CREBBP, SMAD1, TGFB2, SMAD3, SMAD5, CDKN2B, INHBB, SMURF1, SMAD7, ACVR1, SKP1, RBX1, MAPK1, CUL1, RBL1, MYC, BMPR2, THBS1, SMAD9, IFNG, INHBA, EP300, ROCK1, MAPK3, SMAD6, DCN, SMAD2, TGFBR2, SMAD4, PPP2CA, RHOA, LTBP1, TFDP1, SP1, TGFB1	1481	80	5892	2.188116137744767	8.70290051635525E-6	7.634156184987972E-8	4.375264024414349E-5
KEGG_PATHWAY	hsa05132:Salmonella infection	44	2.366863905325444	3.3472839397340684E-8	CASP1, CXCL1, MYD88, CDC42, ACTB, TLR4, MAPK12, WASF2, MAPK10, NOS2, IL6, PFN1, RHOG, MAPK11, MAPK1, CXCL2, FOS, MAPK13, TJP1, WASL, IFNG, ARPC1B, ROCK1, FLNA, CCL4, MAPK3, ARPC5, NFKB1, RAB7A, FLNB, RAC1, FLNC, JUN, WASF1, IL1A, RELA, ACTG1, MAPK9, PKN1, CCL3, MAPK14, CXCL8, MAPK8, IL1B	1481	80	5892	2.188116137744767	8.70290051635525E-6	7.634156184987972E-8	4.375264024414349E-5
KEGG_PATHWAY	hsa04930:Type II diabetes mellitus	31	1.6675632060247445	4.292951733092262E-8	IKBKB, PIK3CG, TNF, CACNA1A, MAPK10, IRS1, SOCS1, PRKCE, PIK3R1, PIK3CD, SOCS4, PIK3R3, MAPK1, IRS4, INS, INSR, MTOR, PIK3R5, CACNA1C, MAPK3, PRKCD, IRS2, SLC2A4, PIK3CB, PIK3CA, MAPK9, PIK3R2, SOCS2, SOCS3, PRKCZ, MAPK8	1481	48	5892	2.5693787981093856	1.1161612468502113E-5	9.705803671877788E-8	5.6113543311919756E-5
KEGG_PATHWAY	hsa04970:Salivary secretion	41	2.205486820871436	1.3408521070460006E-7	ITPR3, ADCY9, PRKG2, PRKCA, PLCB1, PRKACG, PLCB3, ADRB1, ITPR1, ADCY2, ADCY1, PLCB4, CALML5, CALM3, CALML6, CALML3, ATP1A2, SLC12A2, NOS1, FXYD2, ADCY5, PRKACA, ATP1A1, PRKACB, ATP1B1, VAMP2, PLCB2, ADCY7, ADCY3, GNAS, ATP2B4, PRKCG, ADCY4, GNAQ, SLC9A1, PRKCB, PRKG1, ADCY6, ADCY8, ADRB2, ATP1A3	1481	75	5892	2.174854827819041	3.486154944454256E-5	3.005357921415097E-7	1.7526384170629683E-4
KEGG_PATHWAY	hsa04727:GABAergic synapse	44	2.366863905325444	1.3685592556541428E-7	ADCY9, GNG4, SRC, PRKCA, GNG10, PRKACG, GABARAPL2, CACNA1A, GNG2, ADCY1, ADCY2, GNAI2, GNG12, GNB3, KCNJ6, GABARAPL1, GNB2, ADCY5, PRKACA, GABARAP, GNAI1, PRKACB, GNB4, GNAI3, GNB5, ADCY7, ADCY3, GABRG2, NSF, PRKCG, ADCY4, CACNA1C, GNG8, GNG13, PRKCB, GNG7, ADCY6, ADCY8, GNG3, GABBR2, GNG5, GNAO1, GABBR1, GNGT1	1481	83	5892	2.1090276026455586	3.558191003760758E-5	3.041242536694355E-7	1.7888546208766343E-4
KEGG_PATHWAY	hsa04360:Axon guidance	57	3.066164604626143	1.9825102924694183E-7	PPP3CA, CXCR4, PLXNB2, CFL1, SLIT2, NFATC2, RGS3, RAC2, LIMK1, CDK5, PAK3, GNAI1, PPP3R1, ITGB1, PAK1, GSK3B, ROBO1, ROCK1, ABL1, RAC1, CXCL12, RND1, RHOA, LIMK2, FES, CDC42, MET, EFNA1, PAK6, ARHGEF12, GNAI2, DPYSL2, PPP3CB, SEMA4F, MAPK1, RAC3, FYN, PLXNA3, NFATC3, EPHB2, GNAI3, PPP3R2, PAK4, PPP3CC, MAPK3, PAK2, SRGAP2, PLXNA2, SRGAP3, PTK2, NFATC4, SLIT1, EFNA4, NCK1, KRAS, NRAS, EFNA5	1481	120	5892	1.8897366644159352	5.154394428219522E-5	4.368242496610719E-7	2.591353913561356E-4
KEGG_PATHWAY	hsa05144:Malaria	29	1.5599784830554062	2.72807541083142E-7	THBS2, MYD88, MET, TLR4, TNF, SELE, IL6, TGFB2, GYPC, HGF, IL10, SELP, THBS1, IL12A, SDC2, IFNG, VCAM1, SDC1, HBA1, CD40, CCL2, ITGB2, TLR9, LRP1, ITGAL, TLR2, CXCL8, TGFB1, IL1B	1481	46	5892	2.5081173120394564	7.092745489356567E-5	5.9604999347318E-7	3.5658860073617404E-4
KEGG_PATHWAY	hsa05134:Legionellosis	31	1.6675632060247445	2.970262593244555E-7	CASP1, CXCL1, MYD88, HSPA1L, TNF, TLR4, IL6, HSPA8, NFKB2, HSF1, CXCL2, ITGAM, CASP7, IL12A, HSPA6, CASP9, EEF1A1, CASP8, NFKBIA, HSPA2, NFKB1, ITGB2, CYCS, EEF1G, HSPD1, HSPA1A, RELA, CASP3, TLR2, CXCL8, IL1B	1481	51	5892	2.4182388688088334	7.722385698882839E-5	6.435567837526079E-7	3.8824499607459373E-4
KEGG_PATHWAY	hsa04932:Non-alcoholic fatty liver disease (NAFLD)	63	3.388918773534158	3.3600612322078816E-7	PIK3CG, MAPK10, IRS1, UQCR10, PIK3R1, SREBF1, PIK3R3, MAP3K5, XBP1, INS, INSR, PPARA, CASP7, CEBPA, ITCH, ERN1, UQCRFS1, BCL2L11, CYC1, CASP8, GSK3B, MAP3K11, RAC1, FASLG, TNFRSF1A, JUN, BAX, DDIT3, RELA, MAPK9, PIK3R2, BID, TGFB1, SOCS3, IL1B, MAPK8, CDC42, IKBKB, TNF, IL6, AKT3, PIK3CD, AKT2, GSK3A, PRKAA1, NDUFV1, NDUFS3, ATF4, PIK3R5, NFKB1, TRAF2, CYCS, IRS2, UQCRC1, PIK3CB, EIF2AK3, PIK3CA, IL1A, FAS, CASP3, EIF2S1, CXCL8, AKT1	1481	139	5892	1.8031565294692	8.735779081014972E-5	7.219964891502784E-7	4.39195731694042E-4
KEGG_PATHWAY	hsa05321:Inflammatory bowel disease (IBD)	35	1.8827326519634213	4.925357787410929E-7	IL21R, IL2RG, IL21, STAT1, TLR4, TNF, IL6, SMAD3, TGFB2, IL17A, STAT6, IL12RB2, NFATC1, IL10, HLA-DMB, IL12A, FOXP3, IFNG, IL4R, NFKB1, HLA-DRB1, IL5, IL2, HLA-DRA, JUN, HLA-DPB1, SMAD2, IL12RB1, RELA, STAT4, IL1A, TLR2, STAT3, TGFB1, IL1B	1481	62	5892	2.2458670035503476	1.2805113475700125E-4	1.0496661212444636E-6	6.437960274552346E-4
KEGG_PATHWAY	hsa04920:Adipocytokine signaling pathway	38	2.0441097364174285	5.34007930224885E-7	RXRG, IKBKB, TNF, MAPK10, IRS1, POMC, CHUK, AKT3, JAK2, NPY, RXRB, PTPN11, AKT2, IRS4, MTOR, PPARA, NFKBIE, IKBKG, PRKAA1, NFKBIB, NFKBIA, PCK1, NFKB1, TRAF2, CAMKK2, IRS2, TNFRSF1A, SLC2A4, PRKCQ, CPT1A, TRADD, RELA, MAPK9, TNFRSF1B, SOCS3, AKT1, STAT3, MAPK8	1481	70	5892	2.159699045046783	1.388324608074809E-4	1.1287969151618782E-6	6.980043133930636E-4
KEGG_PATHWAY	hsa04140:Regulation of autophagy	25	1.3448090371167294	7.497390596585387E-7	IFNA10, IFNA21, ATG16L1, IFNA5, IFNA1, GABARAPL2, ATG12, GABARAPL1, ATG3, ATG7, IFNA14, ATG5, INS, IFNA17, GABARAP, PRKAA1, IFNG, BECN1, ATG10, PIK3C3, ATG16L2, IFNA4, IFNA16, IFNA8, IFNA6	1481	38	5892	2.617363801130104	1.94913230521232E-4	1.5720328657709004E-6	9.799862259129988E-4
KEGG_PATHWAY	hsa05143:African trypanosomiasis	22	1.183431952662722	1.4950172994150013E-6	IFNG, VCAM1, PLCB2, MYD88, HBA1, PRKCA, PLCB1, PRKCG, TNF, GNAQ, PLCB3, SELE, PRKCB, IL6, TLR9, PLCB4, FASLG, IL10, FAS, APOA1, IL12A, IL1B	1481	32	5892	2.735145172180959	3.8862925248595026E-4	3.1096334722757746E-6	0.001954132910542139
KEGG_PATHWAY	hsa05010:Alzheimer's disease	62	3.335126412049489	1.5001639113179625E-6	ITPR3, GAPDH, SNCA, PPP3CA, PLCB3, PSEN2, GRIN2A, PLCB4, UQCR10, CALML5, CALM3, CALML3, GRIN2D, CDK5, CDK5R1, CASP7, CASP9, PPP3R1, ERN1, UQCRFS1, PLCB2, MME, CYC1, CASP8, BAD, GSK3B, ADAM17, TNFRSF1A, LRP1, APOE, BID, BACE1, IL1B, PSEN1, PLCB1, GRIN1, TNF, ITPR1, ATP2A2, PPP3CB, CALML6, FADD, NOS1, MAPK1, MAPT, PPP3R2, NDUFV1, NDUFS3, PPP3CC, CACNA1C, GNAQ, MAPK3, CAPN1, APP, ATP2A3, CYCS, UQCRC1, EIF2AK3, FAS, CASP3, GRIN2B, ATF6	1481	141	5892	1.7493642880744755	3.8996685265968445E-4	3.0955738555826784E-6	0.001960859971594786
KEGG_PATHWAY	hsa04623:Cytosolic DNA-sensing pathway	32	1.7213555675094134	2.001512113689715E-6	IFNA10, CASP1, TBK1, IFNA21, IFNA5, IFNA1, ZBP1, IKBKB, IKBKE, IRF7, IL6, CHUK, RIPK1, IFNA14, TMEM173, IFNA17, IKBKG, CCL5, NFKBIB, NFKBIA, IFNB1, CCL4, NFKB1, MAVS, IRF3, DDX58, RELA, IFNA4, IFNA16, IFNA6, IFNA8, IL1B	1481	57	5892	2.233483776964356	5.202582890517782E-4	4.097579560435882E-6	0.002616162861368565
KEGG_PATHWAY	hsa05020:Prion diseases	22	1.183431952662722	3.1421946217032775E-6	CCL5, C8B, C9, ELK1, PRKACG, STIP1, NCAM1, MAP2K1, MAPK3, IL6, EGR1, PRNP, BAX, IL1A, MAPK1, FYN, HSPA5, LAMC1, PRKACA, MAP2K2, PRKACB, IL1B	1481	33	5892	2.6522619851451723	8.166382545211626E-4	6.382572484309179E-6	0.004107112928009027
KEGG_PATHWAY	hsa05320:Autoimmune thyroid disease	28	1.506186121570737	6.606090965933528E-6	IFNA10, IFNA21, IFNA5, IFNA1, HLA-B, IFNA14, IL10, HLA-DMB, IFNA17, HLA-E, HLA-A, HLA-F, CD40, HLA-DRB1, TG, FASLG, IL5, HLA-DRA, HLA-G, IL2, HLA-DPB1, TSHR, FAS, CGA, IFNA4, IFNA16, IFNA6, IFNA8	1481	49	5892	2.273367415838719	0.0017161151120290707	1.3314557286259188E-5	0.008634536574358975
KEGG_PATHWAY	hsa04972:Pancreatic secretion	39	2.097902097902098	1.5647451581766787E-5	PLA2G2A, ITPR3, ADCY9, PRKCA, PLCB1, PLCB3, ITPR1, ATP2A2, ADCY2, ADCY1, PLCB4, CFTR, ATP1A2, SLC12A2, FXYD2, ADCY5, ATP1A1, ATP1B1, RAP1A, RAP1B, KCNQ1, PLCB2, ADCY7, ADCY3, GNAS, ATP2B4, PRKCG, GNAQ, ADCY4, SLC9A1, PRKCB, PLA2G10, ATP2A3, RYR2, RAC1, ADCY6, ADCY8, ATP1A3, RHOA	1481	81	5892	1.915522544827069	0.004060104638626827	3.1294658320857316E-5	0.020450993057574696
KEGG_PATHWAY	hsa05416:Viral myocarditis	29	1.5599784830554062	2.076154613592166E-5	CCND1, ACTB, HLA-B, CAV1, RAC2, HLA-DMB, FYN, RAC3, HLA-A, HLA-E, DAG1, CASP9, HLA-F, CD40, CASP8, EIF4G1, HLA-DRB1, ABL1, MYH7, ITGB2, RAC1, CYCS, HLA-G, HLA-DRA, HLA-DPB1, ITGAL, ACTG1, CASP3, BID	1481	54	5892	2.1365443769224997	0.005383514696656322	4.120570088095299E-5	0.027134203197354267
KEGG_PATHWAY	hsa04640:Hematopoietic cell lineage	38	2.0441097364174285	2.1165779487836346E-5	IL9R, KITLG, CD59, ITGA5, CSF1R, CD4, IL7R, IL1R2, IL11, TNF, IL6, ITGA3, IL1R1, ITGA2, CSF3R, ITGAM, IL4R, FLT3, MME, TFRC, CD2, HLA-DRB1, ITGB3, KIT, IL5, HLA-DRA, CSF1, EPOR, ITGA1, IL5RA, IL3RA, IL1A, IL2RA, ITGA6, CD44, CD3E, GP1BA, IL1B	1481	79	5892	1.913657381687023	0.005488046255241019	4.16897438857422E-5	0.02766244655070249
KEGG_PATHWAY	hsa05130:Pathogenic Escherichia coli infection	27	1.4523937600860677	2.408810966474352E-5	TUBB4A, TUBB, CDC42, TUBA1A, PRKCA, ACTB, TLR4, CTNNB1, TUBB4B, CDH1, EZR, TUBA4A, TUBA1C, FYN, WASL, TUBB3, ARHGEF2, ITGB1, ARPC1B, ROCK1, ARPC5, ABL1, RHOA, ACTG1, TUBB2A, NCK1, NCL	1481	49	5892	2.1921757224159073	0.006243412341096044	4.7088996126931626E-5	0.031481207399541855
KEGG_PATHWAY	hsa05217:Basal cell carcinoma	29	1.5599784830554062	3.2268252519654834E-5	WNT3A, TCF7L1, FZD6, FZD4, TCF7, GLI3, GSK3B, GLI2, AXIN1, SUFU, WNT10A, AXIN2, WNT5B, CTNNB1, FZD10, DVL3, TP53, FZD2, FZD5, APC, DVL2, WNT1, DVL1, FZD7, LEF1, FZD9, GLI1, FZD8, TCF7L2	1481	55	5892	2.097698115523909	0.008354784188813857	6.260909235134005E-5	0.04216990928013198
KEGG_PATHWAY	hsa04320:Dorso-ventral axis formation	15	0.8068854222700376	6.972646566187382E-5	ETV6, ETS1, MAPK3, MAP2K1, SOS1, NOTCH1, NOTCH2, GRB2, NOTCH4, MAPK1, ETS2, SOS2, KRAS, EGFR, NOTCH3	1481	21	5892	2.8417092697983986	0.017966162157114995	1.3428367301338007E-4	0.0911017444122475
KEGG_PATHWAY	hsa04120:Ubiquitin mediated proteolysis	53	2.850995158687466	1.448158565958784E-4	BIRC6, ANAPC1, SMURF2, CDC16, CDC20, CUL5, SOCS1, UBE2D3, MDM2, PIAS3, UBE4A, CUL1, CDC27, CUL3, ITCH, FBXW11, ANAPC10, ANAPC11, PIAS2, FZR1, UBE2L3, UBE2B, CBLB, PIAS4, UBE2J2, NEDD4L, UBE2H, SOCS3, PIAS1, ANAPC5, ANAPC4, ANAPC2, UBE2D2, BTRC, CBL, PRPF19, BIRC3, SMURF1, BIRC2, TRIM37, BRCA1, SKP1, RBX1, UBE2I, TRAF6, CDC26, MAP3K1, HUWE1, UBE2K, UBE2W, CBLC, STUB1, PML	1481	131	5892	1.6095788383132914	0.036954720703958666	2.768355658021582E-4	0.18912474794384737
KEGG_PATHWAY	hsa04961:Endocrine and other factor-regulated calcium reabsorption	24	1.2910166756320602	1.5058916509620745E-4	PLCB2, ADCY9, GNAS, PRKCA, PLCB1, VDR, PRKCG, PRKACG, GNAQ, PLCB3, PRKCB, BDKRB2, PLCB4, ADCY6, ESR1, ATP1A2, ATP1A3, FXYD2, CLTC, TRPV5, PRKACA, ATP1A1, PRKACB, ATP1B1	1481	45	5892	2.121809588116138	0.03839943846619642	2.8577033683696573E-4	0.19665764774431382
KEGG_PATHWAY	hsa05414:Dilated cardiomyopathy	37	1.9903173749327596	1.969827559308709E-4	IGF1, ITGA5, ADCY9, MYL2, ACTB, PRKACG, TNF, ADRB1, TGFB2, ADCY1, ADCY2, ITGA3, ITGB8, ITGAV, ITGA2, ITGB7, ACTC1, ADCY5, PRKACA, EMD, DAG1, PRKACB, ADCY7, ADCY3, GNAS, ITGB1, PLN, ADCY4, CACNA1C, ITGB3, RYR2, ADCY6, ADCY8, ITGA1, ACTG1, ITGA6, TGFB1	1481	83	5892	1.773500484042856	0.04993090123575017	3.710946164211526E-4	0.2571720373121811
KEGG_PATHWAY	hsa04512:ECM-receptor interaction	38	2.0441097364174285	2.614968493685478E-4	COL4A3, FN1, THBS2, ITGA5, SPP1, COL4A5, RELN, COL4A1, ITGA3, TNXB, ITGB8, ITGAV, ITGA2, COL2A1, ITGB7, LAMC1, THBS1, DAG1, HSPG2, SDC1, COL6A3, ITGB1, COL4A2, COL1A1, LAMA1, ITGB3, COL1A2, COL4A6, LAMA5, ITGA1, TNR, VTN, VWF, SDC4, ITGA6, IBSP, CD44, GP1BA	1481	87	5892	1.7376888868192508	0.06573772503993225	4.890751253644465E-4	0.34126593890083656
KEGG_PATHWAY	hsa05340:Primary immunodeficiency	19	1.0220548682087143	2.764771788830215E-4	IL2RG, CIITA, LCK, CD40, PTPRC, ORAI1, CD4, IL7R, TAP1, BTK, RAG1, BLNK, UNG, ZAP70, RFX5, IKBKG, ADA, CD3E, RFXANK	1481	33	5892	2.2905898962617397	0.06937046779836198	5.133967774186843E-4	0.36078337819834827
KEGG_PATHWAY	hsa04962:Vasopressin-regulated water reabsorption	22	1.183431952662722	4.2867548157738756E-4	VAMP2, ADCY3, ADCY9, GNAS, NSF, ARHGDIA, CREB3L4, PRKACG, RAB5B, CREB1, RAB5C, ADCY6, RAB5A, CREB3L1, CREB3L3, CREB3, DCTN1, CREB5, RAB11B, PRKACA, PRKACB, CREB3L2	1481	42	5892	2.0839201311854922	0.1054902902866588	7.903224326119007E-4	0.5588781392949826
KEGG_PATHWAY	hsa05323:Rheumatoid arthritis	35	1.8827326519634213	7.980965423394584E-4	TNFRSF11A, IL11, TNFSF11, TLR4, TNF, IL6, TGFB2, IL17A, ATP6V0A1, TNFSF13, HLA-DMB, CXCL5, FOS, ANGPT1, IFNG, CCL5, CCL2, FLT1, HLA-DRB1, ITGB2, HLA-DRA, JUN, CSF1, HLA-DPB1, CXCL12, MMP3, ITGAL, IL1A, VEGFA, TLR2, CCL3, CXCL8, TGFB1, MMP1, IL1B	1481	82	5892	1.6980945636600189	0.18745822412932123	0.0014608189330798105	1.0381888953063578
KEGG_PATHWAY	hsa05332:Graft-versus-host disease	17	0.914470145239376	0.0013350215426657665	IFNG, HLA-F, TNF, HLA-DRB1, IL6, HLA-B, FASLG, IL2, HLA-G, HLA-DRA, HLA-DPB1, IL1A, HLA-DMB, FAS, HLA-A, HLA-E, IL1B	1481	31	5892	2.1816993748774802	0.29343318128664686	0.0024259861237696523	1.7310270608945189
KEGG_PATHWAY	hsa04913:Ovarian steroidogenesis	23	1.237224314147391	0.0014076112724093746	ADCY7, IGF1, ADCY3, ADCY9, GNAS, FSHB, LDLR, PTGS2, PRKACG, ADCY4, ADCY2, ADCY1, ADCY6, ADCY8, IGF1R, CYP19A1, FSHR, ADCY5, INS, CGA, INSR, PRKACA, PRKACB	1481	48	5892	1.9063133018230927	0.3066613667193544	0.0025400792949412665	1.8243509993293716
KEGG_PATHWAY	hsa05330:Allograft rejection	18	0.9682625067240451	0.002241245385051378	IFNG, CD40, HLA-F, TNF, HLA-DRB1, HLA-B, IL5, FASLG, IL2, HLA-G, HLA-DRA, HLA-DPB1, IL10, HLA-DMB, FAS, HLA-A, HLA-E, IL12A	1481	35	5892	2.046030674254847	0.4419896626074308	0.004015212501636611	2.8902494517486055
KEGG_PATHWAY	hsa05412:Arrhythmogenic right ventricular cardiomyopathy (ARVC)	29	1.5599784830554062	0.004169097975502774	ITGA5, TCF7, CDH2, ACTB, CTNNA1, CTNNB1, ACTN2, ITGA3, ACTN1, ITGB8, ITGAV, ITGA2, ITGB7, ACTN4, LEF1, EMD, DAG1, TCF7L2, TCF7L1, ITGB1, CACNA1C, JUP, ITGB3, RYR2, CTNNA3, ITGA1, ACTG1, ITGA6, CTNNA2	1481	70	5892	1.6481913764830711	0.6625140343305382	0.007412332922167031	5.314429465484949
KEGG_PATHWAY	hsa04940:Type I diabetes mellitus	19	1.0220548682087143	0.004774328521074929	IFNG, HLA-F, TNF, HLA-DRB1, HLA-B, FASLG, IL2, HLA-G, HLA-DRA, HLA-DPB1, HSPD1, IL1A, HLA-DMB, FAS, INS, HLA-A, HLA-E, IL12A, IL1B	1481	40	5892	1.8897366644159352	0.7118569234778542	0.008428889150543517	6.063872136607118
KEGG_PATHWAY	hsa04141:Protein processing in endoplasmic reticulum	54	2.9047875201721354	0.004902252308603345	NFE2L2, MAPK10, HSPBP1, UBE2D3, HSPA8, MAP3K5, EIF2AK1, XBP1, EIF2AK4, CUL1, BCAP31, BCL2, ERN1, UBE2J2, RAD23B, PRKCSH, HSP90AB1, RRBP1, BAX, RAD23A, DDIT3, MAPK9, P4HB, MAPK8, UBE2D2, HSPA1L, CALR, DNAJB1, PDIA4, HSP90AA1, HSP90B1, SKP1, RBX1, HSPA5, BAG1, DNAJC3, HSPA6, PDIA3, UBQLN4, ATF4, EIF2AK2, HSPA2, CAPN1, TRAF2, BAK1, PDIA6, ATF6B, EIF2AK3, HSPA1A, EIF2S1, ATF6, MAP2K7, STUB1, HSPH1	1481	153	5892	1.4041386980180324	0.7213280563882031	0.008596083934001908	6.2215741723120725
KEGG_PATHWAY	hsa04340:Hedgehog signaling pathway	14	0.7530930607853685	0.005347050642042873	FBXW11, GLI3, GLI2, GSK3B, BTRC, PRKACG, SUFU, CSNK1A1, CSNK1D, CSNK1E, PRKACA, GLI1, PRKACB, CSNK1G2	1481	26	5892	2.1422116033864853	0.7519099002194014	0.009311832196944758	6.7680121151939225
KEGG_PATHWAY	hsa04710:Circadian rhythm	15	0.8068854222700376	0.008394650744558696	FBXW11, PRKAA1, BTRC, CSNK1D, PER1, CREB1, CLOCK, ARNTL, PER2, SKP1, RBX1, CSNK1E, CUL1, PER3, CRY1	1481	30	5892	1.9891964888588791	0.8882869678941895	0.01450590674546326	10.433640524886789
KEGG_PATHWAY	hsa04145:Phagosome	49	2.63582571274879	0.013652816113016206	TUBB4A, THBS2, TUBB, ITGA5, TUBA1A, CALR, ACTB, TLR4, SFTPD, TAP1, NCF1, RAB5B, HLA-B, TUBB4B, ATP6V0A1, MRC1, ITGAV, ITGA2, TUBA4A, NOS1, PLA2R1, TUBA1C, HLA-DMB, ITGAM, HLA-A, HLA-E, THBS1, CTSS, TUBB3, HLA-F, ITGB1, TFRC, HLA-DRB1, CD209, RAB7A, ITGB2, ITGB3, RAB5C, RAC1, HLA-DRA, HLA-G, HLA-DPB1, RAB5A, NCF4, PIK3C3, ACTG1, TUBB2A, CLEC4M, TLR2	1481	143	5892	1.3632255657913996	0.9719617869970817	0.023392172413475687	16.44679826066455
KEGG_PATHWAY	hsa03015:mRNA surveillance pathway	31	1.6675632060247445	0.019217274068025418	RNPS1, PPP2R2D, PPP2R2A, PPP2CB, PPP1CC, UPF2, PPP2R1B, PPP2R1A, PPP1CA, PPP2R2C, FIP1L1, PPP2R5C, PPP2R3C, CPSF7, PNN, PPP2R2B, PPP2R5D, CPSF2, UPF1, PABPN1, WDR82, PPP2R5A, PPP1CB, PABPC4, SRRM1, PPP2R3A, PAPOLA, DAZAP1, PPP2R5B, PPP2CA, PPP2R5E	1481	84	5892	1.468216456062506	0.9935593435206698	0.03264681326329122	22.402555477234422
KEGG_PATHWAY	hsa04976:Bile secretion	24	1.2910166756320602	0.023883357185582405	NR0B2, ADCY7, ADCY3, ADCY9, GNAS, SLC22A1, LDLR, PRKACG, ADCY4, SLC9A1, ADCY2, ADCY1, ADCY6, ADCY8, CFTR, ATP1A2, ABCB1, ATP1A3, FXYD2, ADCY5, PRKACA, ATP1A1, PRKACB, ATP1B1	1481	62	5892	1.5400230881488097	0.9981359971685293	0.04024633000434552	27.091861960289243
KEGG_PATHWAY	hsa05110:Vibrio cholerae infection	19	1.0220548682087143	0.03837917944575391	KCNQ1, ADCY3, GNAS, ADCY9, PRKCA, PRKCG, ACTB, PRKACG, PLCG1, PRKCB, ATP6V0A1, PDIA4, CFTR, PLCG2, SLC12A2, ACTG1, PRKACA, PRKACB, TJP1	1481	48	5892	1.5747805536799462	0.9999618931497604	0.0639367079104407	40.04272316618308
KEGG_PATHWAY	hsa04330:Notch signaling pathway	19	1.0220548682087143	0.03837917944575391	NCOR2, EP300, HDAC2, PSEN1, SNW1, CREBBP, PSEN2, DVL3, ADAM17, HDAC1, NOTCH1, RBPJL, NOTCH2, CTBP1, MAML2, NOTCH4, DVL2, DVL1, NOTCH3	1481	48	5892	1.5747805536799462	0.9999618931497604	0.0639367079104407	40.04272316618308
KEGG_PATHWAY	hsa04672:Intestinal immune network for IgA production	18	0.9682625067240451	0.04052466015308475	CD40, MAP3K14, CXCR4, HLA-DRB1, IL6, TNFRSF17, IL5, IL2, HLA-DRA, HLA-DPB1, CXCL12, TNFSF13, ITGB7, IL10, IL15RA, HLA-DMB, CCR10, TGFB1	1481	45	5892	1.5913571910871032	0.9999786797424093	0.06703967131414235	41.76790574623127
KEGG_PATHWAY	hsa04973:Carbohydrate digestion and absorption	16	0.8606777837547067	0.04501518497182731	PIK3R5, PIK3CG, AKT3, PIK3R1, PIK3CD, ATP1A2, PIK3R3, PIK3CB, ATP1A3, AKT2, PIK3CA, FXYD2, PIK3R2, ATP1A1, AKT1, ATP1B1	1481	39	5892	1.6321612216277983	0.9999937037615335	0.07389383190392607	45.23135323857112
KEGG_PATHWAY	hsa04070:Phosphatidylinositol signaling system	30	1.6137708445400751	0.05195479309314899	ITPR3, PRKCA, PLCB1, PIK3CG, PLCB3, INPPL1, ITPR1, PLCB4, CALML5, CALML6, PIK3R1, CALM3, PIK3CD, CALML3, PIK3C2A, PIK3R3, PLCG2, PLCB2, PLCE1, PIK3R5, PRKCG, PLCG1, PRKCB, INPP5K, INPP5D, PIK3CB, PIK3C3, PIK3CA, PIK3R2, PTEN	1481	87	5892	1.371859647488882	0.9999990547380252	0.08456456141738422	50.21134548980734