TimeXNet Web - Identify active gene networks and pathways using time-course biological data

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TimeXNet Web - Identify active gene networks and pathways using time-course biological data

Notice: TimeXNet Web will be temporarily affected due to Human Genome Center server maintenance until February 21 (Wednesday) 09:00 JST.

Examples

Study

Species

Cell Type

Stimulus

Input Data Type

Input Network

Reference

Phosphoproteome of mouse WT BMDCs stimulated with LPS

Mus musculus

WT mouse bone marrow derived cells

LPS stimulated BMDCs profiled for phosphorylation levels at 0.25-6h

Phosphorylation

KEGG pathways, Transfac, HitPredict

Mertins et al., Cell Reports, 2017

Proteome profiling of HeLa cells with DTT-induced ER stress

Homo sapiens

HeLa cells

ER stress induced by dithiothreitol (DTT)

Protein Levels

KEGG pathways, Transfac, HitPredict

Cheng et al., Mol. Sys. Biol., 2017

Response of myeloma cells to chemotherapy

Homo sapiens

Human myeloma cells

Myeloma cells exposed to bortezomib profiled at 1.5-12 hours

Gene Expression

KEGG pathways, Transfac, HitPredict

Wiita et al., 2013

LPS response in mouse WT BMDCs

Mus musculus

Wild type bone marrow dendritic cells

LPS stimulated BMDCs profiled at 0.5-8 hours

Gene Expression

KEGG pathways, Transfac, HitPredict

Patil et al., 2013

LPS response in mouse MyD88 KO BMDCs

Mus musculus

MyD88 knock out bone marrow dendritic cells

LPS stimulated BMDCs profiled at 0.5-8 hours

Gene Expression

KEGG pathways, Transfac, HitPredict

Patil et al., 2013

LPS response in mouse TRIF KO BMDCs

Mus musculus

TRIF knock out bone marrow dendritic cells

LPS stimulated BMDCs profiled at 0.5-8 hours

Gene Expression

KEGG pathways, Transfac, HitPredict

Patil et al., 2013

Osmotic stress response in yeast

Saccharomyces cerevisiae

Wild type S. cerevisiae cells

Yeast cells under osmotic stress profiled at 2-15 minutes

Gene Expression

Network from Gitter et al., 2013

Romero-Santacreu et al., 2009